Results 181 to 190 of about 3,877 (200)

Tristetraprolin recruits functional mRNA decay complexes to ARE sequences

Journal of Cellular Biochemistry, 2006
AbstractAU‐rich elements (AREs) in the 3′ untranslated region (UTR) of numerous mammalian transcripts function as instability elements that promote rapid mRNA degradation. Tristetraprolin (TTP) is an ARE‐binding protein that promotes rapid mRNA decay through mechanisms that are poorly understood.
Heidi H, Hau, Richard J, Walsh, Rachel L, Ogilvie, Darlisha A, Williams, Cavan S, Reilly, Paul R, Bohjanen   +5 more
openaire   +2 more sources

Tristetraprolin beyond cytokine mRNA decay

2020
Für die Aufrechterhaltung eines gesunden Körperzustandes ist eine strenge Regulation des Immunsystems erforderlich. Dabei ist Tristetraprolin (TTP) ein wichtiger Faktor, da es die mRNA von Zytokinen und Chemokinen destabilisiert, wodurch es zum Abklingen der Entzündung und zur Wiederherstellung der Immunhomöostase kommt.
openaire   +1 more source

Su1279: DECIPHERING THE MECHANISM BY WHICH RNA-BINDING PROTEIN, TRISTETRAPROLIN (TTP), CONTROLS BARRIER FUNCTION IN THE INTESTINAL EPITHELIUM

Gastroenterology
M. Brewer, Melanie A. Eshelman
semanticscholar   +1 more source

Pb(II) coordination to the nonclassical zinc finger tristetraprolin: retained function with an altered fold

JBIC Journal of Biological Inorganic Chemistry, 2022
Andrew T. Stoltzfus, Courtney Campbell, Madison M Worth, K. Hom, Timothy L. Stemmler, S. Michel   +5 more
semanticscholar   +1 more source

Tristetraprolin

2018
openaire   +1 more source

Tristetraprolin (TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals

Modern Rheumatology, 2008
Akito Tsutsumi, Hiroyuki Suzuki, Makoto Sugihara   +2 more
exaly  

Tristetraprolin inhibits HIV-1 production by binding to genomic RNA

Microbes and Infection, 2006
Hirofumi Sawa, Minoru Tobiume, Kenzo Tokunaga   +2 more
exaly  

Tristetraprolin (TTP)

2008
openaire   +1 more source

Bi-phased regulation of the post-transcriptional inflammatory response by Tristetraprolin levels

RNA Biology, 2019
Linah Mahmoud, Khalid S A Khabar, Edward Hitti   +2 more
exaly  

Phosphorylation site analysis of the anti-inflammatory and mRNA-destabilizing protein tristetraprolin

Expert Review of Proteomics, 2007
Heping Cao, Leesa J Deterding, Perry J Blackshear   +2 more
exaly