pH-sensing G protein-coupled orphan receptor GPR68 is expressed in human cartilage and correlates with degradation of extracellular matrix during OA progression [PDF]
PeerJ, 2023 Background Osteoarthritis (OA) is a debilitating joints disease affecting millions of people worldwide. As OA progresses, chondrocytes experience heightened catabolic activity, often accompanied by alterations in the extracellular environment’s ...
Nazir M. Khan +5 more
doaj +2 more sources
eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts [PDF]
, 2016 Background: We have previously shown that the eukaryotic elongation factor subunit 1B gamma (eEF1Bγ) interacts with the RNA polymerase II (pol II) alpha-like subunit “C” (POLR2C), alone or complexed, in the pol II enzyme. Moreover, we demonstrated that
Ammassari-teule, Martine +9 more
core +1 more source
Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer
Biomedicines, 2021 MiRNAs play a relevant role in PC (prostate cancer) by the regulation in the expression of several pathways’ AR (androgen receptor), cellular cycle, apoptosis, MET (mesenchymal epithelium transition), or metastasis.
Luis Javier Martínez-González +8 more
doaj +1 more source
High-quality RNA extraction from the sea urchin Paracentrotus lividus embryos. [PDF]
PLoS ONE, 2017 The sea urchin Paracentrotus lividus (Lamarck, 1816) is a keystone herbivore in the Mediterranean Sea due to its ability to transform macroalgal-dominated communities into barren areas characterized by increased cover of bare substrates and encrusting ...
Nadia Ruocco +6 more
doaj +1 more source
Mortality associated with avian reovirus infection in a free-living magpie (Pica pica) in Great Britain [PDF]
, 2015 Avian reoviruses (ARVs) cause a range of disease presentations in domestic, captive and free-living bird species. ARVs have been reported as a cause of significant disease and mortality in free-living corvid species in North America and continental ...
Cunningham, AA +9 more
core +1 more source
Inactivation of Material from SARS-CoV-2-Infected Primary Airway Epithelial Cell Cultures
Methods and Protocols, 2021 Given that the airway epithelium is the initial site of infection, study of primary human airway epithelial cells (AEC) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will be crucial to improved understanding of viral entry ...
Kaitlyn A. Barrow +6 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2010 This study aimed to quantify Toxoplasma gondii in tissue samples of serologically positive chickens using real-time polymerase chain reaction (PCR). Of 65 chickens evaluated, 28 were positive for T. gondii antibodies.
Cleiton Paulo Aigner +5 more
doaj +1 more source
Molecular characterization of cDNA encoding resistance gene-like sequences in Buchloe dactyloides [PDF]
, 2006 Current knowledge of resistance (R) genes and their use for genetic improvement in buffalograss (Buchloe dactyloides [Nutt.] Engelm.) lag behind most crop plants.
Budak, Hikmet +7 more
core +1 more source
Plants, 2013 Jerusalem artichoke (Helianthus tuberosus L.) is an important tuber crop. However, Jerusalem artichoke seeds contain high levels of starch and lipid, making the extraction of high-quality RNA extremely difficult and the gene expression analysis ...
Tanupat Mornkham +5 more
doaj +1 more source
Genome-Wide Association Study and Subsequent Exclusion of ATCAY as a Candidate Gene Involved in Equine Neuroaxonal Dystrophy Using Two Animal Models. [PDF]
, 2020 Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder of unknown etiology. Clinical signs of neurological deficits develop within the first year of life in vitamin E (vitE) deficient ...
Dahlgren, Anna R +6 more
core +1 more source