Results 111 to 120 of about 36,147 (195)

Phenotypic Florfenicol Resistance in floR‐Harbouring Flavobacterium psychrophilum Isolates (CC‐ST90): A Case Study From Danish Freshwater Rainbow Trout Aquaculture

Journal of Fish Diseases, EarlyView.
ABSTRACT Monitoring antimicrobial resistance (AMR) in fish pathogens is essential for supporting sustainable aquaculture. In this study, susceptibility testing and genome sequencing were used to characterize the AMR profile of seven Flavobacterium psychrophilum originating from Danish rainbow trout farms (2019–2022).
Valentina L. Donati, Lone Madsen
wiley   +1 more source

tRNA-derived small RNAs in plant response to biotic and abiotic stresses. [PDF]

Front Plant Sci, 2023
Wang C, Chen W, Aili M, Zhu L, Chen Y.
europepmc   +1 more source

Enhanced exonuclease–Cas9 systems promote multiple nucleotide deletions with higher efficiency and broader targeting scope in plants

Journal of Integrative Plant Biology, EarlyView.
Cas9 preferentially generates small indels. By tethering an exonuclease and a DNA‐binding domain (DBD) to Cas9, the Exo‐DBD‐Cas9 system efficiently promotes multiple nucleotide deletions. These expanded deletions enable effective disruption of miRNA‐mediated regulation and relieve translational repression through targeted editing of 3′ untranslated ...
Rui Zhang, Xu Tang, Yao He, Wei Wang, Qiurong Ren, Yiping Qi, Yong Zhang   +6 more
wiley   +1 more source

The Emerging Role of tRNA-Derived Small RNAs (tsRNAs) in Radiation-Induced Cardiovascular Pathology [PDF]

Endocr Metab Immune Disord Drug Targets
Chen Y, Zhu Y, Qian L, Hu Q.
europepmc   +1 more source

Expression profiles and functional analysis of tRNA-derived small RNAs in epicardial adipose tissue of patients with heart failure. [PDF]

Ann Med, 2023
Zhao L, Peng Y, Su P.
europepmc   +1 more source

Optimized TadA‐derived base editors efficiently manipulate mRNA splicing by A‐to‐G and C‐to‐K editing in potato

Journal of Integrative Plant Biology, EarlyView.
Two optimized TadA‐derived base editors efficiently generate diverse splicing variants by targeting specific splice sites in potato. ABSTRACT Pre‐messenger RNA (pre‐mRNA) splicing is a critical mechanism for post‐transcriptional regulation in plants. Through alternative splicing, plants produce diverse transcriptomes and proteomes that finely regulate ...
Kaiyuan Chen, Yan Zhang, Jiuzhou Deng, Lumin Zhang, Huiying Zhou, Yaxin Duan, Enle Xiao, Guangtao Zhu, Chunzhi Zhang   +8 more
wiley   +1 more source

Uncovering the role of the PPR protein PHOTOSYSTEM ONE BIOGENESIS FACTOR6 in splicing chloroplast group II introns

Journal of Integrative Plant Biology, EarlyView.
The P‐class pentatricopeptide repeat (PPR) protein PHOTOSYSTEM ONE BIOGENESIS FACTOR (PBF6) forms splicing complexes with other known splicing factors to facilitate chloroplast intron splicing. PBF6 cooperates with other PPR splicing factors to promote the splicing of the same intron through forming respective splicing complexes.
Mengyu Li, Mengwei Sun, Jinlian Lv, Mingming Song, Siyu Lu, Aihong Zhang, Congming Lu   +6 more
wiley   +1 more source

A novel Cas12b cytosine base editor enables efficient C‐to‐T base editing in the rice genome

Journal of Integrative Plant Biology, EarlyView.
The base editor dAaCas12b accurately induces C‐to‐T mutations in rice. It recognizes unique TTTV DNA motifs with a wider editing window, and its optimized guide RNA boosts efficiency, expanding crop gene‐editing resources.
Yulei Wei, Lin He, Jienan Han, Shengnan Ge, Xueheyuan Wang, Xinyu Liu, Jie Deng, Haiyang Zhang, Xinyang Che, Jianfeng Weng, Wujun Ma, Jingyu Xu   +11 more
wiley   +1 more source

Biological roles and potential clinical value of tRNA-derived small RNAs in gastrointestinal malignancies. [PDF]

Ann Med
Shao Y, Yu X, Zhou W, Yan J, Dong H, Ye G.   +5 more
europepmc   +1 more source

Differential expression spectrum and targeted gene prediction of tRNA-derived small RNAs in idiopathic pulmonary arterial hypertension. [PDF]

Front Mol Biosci, 2023
Chen Y, Tang Y, Hou S, Luo J, Chen J, Qiu H, Chen W, Li K, He J, Li J.   +9 more
europepmc   +1 more source