Results 101 to 110 of about 298,923 (289)

Multiple Layers of Stress-Induced Regulation in tRNA Biology

open access: yesLife, 2016
tRNAs are the fundamental components of the translation machinery as they deliver amino acids to the ribosomes during protein synthesis. Beyond their essential function in translation, tRNAs also function in regulating gene expression, modulating ...
Hsiao-Yun Huang, Anita K. Hopper
doaj   +1 more source

Conserved Amino Acids in Each Subunit of the Heteroligomeric tRNA m\u3csup\u3e1\u3c/sup\u3eA58 Mtase from \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e Contribute to tRNA Binding [PDF]

open access: yes, 2007
In Saccharomyces cerevisiae, a two-subunit methyltransferase (Mtase) encoded by the essential genes TRM6 and TRM61 is responsible for the formation of 1-methyladenosine, a modified nucleoside found at position 58 in tRNA that is critical for the ...
Anderson, James T.   +3 more
core   +1 more source

Determination of selenium speciation in the muscle, kidney, and liver from different animals treated with different selenium supplements by HPLC‐ICP‐MS

open access: yesAnimal Research and One Health, EarlyView.
Dietary selenium (Se) deficiency is recognized as a global problem, and exogenous Se supplementation can effectively enrich its levels in animal bodies. Offal tissues are equally important as meat in Se enrichment. Varying properties among Se species require information beyond total Se concentration to fully evaluate health risk/benefits.
Xiaoqing Guo   +9 more
wiley   +1 more source

Role of RNA modifications in carcinogenesis and carcinogen damage response

open access: yesMolecular Carcinogenesis, Volume 62, Issue 1, Page 24-37, January 2023., 2023
Abstract The field of epitranscriptomics encompasses the study of post‐transcriptional RNA modifications and their regulatory enzymes. Among the numerous RNA modifications, N6‐methyladenosine (m6A) has been identified as the most common internal modification of messenger RNA (mRNA).
Michelle Verghese   +2 more
wiley   +1 more source

Rosmarinic Acid Alleviates Radiation-Induced Pulmonary Fibrosis by Downregulating the tRNA N7-Methylguanosine Modification-Regulated Fibroblast-to-Myofibroblast Transition Through the Exosome Pathway

open access: yesJournal of Inflammation Research
Tingting Zhang,1– 3,* Jinglin Mi,1– 3,* Xinling Qin,1– 3,* Zhechen Ouyang,1– 3 Yiru Wang,1– 3 Zhixun Li,1– 3 Siyi He,1– 3 Kai Hu,1– 3 Rensheng Wang,1– 3 Weimei Huang1– 3 1Department of Radiation Oncology, the First Affiliated Hospital of ...
Zhang T   +9 more
doaj  

Nuclear and mitochondrial tRNA-lookalikes in the human genome

open access: yesFrontiers in Genetics, 2014
We are interested in identifying and characterizing loci of the human genome that harbor sequences resembling known mitochondrial and nuclear tRNAs. To this end, we used the known nuclear and mitochondrial tRNA genes (the tRNA-Reference set) to search ...
Aristeidis G Telonis   +3 more
doaj   +1 more source

Expert Perspective: Diagnostic Approach to Differentiating Juvenile Dermatomyositis From Muscular Dystrophy

open access: yesArthritis &Rheumatology, EarlyView.
Clinical tools that can aid in the diagnostic differentiation of juvenile dermatomyositis from muscular dystrophy.
Jacqueline A. Madison   +9 more
wiley   +1 more source

Konstrukční výzkum (design-based research) v přírodovědných didaktikách

open access: yesScientia in Educatione, 2013
Teoretická studie s praktickou ukázkou prezentuje konstrukční výzkum (angl. design-based research) v přírodovědných didaktikách. V první části jsou vymezeny pojmy konstrukční přístup a konstrukční výzkum. Konstrukční výzkum je novým trendem v didaktickém
Josef Trna
doaj  

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