Results 41 to 50 of about 38,432 (164)
Epigenetic control of cell identities from epiblast to gastrulation
In this review, we present and contextualize current knowledge about the roles of epigenetic modifiers during the development of mouse epiblast to gastrulation stage. The epigenetic regulation of enhancer and promoter elements by DNA methylation, histone modifications, and chromatin accessibility in concert with lineage‐specific transcription factors ...
Katrin M. Schüle, Simone Probst
wiley +1 more source
Conserved function of a RasGEF‐mediated pathway in the metabolic compensation of the circadian clock
Metabolic compensation of the circadian clock is essential for stabilizing the period of endogenous timekeeping in environments with significant nutrient fluctuations. In this study, we demonstrate that RasGEF (SOS1)‐mediated signaling, which is influenced by metabolic conditions, supports the robust function of the circadian clock under low glucose ...
Orsolya Sárkány+6 more
wiley +1 more source
Influence of Histamine on Adenosine Triphosphatase
In all snake venoms hitherto investigated a powerful ATP-ase (ophio-ATP-ase) has been found, which is activated by magnesium, calcium and cobalt ions and inhibited by zinc ions.1,2 Histamine and pyridoxamine act as inhibitors, epinephrine as activator.The question arose as to whether similar reactions take place in the animal tissues and thus ...
openaire +3 more sources
Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]
<p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J.+4 more
core +3 more sources
The certainty is moderate for a slightly higher platelet count in patients with periodontitis compared to individuals without periodontitis and low for no difference in mean platelet volume between the two groups. The evidence is not robust to claim a clear difference in other platelet activation biomarkers between the two groups.
Dimitris Sokos+6 more
wiley +1 more source
Mechanism of NaCl transport-stimulated prostaglandin formation in MDCK cells [PDF]
Recently we have found that stimulation of NaCl transport in high-resistance MDCK cells enhances their prostaglandin formation. In the present study, we investigated the mechanisms by which prostaglandin formation could be linked to the ion transport in ...
Bauer, C.+4 more
core +1 more source
Summary Food crops, as the cornerstone of human nutrition, not only provide essential macronutrients but also encompass a rich spectrum of bioactive compounds that promote health. Of particular significance are underutilized minor crops, which contain unique beneficial components with proven nutraceutical properties. These valuable bioactive components
Jie Wang, Zhaosheng Kong
wiley +1 more source
Inhibition of movement of trition-demembranated sea-urchin sperm flagella by Mg2+, ATP4-, ADP and P1 [PDF]
Three clinical patterns of inhibition of MgATP2--activated flagellar motility have been found by measuring the motility of Triton-demembranated sea-urchin spermatozoa beating with their heads attached to a glass surface.
Brokaw, C. J., Okuno, Makoto
core
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich+9 more
wiley +1 more source
Thiamine triphosphatase activity in bovine kidney [PDF]
AbstractProperties of soluble thiamine triphosphatase (ThTPase), adenosine triphosphatase, nucleoside triphosphatase and alkaline phosphatase activities in bovine kidney were compared. ThTPase and the other phosphatases differed clearly in their pH‐dependences, Km and molecular masses.
Alexander F Makarchikov+1 more
openaire +3 more sources