Results 11 to 20 of about 12,469 (237)
Thermolabile Triose Phosphate Isomerase in a Psychrophilic Clostridium [PDF]
Journal of Bacteriology, 1972 The psychrophile Clostridium sp. strain 69 contains a thermolabile triose phosphate isomerase which is inactivated rapidly in vitro and in vivo at 32 C.
Yuen Shing +2 more
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Discovery and validation of small molecule stabilizers of mutant triose phosphate isomerase (TPI) as potential lead candidates for TPI deficiency [PDF]
SLAS DiscoveryTriosephosphate Isomerase deficiency (TPI-Df) is a devastating untreatable childhood metabolic disease resulting in anemia, severe locomotor impairment, and premature death.
Laura L. Vollmer +15 more
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New inhibitors of rabbit muscle triose-phosphate isomerase
Bioorganic & Medicinal Chemistry Letters, 2005 We describe the synthesis and evaluation of three new competitive inhibitors of triose-phosphate isomerase. One of them (phosphoglycoloamidoxime: K(i) = 4.5 microM) is among the best reversible inhibitors so far reported for this enzyme.
Matthieu Fonvielle +2 more
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Studies of triose phosphate isomerase by hydrogen exchange [PDF]
Biochemical Journal, 1974 The3H–H exchange of chicken muscle and rabbit muscle triose phosphate isomerases was studied. Their behaviour was mostly very similar. ‘Exchange-in’ (acquisition of radioactivity when protein was incubated in3H2O) was measured at 37°C and at pH7.5, and the rates of exchange of the native and liganded enzymes were compared.
Christopher Browne, Stephen G. Waley
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Protein chemistry of triose phosphate isomerase
, 2010 The protein, triose phosphate isomerase (TIM) has been isolated from fresh chicken breast muscle and purified by anion exchange chromatography on DSAE Sephadex A50 column. Further purification proceeded via Biogel A DEAE resin. The TIM fractions of both chromatographies were contained in two adjacent protein peaks, A and B.
Helen D. Burgess
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Characterization of Sinorhizobium meliloti triose phosphate isomerase genes. [PDF]
J Bacteriol, 2007 ABSTRACT A Tn 5 mutant strain of Sinorhizobium meliloti with an insertion in tpiA (systematic identifier SMc01023), a putative triose phosphate isomerase (TPI)-encoding gene, was isolated. The tpiA mutant grew more slowly than the wild
Poysti NJ, Oresnik IJ.
europepmc +4 more sources
Disequilibrium in the triose phosphate isomerase system in rat liver [PDF]
Biochemical Journal, 1969 1. The equilibrium constant at 38° and I 0·25 of the triose phosphate isomerase reaction was found to be 22·0 and that of the aldolase reaction, 0·99×10−4m. The [dihydroxyacetone phosphate]/[glyceraldehyde phosphate] ratio was found to be 9·3 in rat liver. The causes of the apparent deviation of the triose phosphate isomerase system from equilibrium in
Richard L. Veech +3 more
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Determination of Serum level of Triose Phosphate Isomerase in lung Cancer Patients
Armaghane Danesh Bimonthly Journal, 2015 Background & aim: Due to the fact that lung cancer is the most common cause of cancer-related deaths worldwide, identification of biomarkers is of great importance for early detection.
mohamadali Ghayyoumi, mahsa Mansouri
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Unusually long life in a child with Triose Phosphate Isomerase Deficiency
Pediatric Hematology Oncology Journal, 2022 Susan Salari +3 more
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