Results 81 to 90 of about 10,078 (159)

Relationship Between Dietary Choline Intake and Cognitive Function in the United States: A Cross‐Sectional Study of the 2011–2014 NHANES Cycle

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
In this study, we found a negative relationship between choline intake (dietary choline and total choline) and cognitive function in the elderly population of the United States. RCS analysis showed a U‐shaped association between choline intake and cognitive test (DSST) scores. Interaction analysis suggests that gender and hypertension status may affect
Yu‐hang Chen, Ting‐ting Liu, Li‐ming Chen   +2 more
wiley   +1 more source

Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation

iMetaOmics, Volume 3, Issue 1, March 2026.
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu, Zhibiao Li, Lin Yang, Jun Zheng, Weijia Li, Rulin Liao, Wenxue Huang, Boyuan Sun, Zhuohang Li, Cunzhen Ma, Xunguo Yang, Zongwei Wang, Jie Zhao, Bisheng Cheng, Peng Wu   +14 more
wiley   +1 more source

Advance Microbiota Transplantation: A Novel Addition–Subtraction Paradigm for Optimising Faecal Microbiota Transplantation

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
This review proposes Advance Microbiota Transplantation (AMT), a pre‐peri‐post transplant ‘addition–subtraction’ framework that integrates donor–recipient optimisation, product engineering, and post‐transplant recipient adjuvant management to enhance conventional FMT efficacy and mitigate its limitations. ABSTRACT Faecal microbiota transplantation (FMT)
Haojia Lin, Zelin Feng, Qiuyue Tu, Huizhen Li, Yanru Zhang, Xinyue Wei, Qinghua Yi, Hetong Zhang, Yu Wang, Xiaoqin Li, Yueting Li, Jun Huang, Zehan Chen, Hongtian Shentu, Anjiang Wang, Ye Chen, Xiaolong He, Xiaocang Cao   +17 more
wiley   +1 more source

A Multi‐Organ Atlas Links Gut Microbial Metabolites to Systemic Redox Changes in Aging Mice

Aging Cell, Volume 25, Issue 3, March 2026.
A gut‐derived metabolic signature drives systemic aging phenotypes. Integrated multi‐omics profiling of young versus aged mice identifies a conserved aging signature characterized by the depletion of protective lysophosphatidylcholines (LPC 22:0) and the concurrent accumulation of pro‐oxidative microbial catabolites (TMAO, IAA).
Sanaullah Sajid, Jieliang Huang, Shaofang Kong, Chengze Lai, Zhuoxin Tan, Yiming Shao, Lianxian Guo   +6 more
wiley   +1 more source

Impacts of Lifestyle and Microbiota‐Targeted Interventions for Overweight and Obesity on the Human Gut Microbiome: A Systematic Review

Obesity Reviews, Volume 27, Issue 3, March 2026.
Dietary interventions showed the strongest evidence for improving microbiome composition. Probiotics and prebiotics consistently increased beneficial bacteria. Exercise and fecal microbiota transplantation had limited evidence but showed potential for microbiome modulation.
Yee Teng Lee, Ayça Akan, Dilara Beyza Önel, Evelyn Medawar, Daria E. A. Jensen, Arno Villringer, A. Veronica Witte   +6 more
wiley   +1 more source

Trimethylamine N‐oxide is elevated in postmenopausal women relative to age‐matched men and premenopausal women among individuals with obesity

Experimental Physiology, Volume 111, Issue 3, Page 798-808, 1 March 2026.
Abstract Trimethylamine N‐oxide (TMAO) is linked to arterial stiffness and atherosclerosis. Cardiovascular disease (CVD) risk increases following menopause in women. Whether menopause influences plasma TMAO metabolism to mediate CVD risk is unknown.
Daniel J. Battillo, Steven K. Malin
wiley   +1 more source

A pilot study of maternal vitamin D status and its association with breast milk and infant gut metabolites

Physiological Reports, Volume 14, Issue 5, March 2026.
Vitamin D status in our pilot study was associated with higher levels of certain amino acids and hexanoic acid in breast milk and metabolites in infant stool samples. Abstract Human milk contains multiple bioactive components, many of which are influenced by the mother's nutritional status.
Alyssa S. Gutierrez, Katherine E. Chetta, Santosh Thapa, Sigmund J. Haidacher, Kathleen M. Hoch, John E. Baatz, Anthony M. Haag, Numan Oezguen, Thomas D. Horvath, Carol L. Wagner, Melinda A. Engevik   +10 more
wiley   +1 more source

The Gut Microbial-Derived Metabolite Trimethylamine N-Oxide and Atrial Fibrillation: Relationships, Mechanisms, and Therapeutic Strategies

Clinical Interventions in Aging, 2021
Rui Huang,1,* Li Yan,2,* Yuhua Lei1 1Cardiovascular Disease Center, Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, Enshi Prefecture, 445000, Hubei Province, People’s Republic of China ...
Huang R, Yan L, Lei Y
doaj  

Increased circulating trimethylamine N-oxide plays a contributory role in the development of endothelial dysfunction and hypertension in the RUPP rat model of preeclampsia

Hypertension in Pregnancy, 2019
Objective: We examined whether trimethylamine-N-oxide (TMAO) plays a role in endothelial dysfunction and hypertension in the reduced uterine perfusion pressure (RUPP) rat model of preeclampsia (PE).
Hui Chen, Jiabao Li, Ning Li, Hongsheng Liu, Jiyun Tang   +4 more
doaj   +1 more source

Research progress on the association between TMAO and vascular calcification in patients with chronic kidney disease

Renal Failure
Vascular calcification (VC) is a common complication in patients with chronic kidney disease (CKD) and a major risk factor for increased cardiovascular mortality in patients with CKD.
Yuxin Zhang, Liangying Huang, Santao Ou
doaj   +1 more source