Type I Collagen Receptor (α2β1) Signaling Promotes Prostate Cancer Invasion through RhoC GTPase
Neoplasia: An International Journal for Oncology Research, 2008 The most frequent site of metastasis in human prostate cancer (PCa) is the bone. Preferential adhesion of PCa cells to bone-specific factors may facilitate the selective metastasis of the skeleton.
Christopher L. Hall +5 more
doaj +1 more source
Dynein structure and power stroke [PDF]
, 2003 Dynein ATPases are microtubule motors that are critical to diverse processes such as vesicle transport and the beating of sperm tails; however, their mechanism of force generation is unknown.
A Elliot +40 more
core +1 more source
Complete genome sequence and taxonomic position of anguillid herpesvirus 1 [PDF]
, 2010 Eel herpesvirus or anguillid herpesvirus 1 (AngHV1) frequently causes disease in freshwater eels. The complete genome sequence of AngHV1 and its taxonomic position within the family Alloherpesviridae were determined. Shotgun sequencing revealed a 249 kbp
Abma-Henkens, M.H.C. +8 more
core +3 more sources
Late-onset thymidine kinase 2 deficiency: a review of 18 cases [PDF]
, 2019 BACKGROUND: TK2 gene encodes for mitochondrial thymidine kinase, which phosphorylates the pyrimidine nucleosides thymidine and deoxycytidine. Recessive mutations in the TK2 gene are responsible for the 'myopathic form' of the mitochondrial depletion ...
Caballero Eraso, Candelaria +9 more
core +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2020 Background & Aims: Ral guanosine triphosphatase–activating protein α2 (RalGAPα2) is the major catalytic subunit of the negative regulators of the small guanosine triphosphatase Ral, a member of the Ras subfamily.
Tomoya Iida +12 more
doaj +1 more source
High inorganic triphosphatase activities in bacteria and mammalian cells: identification of the enzymes involved. [PDF]
PLoS ONE, 2012 BACKGROUND: We recently characterized a specific inorganic triphosphatase (PPPase) from Nitrosomonas europaea. This enzyme belongs to the CYTH superfamily of proteins.
Gregory Kohn +10 more
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Endogenous Mammalian Cardiotonic Steroids—A New Cardiovascular Risk Factor?—A Mini-Review
Life, 2021 The role of endogenous mammalian cardiotonic steroids (CTS) in the physiology and pathophysiology of the cardiovascular system and the kidneys has interested researchers for more than 20 years. Cardiotonic steroids extracted from toads or plants, such as
Natalia Słabiak-Błaż, Grzegorz Piecha
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An electron cytochemical demonstration and biochemical analysis of adenosine triphosphatase activity in cancer cell plasma membrane [PDF]
, 1968 1. The studies of structure and function of the plasma membranes of cancer cells is extremely important for the elucidation of specificity of phenotypes of cancer cells.
Koshiba, Kimikazu
core +1 more source
MgATP-induced inhibition of the adenosine triphosphatase activity of the chloroform-released mitochondrial adenosine triphosphatase [PDF]
Biochemical Journal, 1981 1. Preincubation of the ox heart chloroform-released mitochondrial ATPase with MgATP results in a time-dependent inhibition of ATPase activity. No re-activation occurs when MgATP remains in the preincubation medium. The enzyme activity returns when all the MgATP in the preincubation system has been hydrolysed. 2.
P N Lowe, R B Beechey
openaire +3 more sources
Plasmodium RNA triphosphatase validation as antimalarial target
International Journal for Parasitology: Drugs and Drug ResistanceTarget-based approaches have traditionally been used in the search for new anti-infective molecules. Target selection process, a critical step in Drug Discovery, identifies targets that are essential to establish or maintain the infection, tractable to ...
Sonia Moliner-Cubel +11 more
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