Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF) [PDF]
, 2018 Aims: Association of elevated circulating levels of trimethylamine N-oxide (TMAO) with adverse outcomes in patients with heart failure (HF) has been described.
Anker, Stefan D. +17 more
core +4 more sources
Clinical Interventions in Aging, 2021 Rui Huang,1,* Li Yan,2,* Yuhua Lei1 1Cardiovascular Disease Center, Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, Enshi Prefecture, 445000, Hubei Province, People’s Republic of China ...
Huang R, Yan L, Lei Y
doaj
Dye modification of nanofibrous silicon oxide membranes for colorimetric HCl and NH3 sensing [PDF]
, 2016 Colorimetric sensors for monitoring and visual reporting of acidic environments both in water and air are highly valuable in various fields, such as safety and technical textiles.
Breyne, Bet +8 more
core +1 more source
Trimethylamine N-Oxide: The Good, the Bad and the Unknown
Toxins, 2016 Trimethylamine N-oxide (TMAO) is a small colorless amine oxide generated from choline, betaine, and carnitine by gut microbial metabolism. It accumulates in the tissue of marine animals in high concentrations and protects against the protein ...
Manuel T. Velasquez +3 more
doaj +1 more source
Restored mutant receptor:Corticoid binding in chaperone complexes by trimethylamine N-oxide. [PDF]
PLoS ONE, 2017 Without a glucocorticoid (GC) ligand, the transcription factor glucocorticoid receptor (GR) is largely cytoplasmic, with its GC-binding domain held in high affinity conformation by a cluster of chaperones.
Aaron L Miller +5 more
doaj +1 more source
Trimethylamine N-Oxide and Cardiovascular Events in Hemodialysis Patients [PDF]
Journal of the American Society of Nephrology, 2016 Cardiovascular disease causes over 50% of the deaths in dialysis patients, and the risk of death is higher in white than in black patients. The underlying mechanisms for these findings are unknown. We determined the association of the proatherogenic metabolite trimethylamine N-oxide (TMAO) with cardiovascular outcomes in hemodialysis patients and ...
Tariq, Shafi +8 more
openaire +2 more sources
Role of gut microbiota-generated short chain fatty acids in metabolic and cardiovascular health [PDF]
, 2018 Purpose of this Review: This review assesses the latest evidence linking short-chain fatty acids (SCFA) with host metabolic health and cardiovascular disease (CVD) risk and presents the latest evidence on possible biological mechanisms.
Chambers, Edward S. +3 more
core +1 more source
Adaptations of Escherichia coli strains to oxidative stress are reflected in properties of their structural proteomes. [PDF]
, 2020 BACKGROUND:The reconstruction of metabolic networks and the three-dimensional coverage of protein structures have reached the genome-scale in the widely studied Escherichia coli K-12 MG1655 strain.
Catoiu, Edward +6 more
core +2 more sources
O2-independent demethylation of trimethylamine N-oxide by Tdm of Methylocella silvestris [PDF]
, 2016 Bacterial trimethylamine N-oxide (TMAO) demethylase, Tdm, carries out an unusual oxygen-independent demethylation reaction, resulting in the formation of dimethylamine and formaldehyde.
Blindauer, Claudia A. +5 more
core +1 more source
Trimethylamine N‐Oxide and Mortality Risk in Patients With Peripheral Artery Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundProduction of the proatherogenic metabolite, trimethylamine N‐oxide (TMAO), from dietary nutrients by intestinal microbiota enhances atherosclerosis development in animal models and is associated with atherosclerotic coronary artery disease in ...
Vichai Senthong +5 more
doaj +1 more source