Results 51 to 60 of about 453,912 (274)

Quantification of Trimethylamine-N-Oxide and Trimethylamine in Fish Oils for Human Consumption

Molecules
Supplementing fish oil is one of the strategies to reduce the risk of cardiovascular disease, the leading cause of death around the world. Contradictorily, fish oil may also contain trimethylamine-N-oxide, a recently emerged risk factor for ...
Dominik Dörfel, Sascha Rohn, Eckard Jantzen   +2 more
doaj   +1 more source

Analysis of metabolomic patterns in thoroughbreds before and after exercise [PDF]

Asian-Australasian Journal of Animal Sciences, 2017
Objective Evaluation of exercise effects in racehorses is important in horseracing industry and animal health care. In this study, we compared metabolic patterns between before and after exercise to screen metabolic biomarkers for exercise effects in ...
Hyun-Jun Jang, Duk-Moon Kim, Kyu-Bong Kim, Jeong-Woong Park, Jae-Young Choi, Jin Hyeog Oh, Ki-Duk Song, Suhkmann Kim, Byung-Wook Cho   +8 more
doaj   +1 more source

The Role of Gut Microbiota-Derived Trimethylamine N-Oxide in the Pathogenesis and Treatment of Mild Cognitive Impairment

International Journal of Molecular Sciences
Mild cognitive impairment (MCI) represents a transitional stage between normal aging and dementia, often considered critical for dementia prevention. Despite its significance, no effective clinical treatment for MCI has yet been established.
Haihua Xie, Jia Jiang, Sihui Cao, Xuan Xu, Jingying Zhou, Ruhan Zhang, Bo Huang, Penghui Lu, Liang Peng, Mi Liu   +9 more
semanticscholar   +1 more source

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota [PDF]

, 2014
Dietary intake of L-carnitine can promote cardiovascular diseases in humans through microbial production of trimethylamine (TMA) and its subsequent oxidation to trimethylamine N-oxide (TMAO) by hepatic flavin-containing monooxygenases.
Bugg, Tim, Chen, Yin, Cosatti, Marialuisa, Jameson, Eleanor, Rajakumar, Kumar, Schäfer, Hendrik, Zhu, Yijun   +6 more
core   +1 more source

Transient trimethylaminuria related to menstruation

BMC Medical Genetics, 2007
Background Trimethylaminuria, or fish odor syndrome, includes a transient or mild malodor caused by an excessive amount of malodorous trimethylamine as a result of body secretions.
Yamazaki Hiroshi, Cashman John R, Shimizu Makiko   +2 more
doaj   +1 more source

On the Road to Accurate Biomarkers for Cardiometabolic Diseases by Integrating Precision and Gender Medicine Approaches [PDF]

, 2019
The need to facilitate the complex management of cardiometabolic diseases (CMD) has led to the detection of many biomarkers, however, there are no clear explanations of their role in the prevention, diagnosis or prognosis of these diseases.
Argano, Vincenzo, Balistreri, Carmela Rita, Giarratana, Rosa Maria, Lio, Domenico, Scola, Letizia, Torre, Salvatore   +5 more
core   +1 more source

Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women

European Heart Journal, 2018
AIMS Carnitine and choline are major nutrient precursors for gut microbiota-dependent generation of the atherogenic metabolite, trimethylamine N-oxide (TMAO).
Zeneng Wang, N. Bergeron, B. Levison, Xinmin S Li, S. Chiu, Xun Jia, Robert A. Koeth, Lin Li, Yuping Wu, W. Tang, R. Krauss, S. Hazen   +11 more
semanticscholar   +1 more source

Structural mechanism for bacterial oxidation of oceanic trimethylamine into trimethylamine N -oxide [PDF]

, 2017
Trimethylamine (TMA) and trimethylamine N-oxide (TMAO) are widespread in the ocean and are important nitrogen source for bacteria. TMA monooxygenase (Tmm), a bacterial flavin-containing monooxygenase (FMO), is found widespread in marine bacteria and is ...
Chen, Xiu-Lan, Chen, Yin, Li, Chun-Yang, Li, Ping-Yi, Peng, Ming, Qin, Qi-Long, Sheng, Qi, Shi, Mei, Song, Xiao-Yan, Su, Hai-Nan, Wang, Peng, Xie, Bin-Bin, Xun, Lu-Ying, Zhang, Dian, Zhang, Xi-Ying, Zhang, Yu-Zhong, Zhou, Bai-Cheng   +16 more
core   +1 more source

The Influence of Prebiotic Arabinoxylan Oligosaccharides on Microbiota Derived Uremic Retention Solutes in Patients with Chronic Kidney Disease: A Randomized Controlled Trial. [PDF]

PLoS ONE, 2016
UNLABELLED:The colonic microbial metabolism is a key contributor to uremic retention solutes accumulating in patients with CKD, relating to adverse outcomes and insulin resistance.
Ruben Poesen, Pieter Evenepoel, Henriette de Loor, Jan A Delcour, Christophe M Courtin, Dirk Kuypers, Patrick Augustijns, Kristin Verbeke, Björn Meijers   +8 more
doaj   +1 more source

Gut microbiota-derived trimethylamine N-Oxide: a novel target for the treatment of preeclampsia

Gut microbes
Pre-eclampsia (PE) is the most common complication of pregnancy and seriously threatens the health and safety of the mother and child. Studies have shown that an imbalance in gut microbiota can affect the progression of PE.
Jiayi Wang, Yajie Gao, Shuaijun Ren, Jialin Li, Siqian Chen, Jiating Feng, Bing He, Yuping Zhou, Rongrong Xuan   +8 more
semanticscholar   +1 more source