Results 61 to 70 of about 67,703 (305)

Xylose Metabolism Perturbation in Yarrowia lipolytica for Efficient Succinic Acid Bioproduction from Lignocellulosic Biomass

open access: yesAdvanced Science, EarlyView.
This study engineers Yarrowia lipolytica to produce succinic acid (SA) from lignocellulosic biomass. Adaptive evolution and multi‐omics analysis identify regulators that alleviate xylose metabolic disorder. Multi‐copy integration of xylose metabolic genes resolves redox imbalances from a futile fatty acid cycle, producing high‐titer SA from corn stover
Yutao Zhong   +7 more
wiley   +1 more source

Effect of Ginkgo Biloba Extract 50 on Immunity and Antioxidant Enzyme Activities in Ischemia Reperfusion Rats

open access: yesMolecules, 2011
The aim of the study was to investigate the effect of Ginkgo biloba extract 50 (GBE50), a well-known natural antioxidant, against immunity and antioxidant enzyme activities in ischemia reperfusion (IR) rats. Rats were then divided into six groups fed for
Xia Guo, Pinting Zhao, Shaoping Lu
doaj   +1 more source

Rho GTPase signaling in rheumatic diseases

open access: yesiScience, 2022
Summary: Rho guanosine triphosphatase (GTPases), as molecular switches, have been identified to be dysregulated and involved in the pathogenesis of various rheumatic diseases, mainly including rheumatoid arthritis, osteoarthritis, systemic sclerosis, and
Ruijie Zeng   +4 more
doaj   +1 more source

36 degree step size of proton-driven c-ring rotation in FoF1-ATP synthase [PDF]

open access: yes, 2009
Synthesis of the biological "energy currency molecule" adenosine triphosphate ATP is accomplished by FoF1-ATP synthase. In the plasma membrane of Escherichia coli, proton-driven rotation of a ring of 10 c subunits in the Fo motor powers catalysis in the ...
Boersch, Michael   +6 more
core   +2 more sources

Kinetics and regulation of the myofibrillar adenosine triphosphatase [PDF]

open access: yesBiochemical Journal, 1978
1. The steady-state kinetic behaviour of the ATPase (adenosine triphosphatase) of intact myofibrils was studied in the presence of both high and low concentrations of Ca2+ (0.25 mM and less than 10 nM respectively). 2. Kinetic data were collected over the initial linear phase of the assay, which lasts for 20–60s.
C M Wall, S V Perry, C C Goodno
openaire   +3 more sources

DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex

open access: yesAdvanced Science, EarlyView.
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang   +13 more
wiley   +1 more source

Comprehensive characterization of donkey milk serum proteins

open access: yesJournal of Future Foods, 2022
Donkey milk (DM) has attracted immense attention owing to its resemblance to human milk. Consequently, its components require rigorous analysis. This study aimed to identify DM serum proteins (DMSPs) using a label-free MS-based proteomics method. Herein,
Mohan Li   +5 more
doaj   +1 more source

An Mg2+ and Ca2+‐Stimulated Adenosine Triphosphatase in Human Prostatic Fluid: Part I

open access: yesAndrologia, 2009
Zusammenfassung Es wird uber die Enzym-Aktivitat eines Mg2+ und Ca2+-abhangigen ATPase-Enzym-systems berichtet, die an eine subzellulare Organelle geknupft und in der Prostata-Flus-sigkeit und damit im Seminalplasma vorhanden ist.
G. Ronquist   +3 more
semanticscholar   +1 more source

Distinct Phage‐Encoded Enzymes for Substitution of Deoxythymidine by Deoxyuridine in Phage Genomes

open access: yesAdvanced Science, EarlyView.
Distinct enzymes including dCTP deaminases (Dcds), dTMP phosphatases (Dtms), and dTTP pyrophosphatases (Dtt) are found to be responsible for dU‐DNA biosynthesis in the phages PBS1, DSS3_VP1, and PhiR1‐37. Both PhiR1‐37‐derived and synthetic dU‐DNA are resistant to cleavage by restriction enzymes and Cas12a nuclease targeting dT‐containing sites.
Yating Li   +7 more
wiley   +1 more source

Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]

open access: yes, 2013
<p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J.   +4 more
core   +3 more sources

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