ADENOSINE TRIPHOSPHATASE LOCALIZATION IN AMPHIBIAN EPIDERMIS [PDF]
The localization of ATPase1 activity has been studied by light and electron microscopy in the epidermis of Rana pipiens, Rana catesbiana, and Bufo marinus. The reaction was carried out on skin (glutaraldehyde-fixed or fresh) sectioned with or without freezing. Best results were obtained with nonfrozen sections of fixed tissue.
George E. Palade, Marilyn G. Farquhar
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We propose a novel CHI3L1‐associated vascular phenotype classification for glioma, each characterized by unique tumor features, including immune cell infiltration, metabolic reprogramming, and genomic alterations. We identified CHI3L1‐associated vascular signatures that reflect tumor angiogenesis and immunosuppression.
Yu‐Hang Zhao+9 more
wiley +1 more source
Kinetics and regulation of the myofibrillar adenosine triphosphatase [PDF]
1. The steady-state kinetic behaviour of the ATPase (adenosine triphosphatase) of intact myofibrils was studied in the presence of both high and low concentrations of Ca2+ (0.25 mM and less than 10 nM respectively). 2. Kinetic data were collected over the initial linear phase of the assay, which lasts for 20–60s.
C M Wall, S V Perry, C C Goodno
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Assignment of the Human and Mouse Prion Protein Genes to Homologous Chromosomes [PDF]
Purified preparations of scrapie prions contain one major macromolecule, designated prion protein (PrP). Genes encoding PrP are found in normal animals and humans but not within the infectious particles.
Blatt, Cila+13 more
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Potential role of vacuolar H+–adenosine triphosphatase in neointimal formation in cultured human saphenous vein [PDF]
Objective: Vacuolar H+–adenosine triphosphatase plays a pivotal role in pH regulation and molecular transport across the vacuolar membranes and is involved in cell proliferation and transformation. In the present study, possible involvement of vacuolar H+
Fujii, Hirofumi+10 more
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Role of the RAB27/SYTL Axis in Tumor Microenvironment Construction
This review focuses on the role of the RAB27/SYTL axis in various cancer types associated with tumor microenvironment modifications. The importance of this pathway and the potential therapeutic strategies targeting vesicle production for the treatment of cancer are also discussed.
Miwa Tanaka, Takuro Nakamura
wiley +1 more source
The Iron-Type Nitrile Hydratase Activator Protein Is A GTPase [PDF]
The Fe-type nitrile hydratase activator protein from Rhodococcus equi TG328-2 (ReNHase TG328-2) was successfully expressed and purified. Sequence analysis and homology modeling suggest that it is a G3E P-loop guanosine triphosphatase (GTPase) within the ...
Bennett, Brian+3 more
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Toward molecular phenotyping of temporal lobe epilepsy by spatial omics
Abstract Objective In temporal lobe epilepsy (TLE), detection of the epileptogenic zone predicts a good surgical outcome. When submitted to 18F‐fluorodeoxyglucose positron emission tomography (PET), some patients display lateralized, focal hypometabolism in the temporal lobe (PET+), whereas others appear normometabolic (PET−).
Isabeau Vermeulen+33 more
wiley +1 more source
An investigation into the effects of Omega-3 fatty acids on bone resorption in the female ovariectomised rat : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Nutritional Science at Massey University [PDF]
Estrogen deficiency results in disruption of the normal bone remodeling cyclc leading to a loss of bone mineral and, in many cases, the development of osteoporosis.
Poulsen, Raewyn Carol
core
Severe thrombocytopenia in a patient with inosine triphosphatase (ITPA)–CC genotype caused by pegylated interferon (IFN)-α-2a with ribavirin therapy: a case report [PDF]
BACKGROUND: Pegylated interferon combined with ribavirin treatment is an effective therapy for chronic hepatitis C viral infection. However, pegylated interferon combined with ribavirin is associated with various adverse reactions.
Hiroyuki Kitagawa+4 more
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