Results 61 to 70 of about 453,912 (274)
Biomolecules & biomedicine, 2023 Current research supports the evidence that the gut microbiome (GM), which consists of gut microbiota and their biologically active metabolites, is associated with atherosclerosis development.
Y. Oktaviono +6 more
semanticscholar +1 more source
Prebiotic, Probiotic, and Synbiotic Supplementation in Chronic Kidney Disease: A Systematic Review and Meta-analysis [PDF]
, 2019 Gut dysbiosis has been implicated in the pathogenesis of chronic kidney disease (CKD). Restoring gut microbiota with prebiotic, probiotic, and synbiotic supplementation has emerged as a potential therapeutic intervention but has not been systematically ...
Campbell, Katrina L. +3 more
core +1 more source
The dietary source of trimethylamine N-oxide and clinical outcomes: an unexpected liaison
Clinical Kidney Journal, 2023 The profile of gut microbiota can vary according to host genetic and dietary characteristics, and be influenced by disease state and environmental stressors. The uremic dysbiosis results in a loss of biodiversity and overgrowth of microorganisms that may
M. Evans +4 more
semanticscholar +1 more source
Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction
Cellular Physiology and Biochemistry, 2017 Background/Aim: Plasma trimethylamine-N-oxide (TMAO), a product of intestinal microbial metabolism of dietary phosphatidylcholine has been recently associated with atherosclerosis and increased risk of cardiovascular diseases (CVD) in rodents and humans.
Krishna M. Boini +3 more
doaj +1 more source
Nutrients, 2023 Trimethylamine N-oxide (TMAO) is a microbial metabolite derived from nutrients, such as choline, L-carnitine, ergothioneine and betaine. Recently, it has come under the spotlight for its close interactions with gut microbiota and implications for ...
Edoardo Tacconi +6 more
semanticscholar +1 more source
Gut Metabolite Trimethylamine-N-Oxide in Atherosclerosis: From Mechanism to Therapy
Frontiers in Cardiovascular Medicine, 2021 Atherosclerosis is associated with various pathological manifestations, such as ischemic heart disease, ischemic stroke, and peripheral arterial disease, and remains a leading cause of public health concern.
BingYu Wang +6 more
doaj +1 more source
A New Light on Vitamin D in Obesity: A Novel Association with Trimethylamine-N-Oxide (TMAO) [PDF]
, 2019 : Vitamin D deficiency and obesity are two public health problems extensively exacerbated over the last years. Among the several mechanisms proposed to account for the complex interplay between vitamin D and obesity, one that has gained particular ...
Annunziata, G. +7 more
core +1 more source
Reduction of trimethylamine N-oxide to trimethylamine by the human gut microbiota: supporting evidence for ‘metabolic retroversion’ [PDF]
, 2015 Dietary sources of methylamines such as choline, trimethylamine (TMA), trimethylamine N-oxide (TMAO), phosphatidylcholine (PC) and carnitine are present in a number of foodstuffs, including meat, fish, nuts and eggs.
Chilloux, J +4 more
core +3 more sources
Gut‒heart axis: emerging therapies targeting trimethylamine N-oxide production
Gut MicrobesTrimethylamine N-oxide (TMAO) has garnered considerable attention because of its role in the pathophysiology and pathogenesis of various disorders, particularly heart and kidney disease.
Efrain Ricardo Torres +2 more
doaj +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2023 Shenghong Qi,1,2 Lan Liu,1,2 Shulan He,1,2 Liqun Wang,1,2 Jiangping Li,1,2 Xian Sun1,2 1School of Public Health and Management, Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 2The Key Laboratory of Environmental Factors and ...
Qi S, Liu L, He S, Wang L, Li J, Sun X
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