Results 111 to 120 of about 453,912 (274)
Trimethylamine N-oxide: a meta-organismal axis linking the gut and fibrosis
Molecular MedicineTissue fibrosis is a common pathway to failure in many organ systems and is the cellular and molecular driver of myriad chronic diseases that are incompletely understood and lack effective treatment.
Jae Woong Jang +5 more
semanticscholar +1 more source
Trimethylamine N-Oxide Exacerbates Cardiac Fibrosis via Activating the NLRP3 Inflammasome
Frontiers in Physiology, 2019 Background/Aims: Gut microbiota has been reported to correlate with a higher mortality and worse prognosis of cardiovascular diseases. Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite of specific dietary nutrients, which is linked ...
Xueling Li +7 more
doaj +1 more source
American Journal of Clinical Nutrition, 2020 BACKGROUND Trimethylamine N-oxide (TMAO), a compound derived from diet and metabolism by the gut microbiome, has been associated with several chronic diseases, although the mechanisms of action are not well understood and few human studies have ...
B. Fu +11 more
semanticscholar +1 more source
Gut microbiota in atherosclerosis: focus on trimethylamine N‐oxide
Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 2020 The increasing prevalence of cardiovascular diseases cannot adequately be explained by traditional risk factors. Recently, accumulating evidence has suggested that gut microbiota‐derived numerous metabolites are contributors to atherosclerotic events ...
Yingqian Zhu, Qingqing Li, Hua Jiang
semanticscholar +1 more source
Gut Microbe-Generated Metabolite Trimethylamine-N-Oxide and Ischemic Stroke
BiomoleculesTrimethylamine-N-oxide (TMAO) is a gut microbiota-derived metabolite, the production of which in vivo is mainly regulated by dietary choices, gut microbiota, and the hepatic enzyme flavin monooxygenase (FMO), while its elimination occurs via the kidneys.
Zhen Li, Xinyi He, Qi Fang, Xulong Yin
doaj +1 more source
Temperature dependence of the hydrogen bond network in Trimethylamine N-oxide and guanidine hydrochloride - water solutions [PDF]
, 2017 We present an X-ray Compton scattering study on aqueous Trimethylamine N-oxide (TMAO) and guanidine hydrochloride solutions (GdnHCl) as a function of temperature. Independent from the concentration of the solvent, Compton profiles almost resemble results
Elbers, Mirko +10 more
core +2 more sources
Effect of urea and tmao on lipid bilayers
European Pharmaceutical Journal, 2017 We study the effect of the osmolytes, Urea and trimethylamine-N-oxide (TMAO) on POPE (1-palmitoyl-2-oleoyl-sn-glycero-3- phosphoethanolamine) lipid membranes using SAXS/WAXS and DSC.
Valerio J., Bernstorff S., Funari S.S.
doaj +1 more source
Flavoprotein monooxygenases for oxidative biocatalysis: recombinant expression in microbial hosts and applications [PDF]
, 2014 External flavoprotein monooxygenases comprise a group of flavin-dependent oxidoreductases that catalyze the insertion of one atom of molecular oxygen into an organic substrate and the second atom is reduced to water. These enzymes are involved in a great
Bianchi, Dario Alejandro +2 more
core +2 more sources
Association between risk of preeclampsia and maternal plasma trimethylamine-N-oxide in second trimester and at the time of delivery [PDF]
, 2020 Xin Huang +7 more
openalex +1 more source