Results 31 to 40 of about 11,871 (215)
The heat released during catalytic turnover enhances the diffusion of an enzyme [PDF]
, 2014 Recent studies have shown that the diffusivity of enzymes increases in a substrate-dependent manner during catalysis,. Although this observation has been reported and characterized for several different systems–, the precise origin of this phenomenon is ...
Bustamante, Carlos +7 more
core +3 more sources
Identification and Characterization of Pituitary Triose‐Phosphate Isomerase [PDF]
European Journal of Biochemistry, 1972 Several pituitary preparations from various species, including two purified follicle‐stimulating hormone preparations, inhibited the D‐glyceraldehyde‐3‐phosphate dehydrogenase reaction. The active factor in those preparations that caused the apparent inhibition has been identified as an enzyme, triose phosphate isomerase.
M M, Greenberg, T T, Yen, J L, Bobbitt
openaire +2 more sources
Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis [PDF]
, 2013 Previous models of glycolysis in the sleeping sickness parasite Trypanosoma brucei assumed that the core part of glycolysis in this unicellular parasite is tightly compartimentalized within an organelle, the glycosome, which had previously been shown to ...
Achcar +30 more
core +1 more source
Metabolite concentrations, fluxes and free energies imply efficient enzyme usage. [PDF]
, 2016 In metabolism, available free energy is limited and must be divided across pathway steps to maintain a negative ΔG throughout. For each reaction, ΔG is log proportional both to a concentration ratio (reaction quotient to equilibrium constant) and to a ...
Amador-Noguez, Daniel +6 more
core +2 more sources
Frontiers in Microbiology, 2016 Our prior studies demonstrated that cellular response of T helper 1 (Th1) type was generated by a soluble antigenic fraction (ranging from 89.9–97.1 kDa) of Leishmania donovani promastigote, in treated Leishmania patients as well as hamsters and showed ...
SUMIT eJOSHI +13 more
doaj +1 more source
The critical role of methylglyoxal and glyoxalase 1 in diabetic nephropathy [PDF]
, 2013 The discovery of increased formation of methylglyoxal (MG) by cell metabolism in high glucose concentration in vitro suggested possible relevance to diabetes and diabetes complications (1,2).
Rabbani, Naila, Thornalley, Paul J.
core +1 more source
pH-dependence of the triose phosphate isomerase reaction [PDF]
Biochemical Journal, 1972 The pH-dependences of the kinetic parameters kcat. and Km for the triose phosphate isomerase reaction were determined in each direction. Apparent pKa values of 6.0 and 9.0 are observed in the dependences of kcat./Km. The pH-dependences of kcat. are sigmoid, with apparent pKa values of about 6.0.
B, Plaut, J R, Knowles
openaire +2 more sources
Applied Sciences, 2021 A proteomic method combining two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and matrix-assisted laser desorption/ionization-time-of-flight/time-of-flight mass spectrometry (MALDI-TOF/TOF) was used to compare the protein expression profiles ...
Hyun-Na Koo +4 more
doaj +1 more source
Diagnostic Alleles From Electrophoresis Distinguish Two Noctuid Pest Species, \u3ci\u3eHydraecia Immanis\u3c/i\u3e and \u3ci\u3eH. Micacea\u3c/i\u3e (Lepidoptera: Noctuidae). [PDF]
, 2017 Native hop vine borer (Hydraecia immanis) and introduced potato stem borer (H. micacea) populations in Midwest corn have reached noticeable levels near the Great Lakes plant community ecotone between boreal forests and temperate deciduous forests.
Bossart, Janice L +2 more
core +2 more sources
PLoS ONE, 2006 Triosephosphate isomerase (TPI) deficiency is an autosomal recessive disorder caused by various mutations in the gene encoding the key glycolytic enzyme TPI.
Markus Ralser +4 more
doaj +1 more source