Results 161 to 170 of about 4,753,527 (236)

037 CD4+CD103+ cutaneous TRM cells are found in the circulation of healthy humans [PDF]

Journal of Investigative Dermatology, 2019
P. Morawski, S. Varkhande, M. Klicznik, B. Hoellbacher, S. Motley, I. Gratz, D. Campbell   +6 more
openaire   +1 more source

Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells

, 2016
Tissue-resident memory T cells (TRM cells) in the airways mediate protection against respiratory infection. We characterized TRM cells expressing integrin αE (CD103) that reside within the epithelial barrier of human lungs.
Nota, Benjamin, Clevers, Hans C, Backer, Ronald A, Stark, Regina, Brasser, Giso, Oja, Anna E, Amsen, Derk, Piet, Berber, Hombrink, Pleun, Jongejan, Aldo, Jonkers, René E, van Lier, René A W, Helbig, Christina, Basak, Onur, Moerland, Perry D, CMM Sectie Molecular Cancer Research, Regenerative Medicine and Stem Cells, Brain, Divisie LAB, Child Health, Hubrecht Institute with UMC, Cancer   +21 more
core  

NGO ameliorates psoriasis by modulating mitochondrial function and suppressing pSTAT3-IL-17-expressing CD8⁺ TRM cells. [PDF]

J Nanobiotechnology
Kim TH, Lee CR, Choi KM, Choi SW, Lee SY, Lee AR, Choi JW, Moon YM, Park J, Choi H, Ryu J, Bang CH, Cho ML.   +12 more
europepmc   +1 more source

CCR2 restricts IFN-γ production by hippocampal CD8 TRM cells that impair learning and memory during recovery from WNV encephalitis. [PDF]

J Neuroinflammation
Ai S, Arutyunov A, Liu J, Hill JD, Jiang X, Klein RS.   +5 more
europepmc   +1 more source

Early RSV infection aggravates asthma-related Th2 responses by increasing the number of CD4 ⁺ TRM cells through upregulation of PLZF. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Zhang M, Sha J, Li N, Feng J, Shi T, Yu Y, Ren X, Mei Z, Jie Z.   +8 more
europepmc   +1 more source

Role of mucosal chemokines in the development of tissue-resident CD4⁺ and CD8⁺ T_RM cells to fend off herpes simplex infections. [PDF]

Front Immunol
Lekbach Y, Chentoufi AA, Prakash S, Karan S, Quadiri A, Hormi-Carver KK, Dorotta JC, BenMohamed L.   +7 more
europepmc   +1 more source

CCL25 chemokine promotes antiviral tissue resident CD4⁺ and CD8⁺ effector memory T_RM cells associated with a reduction of ocular herpes infection and disease: a potential gut-eye axis in herpes immunity. [PDF]

Front Immunol
Rahman A, Prakash S, Karan S, Ng SXL, Park G, Maurya C, Garcia A, Intharachalit K, Hwang J, Tang CTY, Chow RA, Suoth BS, Liao EJ, BenMohamed L.   +13 more
europepmc   +1 more source

Therapeutic mucosal vaccination of herpes simplex virus type 2 infected guinea pigs with an adenovirus-based vaccine expressing the ribonucleotide reductase 2 and glycoprotein D induces local tissue-resident CD4+ and CD8+ TRM cells associated with protection against recurrent genital herpes. [PDF]

Front Immunol
Quadiri A, Prakash S, Vahed H, Tadros JM, Sun M, Hormi-Carver KK, Patel SJ, BenMohamed L.   +7 more
europepmc   +1 more source

Foxo1 regulates synovial CD8+ TRM formation in a mouse model of inflammatory arthritis

Tissue-resident memory T cells (TRM) are a subset of CD8+ T cells that settle in the peripheral tissues after encountering antigens. TRM can initiate rapid immune response to antigens they have encountered and provide long-lasting protection at the local
Sun, Lixin
core  

Protecting against malaria through liver-resident memory T cells

We have shown that formation of liver-resident memory T cells (Trm), a newly discovered type of immune cells, can be induced by an innovative vaccination strategy called prime and trap for highly efficient protection against malaria in mice.

core   +1 more source