Results 131 to 140 of about 45,835 (226)

RNA‐Guided Engineering of the Chloroplast Genome Enabled by Plastid‐Expressed Guide RNAs

Plant Biotechnology Journal, EarlyView.
ABSTRACT Our goal is to develop RNA‐guided engineering of the chloroplast genome using the CRISPR/Cas9 system. We designed chloroplast minigenes to obtain properly sized single guide RNAs (sgRNAs) in tobacco chloroplasts. The sgRNA 5′ end is defined by transcription from an rRNA operon promoter, and its 3′ end by processing a downstream tRNA (trnG) or ...
Malihe Mirzaee, Corinne Best, Evelyn V. Wachowski, Pal Maliga   +3 more
wiley   +1 more source

Identification of Genetic Loci Conveying Resistance to Fusarium oxysporum f. sp. ciceris Race 0 in Chickpea

Plant Breeding, EarlyView.
ABSTRACT Chickpea (Cicer arietinum L.) is a legume that is widely consumed around the world due to its nutritional content. Fusarium oxysporum f. sp. ciceris is a serious, destructive pathogen that causes fusarium wilt disease and affects chickpea production.
Selda Kurt Ozyaramis, Talap Talapov, Canan Can, Muhammed Bahattin Tanyolac, Ahmed Rami al Saadi, Duygu Ates   +5 more
wiley   +1 more source

Characterization of tRNA-Derived Fragments in Lung Squamous Cell Carcinoma with Respect to Tobacco Smoke. [PDF]

Int J Mol Sci, 2023
Magesh S, Gande P, Yalamarty R, John D, Chakladar J, Li WT, Ongkeko WM.   +6 more
europepmc   +1 more source

Peripheral blood tRNA-derived fragments as novel noninvasive biomarkers for diagnosis and prognostic stratification in multiple myeloma. [PDF]

Front Immunol
Yi B, Gao Y, Huang Y, Guo K, Liu R, Zeng M, Xu H, Lei M.   +7 more
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Ovarian hormone loss modifies the nucleic acid cargo of circulating extracellular vesicles and skeletal muscle metabolism after acute exercise in rats

Experimental Physiology, EarlyView.
Abstract Loss of ovarian hormones (i.e., menopause) leads to negative effects on metabolic health. While exercise offers significant benefits, it seems to be insufficient to completely reverse these changes. The mechanisms by which exercise conveys the effects throughout the body are still poorly understood.
Veera Puumalainen, Anni Maja, Tia‐Marje Korhonen, Tuuli A. Nissinen, Eero Hulkko, Janne A. Ihalainen, Maarit Lehti, Sira Karvinen   +7 more
wiley   +1 more source

Plasma exosomal tRNA-derived fragments as diagnostic biomarkers in non-small cell lung cancer. [PDF]

Front Oncol, 2022
Zheng B, Song X, Wang L, Zhang Y, Tang Y, Wang S, Li L, Wu Y, Song X, Xie L.   +9 more
europepmc   +1 more source

Clinical Laboratory Innovations: Nanoscale Detection of Chloramphenicol Using Nanomaterial Biosensors

Analytical Science Advances, Volume 7, Issue 2, December 2026.
Nanosensor schematic functionalized with specific bioreceptors that produce electrochemical signals upon Chloramphenicol binding. Resulting voltammetric readouts (differential pulse, square‐wave, and cyclic voltammetry) are analyzed to identify and quantify Chloramphenicol.
Nava Moghadasian Niaki, Reza Kheradmand, Seyedeh Giso Akbarian, Elham Shaterian, Hamed Shaterian, Ahmad Mobed   +5 more
wiley   +1 more source

Dysregulated tRNA-derived fragments impair fatty acid metabolism in intrahepatic cholestasis of pregnancy. [PDF]

Front Med (Lausanne)
Yang L, Yu X, Zhang S, Fu J, Luo M, Shen W, Huang C, Yang X.   +7 more
europepmc   +1 more source

Maternal Serum tRNA-Derived Fragments (tRFs) as Potential Candidates for Diagnosis of Fetal Congenital Heart Disease. [PDF]

J Cardiovasc Dev Dis, 2023
Lu E, Wu L, Chen B, Xu S, Fu Z, Wu Y, Wu Y, Gu H.   +7 more
europepmc   +1 more source