Results 71 to 80 of about 15,306 (209)

Effect of Type of Culture Media on B6D2F1 Mice Oogenesis

Journal of Animal Reproduction and Biotechnology, 2016
This study was conducted to evaluate the effects of type of culture media (BM, G2, OS, TCM, and MEM) on B6D2F1 mice oogenesis. In the present study, B6D2F1/CrljOri F1 mice were utilized in order to maximize oogenesis.
Chang-Seok Yoo, Kee Sang Park, Byoung Boo Seo   +2 more
doaj   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

Association of Trophectoderm mRNAs and MicroRNAs with Chromosomal Aneuploidy of Embryo

Reproductive Sciences, 2023
Abstract MicroRNAs (miRNAs) and mRNAs can serve as indicators of the chromosomal state of an embryo, with different profiles observed in euploid and aneuploid blastocysts. Examining the levels of miRNAs associated with aneuploidy and euploidy, as well as mRNAs related to implantation, can aid in predicting blastocyst chromosomal normality and ...
Masoumeh Esmaeilivand, Aliyeh Ghasemzadeh, Behrooz Niknafs, Amir Fattahi   +3 more
openaire   +2 more sources

Single‐cell transcriptomic analysis reveals subtle fluctuations of oocyte cryopreservation on mouse early embryo development

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Mature oocytes were subjected to cryopreservation followed by intracytoplasmic sperm injection (ICSI). Embryos at multiple developmental stages were collected, dissociated into single cells and processed for single‐cell library construction and bioinformatics analysis.
Yixin Ren, Qingyang Zhang, Fanqing Xu, Yao Li, Tianyi Liao, Mengyuan Zhao, Zhiqiang Yan, Xiaohui Zhu, Nan Wang, Peng Yuan, Gary D Smith, Jie Qiao, Jie Yan, Liying Yan, Qilong He   +14 more
wiley   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

Andrology, Volume 14, Issue 6, Page 1579-1589, September 2026.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda, Jiřina Havránková, Hedvika Řimnáčová, Jiří Moravec, František Liška, Martin Knytl, Milena Králíčková, Jan Nevoral   +7 more
wiley   +1 more source

CDX2 in the formation of the trophectoderm lineage in primate embryos

Developmental Biology, 2009
The first lineage decision during mammalian development is the establishment of the trophectoderm (TE) and the inner cell mass (ICM). The caudal-type homeodomain protein Cdx2 is implicated in the formation and maintenance of the TE in the mouse. However, the role of CDX2 during early embryonic development in primates is unknown.
Sritanaudomchai, Hathaitip, Sparman, Michelle, Tachibana, Masahito, Clepper, Lisa, Woodward, Joy, Gokhale, Sumita, Wolf, Don, Hennebold, Jon, Hurlbut, William, Grompe, Markus, Mitalipov, Shoukhrat   +10 more
openaire   +2 more sources

Cell lineage specification and its regulation mechanisms during mammalian preimplantation development

浙江大学学报. 农业与生命科学版, 2018
Preimplantation development refers to the early embryonic development between fertilization and implantation. During this short developmental window (4.5 days of mouse), a series of morphological and developmental changes take place. In morphology, three
WANG Han, ZHAO Panpan, ZHANG Kun
doaj   +1 more source

Temporal Regulation of Ovine Interferon-tau Gene by the Transcription Factor Eomesodermin in the Peri-Implantation Period

Journal of Animal Reproduction and Biotechnology, 2019
Interferon tau (IFNT) regulation, an anti-luteolytic factor produced by conceptuses of the ruminant ungulates, is essential for the maintenance of early pregnancy, but a definitive mechanism for its temporal transcription has not been elucidated.
Min-Su Kim, Hyun-Joo Lim, Ji Hwan Lee, Tae Young Hur , Jun Kyu Son   +4 more
doaj   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, Volume 111, Issue 9, Page 4015-4040, 1 September 2026.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, Volume 600, Issue 16, Page 2226-2247, August 2026.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source