Results 1 to 10 of about 1,504 (112)
Transfer RNA-derived small RNAs (tsRNAs) in gastric cancer
Frontiers in Oncology, 2023 Transfer RNA-derived small RNAs (tsRNAs) are newly discovered noncoding RNAs (ncRNAs). According to the specific cleavage of nucleases at different sites of tRNAs, the produced tsRNAs are divided into tRNA-derived stress-inducible RNAs (tiRNAs) and tRNA ...
Xiaoyun Ding, Lu Gan, Ding Xiaoyun
exaly +3 more sources
Transfer RNA-derived small RNAs as novel players and biomarkers in cardiovascular disease [PDF]
Cardiology JournalAn emerging field in cardiovascular research is the translational investigation of transfer RNA-derived small RNAs (tsRNAs). TsRNAs, a class of small non-coding RNA molecules, have been shown to modulate cellular functions by regulating gene expression ...
Qiuwang Zhang +3 more
doaj +2 more sources
Altered expression spectrum and target gene prediction of tRNA-derived small RNAs in clear cell renal cell carcinoma [PDF]
BMC CancerBackground Dysregulation of tRNA-derived small RNAs (tsRNAs) in various cancers has been indicated to play vital roles in tumorigenesis, but few reported in clear cell renal cell carcinoma (ccRCC).
Shuai Liu +15 more
doaj +2 more sources
Metazoan tsRNAs: Biogenesis, Evolution and Regulatory Functions
Non-coding RNA, 2019 Transfer RNA-derived small RNAs (tsRNAs) are an emerging class of regulatory non-coding RNAs that play important roles in post-transcriptional regulation across a variety of biological processes.
Yirong Wang, Jian Lu, Shengqian Dou
exaly +3 more sources
Biological roles and potential clinical value of tRNA-derived small RNAs in gastrointestinal malignancies [PDF]
Annals of MedicinetRNA-derived small RNAs (tsRNAs) are small RNA fragments generated from tRNA molecules or their precursors through cleavage by enzymes such as Dicer. As noncoding small RNAs, tsRNAs have important biological functions, including regulating mRNA stability
Yongfu Shao +5 more
doaj +2 more sources
The 3’tsRNAs are aminoacylated: Implications for their biogenesis
PLoS Genetics, 2021 Emerging evidence indicates that tRNA-derived small RNAs (tsRNAs) are involved in fine-tuning gene expression and become dysregulated in various cancers.
Mark Kay, Hak Kyun, Ziwei Liu
exaly +2 more sources
Screening and Functional Analysis of tsRNAs Associated with Diabetic Foot Ulcer Tissues [PDF]
BiomedicinesBackground: Diabetic foot ulcer (DFU) is a serious complication of diabetes mellitus, and its inability to heal is closely linked to vascular pathology. However, the specific molecular regulatory networks involved remain unclear.
Xiaona He +8 more
doaj +2 more sources
Npj Breast Cancer, 2021 Liquid biopsy is noninvasive and convenient to detect cancer-derived materials in blood or other body fluids. The aim of this study was to identify tRNA-derived small RNAs (tsRNAs) in plasma that could distinguish patients with breast cancer (BC) from ...
Xiaoan Liu, Shui Wang, Tiansong Xia
exaly +2 more sources
Frontiers in Molecular Biosciences, 2023 Background: Idiopathic pulmonary arterial hypertension (PAH) is a potentially fatal pulmonary vascular disease with an extremely poor natural course. The limitations of current treatment and the unclear etiology and pathogenesis of idiopathic PAH require
Yusi Chen +9 more
doaj +1 more source
tRNA-derived small RNAs in plant response to biotic and abiotic stresses
Frontiers in Plant Science, 2023 tRNA-derived small RNAs (tsRNAs) represent a novel category of small non-coding RNAs and serve as a new regulator of gene expression at both transcriptional and post-transcriptional levels. Growing evidence indicates that tsRNAs can be induced by diverse
Chaojun Wang +5 more
doaj +1 more source