Alkaline water modules the expression of inflammation genes: in vitro model for cancer prevention [PDF]
World Cancer Research Journal, 2020 OBJECTIVE: Many researches focus their attention on the behavior of cells to specific substances with alkalizing power. Each substance that we introduce with food, as well as water, contributes to conditioning the electrophilic balance (acid-base) of the
A. Del Buono +5 more
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pH-sensing G protein-coupled orphan receptor GPR68 is expressed in human cartilage and correlates with degradation of extracellular matrix during OA progression [PDF]
PeerJ, 2023 Background Osteoarthritis (OA) is a debilitating joints disease affecting millions of people worldwide. As OA progresses, chondrocytes experience heightened catabolic activity, often accompanied by alterations in the extracellular environment’s ...
Nazir M. Khan +5 more
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Phenolic metabolites of anthocyanins modulate mechanisms of endothelial function [PDF]
, 2015 Anthocyanins are reported to have vascular bioactivity, however their mechanisms of action are largely unknown. Evidence suggests that anthocyanins modulate endothelial function, potentially by increasing nitric oxide (NO) synthesis, or enhancing NO ...
Cassidy, Aedin +4 more
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Comparative analysis of the toxicity of gold nanoparticles in zebrafish [PDF]
, 2018 The use of nanoparticles - particles that range in size from 1 to 100 nanometres - has become increasingly prevalent in recent years, bringing with it a variety of potential toxic effects.
Abdal Dayem +31 more
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Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer
Biomedicines, 2021 MiRNAs play a relevant role in PC (prostate cancer) by the regulation in the expression of several pathways’ AR (androgen receptor), cellular cycle, apoptosis, MET (mesenchymal epithelium transition), or metastasis.
Luis Javier Martínez-González +8 more
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eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts [PDF]
, 2016 Background: We have previously shown that the eukaryotic elongation factor subunit 1B gamma (eEF1Bγ) interacts with the RNA polymerase II (pol II) alpha-like subunit “C” (POLR2C), alone or complexed, in the pol II enzyme. Moreover, we demonstrated that
Ammassari-teule, Martine +9 more
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High-quality RNA extraction from the sea urchin Paracentrotus lividus embryos. [PDF]
PLoS ONE, 2017 The sea urchin Paracentrotus lividus (Lamarck, 1816) is a keystone herbivore in the Mediterranean Sea due to its ability to transform macroalgal-dominated communities into barren areas characterized by increased cover of bare substrates and encrusting ...
Nadia Ruocco +6 more
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Inactivation of Material from SARS-CoV-2-Infected Primary Airway Epithelial Cell Cultures
Methods and Protocols, 2021 Given that the airway epithelium is the initial site of infection, study of primary human airway epithelial cells (AEC) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will be crucial to improved understanding of viral entry ...
Kaitlyn A. Barrow +6 more
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Genome-Wide Association Study and Subsequent Exclusion of ATCAY as a Candidate Gene Involved in Equine Neuroaxonal Dystrophy Using Two Animal Models. [PDF]
, 2020 Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder of unknown etiology. Clinical signs of neurological deficits develop within the first year of life in vitamin E (vitE) deficient ...
Dahlgren, Anna R +6 more
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Memorias do Instituto Oswaldo Cruz, 2010 This study aimed to quantify Toxoplasma gondii in tissue samples of serologically positive chickens using real-time polymerase chain reaction (PCR). Of 65 chickens evaluated, 28 were positive for T. gondii antibodies.
Cleiton Paulo Aigner +5 more
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