Results 71 to 80 of about 22,216 (269)

Association of Trophectoderm mRNAs and MicroRNAs with Chromosomal Aneuploidy of Embryo

Reproductive Sciences, 2023
Abstract MicroRNAs (miRNAs) and mRNAs can serve as indicators of the chromosomal state of an embryo, with different profiles observed in euploid and aneuploid blastocysts. Examining the levels of miRNAs associated with aneuploidy and euploidy, as well as mRNAs related to implantation, can aid in predicting blastocyst chromosomal normality and ...
Masoumeh Esmaeilivand, Aliyeh Ghasemzadeh, Behrooz Niknafs, Amir Fattahi   +3 more
openaire   +2 more sources

Computer‐Assisted Sperm Analysis (CASA) Versus Manual Evaluation and the Clinical Significance of Sperm Hyperactivated Motility

Andrology, EarlyView.
Abstract Background Semen analysis remains the first‐line diagnostic test for male infertility, although it is affected by operator subjectivity. Computer‐assisted sperm analysis (CASA) is proposed to improve objectivity; however, its accuracy and clinical relevance remain uncertain.
Maria Emanuela Ragosta, Giulia Traini, Francesca Benini, Margherita Montereggi, Federica Bini, Lara Tamburrino, Linda Vignozzi, Elisabetta Baldi, Sara Marchiani   +8 more
wiley   +1 more source

The effects of aging on molecular modulators of human embryo implantation

iScience, 2021
Summary: Advancing age has a negative impact on female fertility. As implantation rates decline during the normal maternal life course, age-related, embryonic factors are altered and our inability to monitor these factors in an unbiased genome-wide ...
Panagiotis Ntostis, Grace Swanson, Georgia Kokkali, David Iles, John Huntriss, Agni Pantou, Maria Tzetis, Konstantinos Pantos, Helen M. Picton, Stephen A. Krawetz, David Miller   +10 more
doaj   +1 more source

Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos

Cell Proliferation, EarlyView.
Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang, Yan Zhang, Laijin Wu, Hongshuang Xie, Guang Yang, Yiwei Zhang, Cheng Huang, Shanyi Chou, Xuehan Li, Zhonghua Liu, Jiaqiang Wang   +10 more
wiley   +1 more source

Effect of Type of Culture Media on B6D2F1 Mice Oogenesis

Journal of Animal Reproduction and Biotechnology, 2016
This study was conducted to evaluate the effects of type of culture media (BM, G2, OS, TCM, and MEM) on B6D2F1 mice oogenesis. In the present study, B6D2F1/CrljOri F1 mice were utilized in order to maximize oogenesis.
Chang-Seok Yoo, Kee Sang Park, Byoung Boo Seo   +2 more
doaj   +1 more source

DISTINGUISHING MITOTIC AND MEIOTIC ORIGIN OF TRISOMY IN TROPHECTODERM BIOPSIES WITHOUT PARENTAL DNA [PDF]

, 2023
Bhavini Rana, Erik Widén, Diego Marín, Jia Xu, Nathan R. Treff   +4 more
openalex   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

Computational modelling unveils how epiblast remodelling and positioning rely on trophectoderm morphogenesis during mouse implantation.

PLoS ONE, 2021
Understanding the processes by which the mammalian embryo implants in the maternal uterus is a long-standing challenge in embryology. New insights into this morphogenetic event could be of great importance in helping, for example, to reduce human ...
Joel Dokmegang, Moi Hoon Yap, Liangxiu Han, Matteo Cavaliere, René Doursat   +4 more
doaj   +1 more source

The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice [PDF]

, 2013
DNA methylation plays an important role in suppressing retrotransposon activity in mammalian genomes, yet there are stages of mammalian development where global hypomethylation puts the genome at risk of retrotransposition-mediated genetic instability ...
Aravin, Baillie, Barbosa-Morais, Barrett, Beck, Bersinger, Bode, Bourc'his, Celebi, Chapman, Chen, Coan, David Read, de Koning, Diana Best, Du, Dupressoir, Finkenzeller, Fowden, Frost, Gabory, Gautier, Goodier, Hackett, Hackett, Haig, Hajkova, Hajkova, Horst, Hudson, Hutnick, Ian R. Adams, Jackson-Grusby, James P. Reddington, Ji, Judith Reichmann, Karimi, Krackow, Kumaki, Lander, Leeb, Ma, Maksakova, Mao, Martin, Mi, Mietz, Ono, Popp, R Development Core Team, Razin, Reichmann, Reik, Reiss, Reynolds, Richard R. Meehan, Rossant, Rowe, Rupert Öllinger, Salas, Santos, Schütt, Sekita, Shaut, Simmons, Simmons, Simmons, Singer, Smyth, Solyom, Thorrez, Tsumura, Tunster, Walsh, Watanabe, Waterston, Yang, Yoder, Zheng, Öllinger, Öllinger   +80 more
core   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source