Results 41 to 50 of about 56,477 (262)

High inorganic triphosphatase activities in bacteria and mammalian cells: identification of the enzymes involved. [PDF]

PLoS ONE, 2012
BACKGROUND: We recently characterized a specific inorganic triphosphatase (PPPase) from Nitrosomonas europaea. This enzyme belongs to the CYTH superfamily of proteins.
Gregory Kohn, David Delvaux, Bernard Lakaye, Anne-Catherine Servais, Georges Scholer, Marianne Fillet, Benjamin Elias, Jean-Michel Derochette, Jacques Crommen, Pierre Wins, Lucien Bettendorff   +10 more
doaj   +1 more source

Endogenous Mammalian Cardiotonic Steroids—A New Cardiovascular Risk Factor?—A Mini-Review

Life, 2021
The role of endogenous mammalian cardiotonic steroids (CTS) in the physiology and pathophysiology of the cardiovascular system and the kidneys has interested researchers for more than 20 years. Cardiotonic steroids extracted from toads or plants, such as
Natalia Słabiak-Błaż, Grzegorz Piecha
doaj   +1 more source

Effect in vitro of the Phenobarbital on the Activity of the Enzyme Adenosine Triphosphatase (ATPase) of Sodium and Potassium Dependent in Human Placenta.

Medisur, 2007
Background: Most of the drugs can pass to the fetus through the placenta, conditioning alterations of the development and fetal growth. Objective: To evaluate the effect in vitro of Phenobarbital on the activity of adenosine triphosphatase of sodium and ...
María De Jesús Sánchez Bouza, Pedro Sánchez Frenes   +1 more
doaj   +2 more sources

An electron cytochemical demonstration and biochemical analysis of adenosine triphosphatase activity in cancer cell plasma membrane [PDF]

, 1968
1. The studies of structure and function of the plasma membranes of cancer cells is extremely important for the elucidation of specificity of phenotypes of cancer cells.
Koshiba, Kimikazu
core   +1 more source

Synonymous mutation in adenosine triphosphatase copper‐transporting beta causes enhanced exon skipping in Wilson disease

Hepatology Communications, 2022
Wilson disease (WD) is caused by biallelic pathogenic variants in adenosine triphosphatase copper‐transporting beta (ATP7B); however, genetic testing identifies only one or no pathogenic ATP7B variant in a number of patients with WD.
Marlene Panzer, André Viveiros, Benedikt Schaefer, Nadja Baumgartner, Klaus Seppi, Atbin Djamshidian, Theodor Todorov, William J. H. Griffiths, Eckart Schott, Markus Schuelke, Dennis Eurich, Albert Friedrich Stättermayer, Adrian Bomford, Pierre Foskett, Julia Vodopiutz, Rudolf Stauber, Elke Pertler, Bernhard Morell, Herbert Tilg, Thomas Müller, Stefan Kiechl, Raul Jimenez‐Heredia, Karl Heinz Weiss, Si Houn Hahn, Andreas Janecke, Peter Ferenci, Heinz Zoller   +26 more
doaj   +1 more source

Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]

, 2013
<p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J., Engelsma, M.Y., Peeters, B.P.H., Rottier, P.J.M., van Beurden, S.J.   +4 more
core   +3 more sources

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Characterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart

JACC: Basic to Translational Science, 2023
Summary: Whereas adrenergic stimulation promotes cardiac function that demands more fuel and energy, how this receptor controls cardiac glucose metabolism is not defined.
Aleksandra Jovanovic, PhD, Bing Xu, BS, Chaoqun Zhu, PhD, Di Ren, PhD, Hao Wang, PhD, Meredith Krause-Hauch, PhD, E. Dale Abel, PhD, MD, Ji Li, PhD, Yang K. Xiang, PhD   +8 more
doaj   +1 more source

1‐Methylcyclopropene Containing‐Paper Enhances the Storability of Anxi Persimmon by Regulating Energy Metabolism

Future Postharvest and Food, EarlyView.
1‐Methylcyclopropene (1‐MCP) containing‐paper delayed the color change and maintained higher rate of commercially acceptable fruit in Anxi persimmons during storage were attributed to the increased activities of H+‐ATPase, Ca2+‐ATPase, and Mg2+‐ATPase and higher levels of ATP content and energy charge (EC).
Lingzhen Zeng, Lili Shi, Yuzhao Lin, Yixiong Lin, Hetong Lin, Hui Wang   +5 more
wiley   +1 more source