Results 61 to 70 of about 22,216 (269)
iNew Medicine, EarlyView.This illustration synthesizes the methods and conclusion of this study, demonstrating that the transfer of mosaic embryos following reimplantation genetic testing for aneuploidy does not increase the risk to postnatal health. ABSTRACT Next‐generation sequencing (NGS) has increased the detection of mosaic embryos during preimplantation genetic testing ...
Lili Chen +10 more
wiley +1 more source
eLife, 2017 The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-dependent Hippo signaling. However, the window of responsiveness to Hippo signaling, the exact timing of lineage commitment and the
Eszter Posfai +7 more
doaj +1 more source
Maternal and neonatal outcomes associated with trophectoderm biopsy
Fertility and Sterility, 2019 (Abstracted from Fertil Steril 2019;112:283–290) Despite a widespread increase in the use of preimplantation genetic testing (PGT), there remains inconclusive examination of maternal and neonatal outcomes after pregnancy achieved through in vitro fertilization (IVF) with PGT.
Wendy Y. Zhang +5 more
openaire +3 more sources
Ultrasound in Obstetrics &Gynecology, EarlyView.ABSTRACT Objectives To determine the prognostic value of serum β‐human chorionic gonadotropin (β‐hCG) for predicting live birth following single euploid frozen‐embryo transfer (FET), and to develop and validate a prognostic model (iHOPE) for this purpose. Methods This retrospective cohort study used data from two large fertility practices.
E. Kalafat +8 more
wiley +1 more source
Optimized protocol for naive human pluripotent stem cell-derived trophoblast induction
STAR Protocols, 2021 Summary: Human trophoblasts arise from the morula as trophectoderm, which differentiates into cytotrophoblast, syncytiotrophoblast, and extravillous trophoblast after implantation.
Shingo Io +2 more
doaj +1 more source
Distribution of endothelial cell protein C/activated protein C receptor (EPCR) during mouse embryo development. [PDF]
, 2002 The endothelial cell protein C receptor (EPCR) augments protein C activation by the thrombomodulin.thrombin complex. Deletion of the EPCR gene in mice has been reported to lead to embryonic lethality before embryonic day 10 (E10.0). To identify potential
Crawley, JT +3 more
core
Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids. [PDF]
, 2019 During gastrulation, the pluripotent epiblast self-organizes into the 3 germ layers-endoderm, mesoderm and ectoderm, which eventually form the entire embryo.
Chhabra, Sapna +4 more
core +1 more source
Sox2 Is Essential for Formation of Trophectoderm in the Preimplantation Embryo
PLoS ONE, 2010 In preimplantation mammalian development the transcription factor Sox2 (SRY-related HMG-box gene 2) forms a complex with Oct4 and functions in maintenance of self-renewal of the pluripotent inner cell mass (ICM). Previously it was shown that Sox2-/- embryos die soon after implantation.
Keramari, Maria +6 more
openaire +4 more sources
Andrology, EarlyView.ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda +7 more
wiley +1 more source
Single-cell transcriptomic characterization of sheep conceptus elongation and implantation
Cell Reports, 2023 Summary: Bidirectional communication between the developing conceptus and endometrium is essential for pregnancy recognition and establishment in ruminants.
Gong-Xue Jia +12 more
doaj +1 more source