Disequilibrium in the triose phosphate isomerase system in rat liver [PDF]
1. The equilibrium constant at 38° and I 0·25 of the triose phosphate isomerase reaction was found to be 22·0 and that of the aldolase reaction, 0·99×10−4m. The [dihydroxyacetone phosphate]/[glyceraldehyde phosphate] ratio was found to be 9·3 in rat liver. The causes of the apparent deviation of the triose phosphate isomerase system from equilibrium in
R L, Veech +3 more
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Folding and Association of Triose Phosphate Isomerase from Rabbit Muscle
The enzymatic activity and quaternary structure of rabbit muscle triose phosphate isomerase remains unchanged in the concentration range from 2 μg/ml to 2 ng/ml. In this concentration range the enzyme can be reactivated after dissociation and denaturation in 6.5 ᴍ guanidine hydrochloride. Removal of the denaturant by dilution and separation of inactive
S, Zabori, R, Rudolph, R, Jaenicke
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A High-Content Screening Assay for Small Molecules That Stabilize Mutant Triose Phosphate Isomerase (TPI) as Treatments for TPI Deficiency. [PDF]
Vogt A +6 more
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Characterization of stress and methylglyoxal inducible triose phosphate isomerase (OscTPI) from rice. [PDF]
Sharma S +4 more
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Triosephosphate isomerase from Fasciola hepatica: high-resolution crystal structure as a drug target. [PDF]
The high‐resolution crystal structure of triosephosphate isomerase from F. hepatica was solved at 1.51 Å resolution in its monoclinic form, revealing details of the dimer interface critical for enzyme function. Molecular docking with the fasciolocide triclabendazole suggests selective binding near nonconserved residues, highlighting this enzyme as a ...
Kontellas G +5 more
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Salt Stress Re-Routes Terpenoid and Flavonoid Metabolism in Peppermint (Mentha × Piperita L.). [PDF]
ABSTRACT Salt stress is a major abiotic factor limiting crop productivity. This study investigated the physiological and biochemical responses of peppermint (Mentha × piperita L.) to increasing NaCl concentrations (25, 50, and 100 mM). Terpenoids and flavonoids were analysed by GC–MS and HPLC‐ESI‐MS/MS, respectively, alongside Real‐Time PCR for key ...
Caldo F, Mannino G, Maffei ME.
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The active centre of triose phosphate isomerase [PDF]
The molecular weight and amino acid composition of triose phosphate isomerase have been determined. The molecular weight (43000) is lower and the molecular activity (500000) higher than those of most other glycolytic enzymes. Reaction with iodoacetate (studied with radioactive reagent) takes place in two phases: in the first phase, at pH6.3, cysteine ...
P M, Burton, S G, Waley
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The return of metabolism: biochemistry and physiology of glycolysis. [PDF]
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Grüning NM +19 more
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To determine the genotypes and zoonotic potentials of G. duodenalis isolates from different popula-tions of domestic dogs in Japan, a total of 114 Giardia positive samples were examined using multi-locus genotyping analysis at the 3 loci of glutamate ...
N. Itoh +3 more
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Prevalence and molecular characterization of Giardia intestinalis isolated from children and calves in Babylon province, Iraq [PDF]
Background and Aim: Giardia intestinalis is one of the most prevalent intestinal parasites in humans and animals, and children in close contact with livestock are particularly at risk of infection.
Haider H. Alseady +2 more
doaj +1 more source

