Results 151 to 160 of about 3,877 (200)

The RNA binding protein ZFP36L2 displays tissue-selective mRNA targeting in mice. [PDF]

RNA Biol
Stephenson GS, Fleifel D, Cook JG, Laederach A, Ramos SBV.   +4 more
europepmc   +1 more source

Dexamethasone inhibits the LPS-induced activation of hypoxia-inducible factor 1 alpha (HIF-1α) in macrophages independently of the DUSP1-p38-TTP-HIF-1α regulatory axis

Lockwood C, Daley KK, O’Neil JD, Heighes KJ, Clayton SA, Clark AR.   +5 more
europepmc   +1 more source

Review of roles of RNA-binding proteins on NAFLD and the related pharmaceutical measures. [PDF]

Biomol Biomed
Li C, Yang F, Yuan Z, Wei X.
europepmc   +1 more source

ZFP36L2 Is a Potential Prognostic Marker of IL1β⁺ Osteosarcoma. [PDF]

Biomedicines
Hao P, Luo P, Xu S, Ren Z, Zhao H, Nan X.   +5 more
europepmc   +1 more source

Restraint of inflammasome-driven cytokine responses through the mRNA stability protein TTP. [PDF]

Cell Rep
O'Keefe ME, Kondolf HC, De Santis S, Pizarro TT, Abbott DW.   +4 more
europepmc   +1 more source

Role of Gold in Inflammation and Tristetraprolin Activity

Chemistry - A European Journal, 2020
AbstractThe zinc finger protein tristetraprolin (TTP) regulates inflammation by downregulating cytokine mRNAs. Misregulation results in arthritis, sepsis and cancer, and there is an interest in modulating TTP activity with exogenous agents. Gold has anti‐inflammatory properties and has recently been shown to modulate the signaling pathway that produces
Kiwon Ok, Wenjing Li, Heather M Neu
exaly   +4 more sources

Roles of Tristetraprolin in Tumorigenesis [PDF]

International Journal of Molecular Sciences, 2018
Genetic loss or mutations in tumor suppressor genes promote tumorigenesis. The prospective tumor suppressor tristetraprolin (TTP) has been shown to negatively regulate tumorigenesis through destabilizing the messenger RNAs of critical genes implicated in both tumor onset and tumor progression.
Jeong-Min Park, Tae-Hee Lee, Tae-Hong Kang   +2 more
exaly   +3 more sources

Regulation of tristetraprolin during differentiation of 3T3-L1 preadipocytes [PDF]

FEBS Journal, 2007
Tristetraprolin is a zinc‐finger‐containing RNA‐binding protein. Tristetraprolin binds to AU‐rich elements of target mRNAs such as proto‐oncogenes, cytokines and growth factors, and then induces mRNA rapid degradation. It was observed as an immediate‐early gene that was induced in response to several kinds of stimulus, such as insulin and other growth ...
Chen-Si Lin, Ching-Jin Chang
exaly   +3 more sources

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Abstract P3179: Tristetraprolin Regulates Metabolic And Epigenetic Remodeling In Cardiomyocytes Post Myocardial Infarction

Circulation Research, 2023
Myocardial infarction (MI) triggers profound remodeling in the infarcted, border (BZ), and remote zones of the myocardium. Here, we studied the metabolic remodeling and epigenetic modifications that occur in response to inflammation in the BZ, focusing ...
A. Mahmoodzadeh, Ashley Akrami, M. Keykhaei, N. Koleini, H. Ardehali   +4 more
semanticscholar   +1 more source