Results 81 to 90 of about 56,477 (262)
Advanced Science, Volume 13, Issue 3, 14 January 2026.This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang +13 more
wiley +1 more source
Modulation of the asymmetry of sea urchin sperm flagellar bending by calmodulin [PDF]
, 1985 Sea urchin spermatozoa demembranated with Triton X-100 in the presence of EGTA, termed potentially asymmetric, generate asymmetric bending waves in reactivation solutions containing EGTA. After they are converted to the potentially symmetric condition by
Brokaw, C. J., Nagayama, S. M.
core +2 more sources
Reinforcement Learning for Robust Dynamic Metabolic Control
Biotechnology and Bioengineering, Volume 123, Issue 1, Page 79-91, January 2026.ABSTRACT Dynamic metabolic control allows key metabolic fluxes to be modulated in real time, enhancing bioprocess flexibility and expanding available optimization degrees of freedom. This is achieved, for example, via targeted modulation of metabolic enzyme expression.
Sebastián Espinel‐Ríos +2 more
wiley +1 more source
Protein & Cell, 2015 Cell division and expansion require the ordered arrangement of microtubules, which are subject to spatial and temporal modifications by developmental and environmental factors.
Qun Zhang, Wenhua Zhang
doaj +1 more source
Solving the Structure of eIF2 Bound to eIF2B Using Cryogenic Electron Microscopy [PDF]
, 2019 Translation begins when initiation factor-2 (eIF2) delivers methionyl initiator tRNA (Met-tRNAi) to the ribosome. The exchange of GDP bound to eIF2 for GTP is a prerequisite to binding Met-tRNAi and is mediated by a second initiation factor, eIF2B ...
Kenner, Lillian
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ChemMedChem, Volume 21, Issue 2, January 2026.5′ Cap modifications can be introduced via enzymes or chemical synthesis. Natural and non‐natural 5′ cap structures affect mRNA properties, including translation (T), stability (S), and/or immunogenicity (I). Eukaryotic mRNAs made by in vitro transcription have emerged as medical modalities for vaccination and protein replacement therapy. The 5′ cap is
Greta Charlotte Dahm +3 more
wiley +1 more source
BMC Infectious DiseasesBackground Globally, 80 million people are suffering from chronic Hepatitis C virus (HCV) infection. Sofosbuvir ribavirin-based anti-HCV therapy is associated with anemia and other adverse effects.
Sameen Amjed +6 more
doaj +1 more source
Biosystems Diversity, 2019 The activity of acid phosphatase, alkaline phosphatase and adenosine triphosphatase in the eccrine and sebaceous glands of the skin of the soles of the paws of male and female Norway rats was studied by histochemiсal methods.
A. B. Kiladze, N. K. Dzhemukhadze
doaj +1 more source
Specific nucleoside triphosphatases in crude extracts of escherichia coli [PDF]
General properties and distribution of nucleoside triphosphatases in crude extracts of Escherichia ...
Raacke, I. D.
core +1 more source
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus. [PDF]
, 2015 Viruses in the Reoviridae, like the triple-shelled human rotavirus and the single-shelled insect cytoplasmic polyhedrosis virus (CPV), all package a genome of segmented double-stranded RNAs (dsRNAs) inside the viral capsid and carry out endogenous ...
Chang, Winston +5 more
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