Results 101 to 110 of about 453,912 (274)

Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
In the article by Chen et al, “Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway,” which published online September 4, 2017, and appeared in the September 2017 issue ...
L. Wilkins
semanticscholar   +1 more source

Pathogenic mutations in the hydrophobic core of the human prion protein can promote structural instability and misfolding [PDF]

, 2010
Transmissible spongiform encephalopathies, or prion diseases, are caused by misfolding and aggregation of the prion protein PrP. These diseases can be hereditary in humans and four of the many disease-associated missense mutants of PrP are in the ...
Daggett, Valerie, van der Kamp, Marc W
core   +2 more sources

Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-κB (Nuclear Factor κB) Signals

Arteriosclerosis, Thrombosis and Vascular Biology, 2020
Supplemental Digital Content is available in the text. Objectives: Vascular calcification is highly prevalent in patients with chronic kidney disease. Increased plasma trimethylamine N-oxide (TMAO), a gut microbiota-dependent product, concentrations are ...
Xiuli Zhang, Yining Li, Pingzhen Yang, Xiaoyu Liu, Lihe Lu, Yanting Chen, Xinglong Zhong, Zehua Li, Hailin Liu, Caiwen Ou, Jianyun Yan, Minsheng Chen   +11 more
semanticscholar   +1 more source

Pengaruh Penyiangan Dan Suhu Penyimpanan Terhadap Mutu Kimiawi, Mikrobiologis Dan Organoleptik Ikan Tongkol (Auxis Tharzard, Lac) [PDF]

, 2007
Ikan tongkol merupakan salah satu bahan pangan yang dikonsumsi masyarakat dan jika dibiarkanpada suhu kamar, maka terjadi proses penurunan mutu menjadi busuk.
Adiputra, N. (N), Arka, I. B. (I), Suranaya Pandit, I G, Suryadhi, N. T. (N)   +3 more
core  

Atherothrombosis and Oxidative Stress: Mechanisms and Management in Elderly [PDF]

, 2017
Significance: The incidence of cardiovascular events (CVEs) increases with age, representing the main cause of death in an elderly population. Aging is associated with overproduction of reactive oxygen species (ROS), which may affect clotting and ...
Carnevale, Roberto, Loffredo, Lorenzo, Pastori, Daniele, Pignatelli, Pasquale, Violi, Francesco   +4 more
core   +1 more source

The food-derived metabolite trimethylamine and trimethylamine-N-oxide promote colorectal cancer progression via SREBF1

Ecotoxicology and Environmental Safety
Colorectal cancer (CRC) is characterised by microbial dysbiosis. Trimethylamine (TMA) and trimethylamine-N-oxide (TMAO) are gut microbiota-derived metabolites produced from dietary precursors that are implicated in CRC progression.
Yang Yan, Jiaxuan Li, Hejia Xu, Chen Yang, Guifang Li, Yanyan Feng, Qian Wang, Li Li, Rendi Wu, Hairong Sun, Ting Zhang, Fang Wang, Yong Mao   +12 more
doaj   +1 more source

The N‐oxidation of trimethylamine in a Jordanian population. [PDF]

British Journal of Clinical Pharmacology, 1995
The ability to oxidise trimethylamine (TMA) to trimethylamine N‐oxide (TMAO) is distributed polymorphically within a British white population with the majority of individuals excreting greater than 90% of total urinary TMA as TMAO. The opposite extreme is characterised by a rare inborn error of TMA N‐oxidation known as the fish‐odour syndrome.
H F, Hadidi, S, Cholerton, S, Atkinson, Y M, Irshaid, N M, Rawashdeh, J R, Idle   +5 more
openaire   +2 more sources

Gut Microbial Signatures of Distinct Trimethylamine N-Oxide Response to Raspberry Consumption [PDF]

, 2022
Maximilien Franck, Juan de Toro‐Martín, Thibault Varin, Véronique Garneau, Geneviève Pilon, Denis Roy, Patrick Couture, Charles Couillard, André Marette, Marie‐Claude Vohl   +9 more
openalex   +1 more source

Trimethylamine-N-Oxide

JACC: Basic to Translational Science, 2021
Fadi W. Adel, Horng H. Chen
openaire   +1 more source

Comparative genomics and mutagenesis analyses of choline metabolism in the marine Roseobacter clade [PDF]

, 2015
Choline is ubiquitous in marine eukaryotes and appears to be widely distributed in surface marine waters; however, its metabolism by marine bacteria is poorly understood.
Andresen P.A., Gauthier M.J., Ghoul M., Ikawa M., Kiene R.P., Nau‐Wagner G., Prado S.   +6 more
core   +1 more source