Results 81 to 90 of about 273,980 (263)

Prognostic Significance of Triglyceride Glucose Index in Intracerebral Hemorrhage

open access: yesMedical Sciences
Background: The triglyceride glucose index (TyG-i), a biomarker of insulin resistance, has been associated with adverse vascular outcomes and risk stratification in several cardiovascular and cerebrovascular phenotypes. However, data on TyG-i as a prognostic marker in spontaneous intracerebral hemorrhage (ICH) remain limited.
Giovanni Baronchelli   +15 more
openaire   +3 more sources

ALDH2 Deficiency Promotes Mitochondrial Oxidative Stress and Adverse Limb Outcomes via VDAC–HSP60 Signaling

open access: yesAdvanced Science, EarlyView.
ALDH2 deficiency promotes 4‐HNE accumulation, resulting in covalent modification of HSP60, disruption of its oligomeric assembly, and VDAC1‐dependent release of HSP60 from mitochondria to the cytosol. Pharmacological activation of ALDH2 preserves HSP60 proteostasis and mitochondrial integrity, whereas the clinical association between the ALDH2 rs671 ...
You‐Cheng Lin   +7 more
wiley   +1 more source

Sex-specific associations of the triglyceride-glucose index with systemic inflammation and arterial stiffness in adults with normal glucose and triglyceride levels

open access: yesAtherosclerosis Plus
The triglyceride-glucose (TyG) index is a surrogate marker of insulin resistance. However, its clinical relevance in individuals with strictly normal fasting glucose and triglyceride levels remains unclear. We aimed to investigate the sex-specific associations of the TyG index with systemic inflammation and arterial stiffness among adults with normal ...
Wei-Chen Shen   +7 more
openaire   +2 more sources

Hepatic morphology and serum biochemical profile according to dry and rainy seasons in Pygocentrus nattereri (Characiformes: Serrasalmidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract This study investigated the physiological and morphological adaptations of the liver of the carnivorous fish Pygocentrus nattereri (piranha) in response to seasonal variations (dry and rainy seasons) in the Brazilian Pantanal. The objective was to describe how the liver, a central organ in metabolic regulation, responds to environmental ...
Maria Eduarda Corona Garcia   +9 more
wiley   +1 more source

Comparative Meta‐Analysis of Antimicrobial Peptides in Aquatic and Terrestrial Livestock Species

open access: yesAnimal Research and One Health, EarlyView.
A global meta‐analysis of 58 studies (926 effect sizes and 29 species across five taxa) revealed that dietary antimicrobial peptides generally improve growth performance, blood metabolites, and immune responses. The greatest benefits were observed in omnivorous livestock, such as pigs and chickens. Dose‐duration effects were evident. An optimal outcome
Lily Liu   +4 more
wiley   +1 more source

The Impact of Triglyceride-Glucose Index Trajectories on Incidence and Recurrent Cardiovascular Events: Evidence from a Retrospective Cohort Study

open access: yesVascular Health and Risk Management
Yuan Xu,1,* Gonglong Wu,2,* Long Jiang,3 Xinlei Yang,1 Chengjin Wen,4 Yulan Yang,5 Hui Hu6 1Medical Big Data Center, The Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China; 2School of Public Health ...
Xu Y   +6 more
doaj  

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

open access: yesAnimal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu   +6 more
wiley   +1 more source

The triglyceride glucose index and cardiovascular disease outcomes

open access: yesThe Lancet Healthy Longevity, 2023
David, Flood   +2 more
openaire   +2 more sources

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

open access: yesAnimal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar   +8 more
wiley   +1 more source

Associations between metabolic-inflammatory biomarkers and Helicobacter pylori infection: an interpretable machine learning prediction approach

open access: yesFrontiers in Nutrition
BackgroundThis study investigated the association between metabolic-inflammatory markers and Helicobacter pylori (HP) infection using interpretable machine learning models, with a focus on the triglyceride-glucose (TyG) index, TyG/HDL-C ratio, and ...
Yue Zhang   +3 more
doaj   +1 more source

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