Na+/K+ ATPase α1 and β3 subunits are localized to the basolateral membrane of trophectoderm cells in human blastocysts [PDF]
, 2022 Takeo Hirakawa +10 more
openalex +1 more source
Trophectoderm Biopsy: Present State of the Art
GenesTrophectoderm (TE) biopsy is at present the most widely used procedure for preimplantation genetic testing (PGT). At the blastocyst stage, more TE cells (five to seven) can be obtained for genetic analysis. While removing TE cells and not touching the inner cell mass (ICM), the procedure is less invasive.
Anick De Vos, Neelke De Munck
openaire +2 more sources
The Critical Role of GALNTs‐Regulated O‐GalNAc Glycosylation in Cancer Malignancy
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.The GALNT family initiates mucin‐type O‐GalNAc glycosylation in the Golgi apparatus and how regulatory mechanisms, including GALNT relocalization and microRNA control, modulate this process. Dysregulated O‐GalNAc glycosylation alters key cellular behaviors and promotes cancer malignancy, highlighting its relevance to tumor progression as well as its ...
Jiahao Liu +7 more
wiley +1 more source
Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin. [PDF]
PLoS Genetics, 2012 Insulin-like growth factor I receptor (Igf1r) signaling controls proliferation, differentiation, growth, and cell survival in many tissues; and its deregulated activity is involved in tumorigenesis.
Ivan Bedzhov +3 more
doaj +1 more source
Brg1 is required for Cdx2-mediated repression of Oct4 expression in mouse blastocysts.
PLoS ONE, 2010 During blastocyst formation the segregation of the inner cell mass (ICM) and trophectoderm is governed by the mutually antagonistic effects of the transcription factors Oct4 and Cdx2.
Kai Wang +5 more
doaj +1 more source
Increased dietary protein in the second trimester of gestation increases live weight gain and carcass composition in weaner calves to 6 months of age [PDF]
, 2017 Genetically similar nulliparous Polled Hereford heifers from a closed pedigree herd were used to evaluate the effects of dietary protein during the first and second trimester of gestation upon fetal, placental and postnatal growth.
Baur +55 more
core +2 more sources
P-228 Reliability of blastomere versus trophectoderm biopsy in preimplantation genetic testing for mitochondrial DNA disorders [PDF]
, 2023 Noemi Castelluccio +7 more
openalex +1 more source
Advanced Science, Volume 13, Issue 20, 9 April 2026.This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche +21 more
wiley +1 more source
Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo [PDF]
, 2014 A critical point in mammalian development is when the early embryo implants into its mother's uterus. This event has historically been difficult to study due to the fact that it occurs within the maternal tissue and therefore is hidden from view. In this
Bedzhov, Ivan +3 more
core +2 more sources
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, Volume 13, Issue 19, 2 April 2026.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source