Results 41 to 50 of about 27,805 (268)

Bond between textile reinforced mortar (TRM) and concrete substrate [PDF]

open access: yes, 2017
There is a growing interest for strengthening and upgrading existing concrete structures both in seismic and non-seismic regions due to their continuous deterioration as a result of aging, degradation induced environment conditions, inadequate ...
Raoof, Saad Mahmood
core  

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian   +8 more
wiley   +1 more source

Pulmonary resident memory T cells in respiratory virus infection and their inspiration on therapeutic strategies

open access: yesFrontiers in Immunology, 2022
The immune system generates memory cells on infection with a virus for the first time. These memory cells play an essential role in protection against reinfection.
Meng Zhang   +5 more
doaj   +1 more source

Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception

open access: yesAdvanced Science, EarlyView.
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng   +7 more
wiley   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

open access: yesAdvanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li   +9 more
wiley   +1 more source

EXTRACTION OF ON-BOARD TRM HIGH-POWER MICROWAVE HEMT PARAMETERS

open access: yesНаучный вестник МГТУ ГА, 2016
Analytical nonlinear model of high-power microwave HEMT with parallel resonance circuits was designed. Extraction method of high-power HEMT parameters without optimization usage was proposed and described. Test board for high-power HEMT measurement for 0.
R. Yu. Malakhov
doaj  

CD69+CD103+CD8+ tissue-resident memory T cells possess stronger anti-tumor activity and predict better prognosis in colorectal cancer

open access: yesCell Communication and Signaling
Background Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. Despite advancements in therapeutic methodologies, it still causes a high rate of patient mortality. CD8+ tissue-resident memory T (TRM) cells are strategically positioned
Zi-Xin Wu   +11 more
doaj   +1 more source

Energy Efficiency Alberta TRM Introduction [PDF]

open access: yes, 2020
This document is intended to provide a high-level understanding of the Energy Efficiency Alberta Technical Reference Manual (TRM), including background, how it was constructed, its intended use and general guidelines for maintenance and further ...
Energy Efficiency Alberta
core   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu   +15 more
wiley   +1 more source

Bond between textile reinforced mortar (TRM) and concrete substrate [PDF]

open access: yes
There is a growing interest for strengthening and upgrading existing concrete structures both in seismic and non-seismic regions due to their continuous deterioration as a result of aging, degradation induced environment conditions, inadequate ...
Raoof, Saad Mahmood
core   +3 more sources

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