Results 151 to 159 of about 10,078 (159)

The Uremic Metabolite, Trimethylamine‐N‐Oxide (TMAO), Directly Alters Cardiac Contractile Function

The FASEB Journal, 2017
Background TMAO is produced by intestinal microbial metabolism of phosphatidylcholine. Clearance of this uremic metabolite is dependent on urinary excretion. Therefore, as kidney function declines during chronic kidney disease (CKD), plasma levels of TMAO increase.
Carlee Oakley, Matt Hendrix, Michael Grillo, Darla McCarthy, Jason R. Stubbs, Michael J. Wacker   +5 more
openaire   +1 more source

Bariatric surgery could impact trimethylamine-n-oxide (TMAO) Metabolism

Clinical Nutrition ESPEN, 2023
J.T.M. Alves, A.P.D.A. Prudêncio, D.C. Fonseca, N.M. Machado, R.S.D.M.M. Torrinhas, D.L. Waitzberg   +5 more
openaire   +1 more source

Trimethylamine N-oxide (TMAO) effects on isolated adult rat cardiomyocytes

Vascular Pharmacology, 2020
G. Querio, S. Antoniotti, R. Levi, M.P. Gallo   +3 more
openaire   +1 more source

Abstract 2222: Trimethylamine-N-oxide (TMAO) mediates immunotherapy resistance in advanced HCC

Cancer Research
Abstract Recent approvals of immune checkpoint inhibitor (ICI) based regimens have transformed the clinical landscape of advanced hepatocellular carcinoma (HCC), however, clinical responses are only observed in a minority of patients. Trimethylamine-N-oxide (TMAO) is an amine oxide biosynthesized from trimethylamine (TMA), generated when
Mari Nakazawa, Vivian L. Raj, NV Rajeshkumar, Noushin Rastkari, Michael Davis, Elizabeth De Oliveria, Madelena Brancati, Ervin Griffin, Kabeer Munjal, James Leatherman, Sarah Mitchell, Marina Baretti, Won Jin Ho, Mark Yarchoan, Chi V. Dang   +14 more
openaire   +1 more source

Characterization of trimethylamine-N-oxide (TMAO) demethylase activity from fish muscle microsomes.

Journal of biochemistry, 1986
A crude microsomal fraction isolated from red hake (Urophycis chuss) muscle demethylated trimethylamine-N-oxide (TMAO). Two cofactor systems were capable of stimulating activity; the system of NADH and FMN required anaerobic conditions while the other system, composed of iron and cysteine and/or ascorbate functioned in the presence or absence of oxygen.
K L, Parkin, H O, Hultin
openaire   +1 more source

Trimethylamine N-oxide (TMAO)

Cold Spring Harbor Protocols, 2006
openaire   +1 more source

Raman Spectroscopic Signatures of Noncovalent Interactions Involving Trimethylamine N-oxide (TMAO)

AIP Conference Proceedings, 2010
Katherine L. Munroe, David H. Magers, Nathan I. Hammer, P. M. Champion, L. D. Ziegler   +4 more
openaire   +1 more source

Characterization of Trimethylamine-N-Oxide (TMAO) Demethylase Activity from Fish Muscle Microsomes1

The Journal of Biochemistry, 1986
Kirk L. PARKIN, Herbert O. HULTIN
openaire   +1 more source

Trimethylamine (Tma) And Trimethylamine-N-Oxide (Tmao) As Predictors Of Cardiovascular Mortality In Peripheral Artery Disease

Atherosclerosis, 2019
C. Roncal, E. Martínez-Aguilar, J. Orbe, S. Ravassa, A. Fernandez-Montero, G. Saenz De Pipaon, A. Ugarte, A. Estella-Hermoso de Mendoza, J.A. Rodriguez, S. Fernández-Alonso, L. Fernández-Alonso, J. Oyarzabal, J.A. Paramo   +12 more
openaire   +1 more source