Results 81 to 90 of about 22,216 (269)

A mRNA landscape of bovine embryos after standard and MAPK-inhibited culture conditions: a comparative analysis. [PDF]

, 2015
BACKGROUND: Genes and signalling pathways involved in pluripotency have been studied extensively in mouse and human pre-implantation embryos and embryonic stem (ES) cells.
A Graf, A Ralston, AC Eklund, AC Nicacio, AV Zimin, B Plusa, B Wilkinson, Bas Brinkhof, Bernard AJ Roelen, BPVL Telugu, C Chazaud, D Acampora, D Rizos, D Strumpf, D Xie, DA Stringfellow, DK Berg, DR Khan, EW Kuijk, F Izadyar, Frank M Riemers, GA Bó, GR Martin, H Auer, H Nagatomo, H Sumer, H Wu, Helena TA van Tol, Henk P Haagsman, J Nichols, J SantaLucia, J Schindelin, JA Hackett, JA Thomson, JA Thomson, JH Kim, JJ Parrish, JM Veltmaat, JS Kuo, K Imakawa, K Kondoh, K Kurimoto, Kaveh Mashayekhi, KM Johnson, KM Loh, L Brown, L Shi, LA Boyer, LS Lim, M Buehr, M Fürthauer, M Ozawa, M Roode, M Van Der Jeught, M Yamaji, M Zernicka-Goetz, M Zuker, MA Sirard, Marian JA Groot Koerkamp, MC Wallingford, MJ Evans, N Grabole, N Schrode, NB Ivanova, P Roepman, Q Li, Q Ying, QL Ying, R Edgar, R Jaenisch, RM Roberts, S Kurosaka, S Tanaka, S Wageningen van, Sascha G IJzer, SH Yang, SJ Roper, T Casci, T Ezashi, T Hamatani, T Margaritis, T Sakaguchi, T Sakurai, TS Tanaka, WA Kues, WN D’Souza, Y Chu, Y Grinblat, Y Wang, Y Yamanaka, YH Loh, YH Yang, Z Du, Z Ma, Z Madeja, Z Wang   +95 more
core   +2 more sources

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Tissue resolved, gene structure refined equine transcriptome. [PDF]

, 2017
BackgroundTranscriptome interpretation relies on a good-quality reference transcriptome for accurate quantification of gene expression as well as functional analysis of genetic variants.
Bellone, RR, Brown, CT, Finno, CJ, Mansour, TA, Mienaltowski, MJ, Murray, JD, Penedo, MC, Ross, PJ, Scott, EY, Valberg, SJ   +9 more
core   +1 more source

CDX2 in the formation of the trophectoderm lineage in primate embryos

Developmental Biology, 2009
The first lineage decision during mammalian development is the establishment of the trophectoderm (TE) and the inner cell mass (ICM). The caudal-type homeodomain protein Cdx2 is implicated in the formation and maintenance of the TE in the mouse. However, the role of CDX2 during early embryonic development in primates is unknown.
Sritanaudomchai, Hathaitip, Sparman, Michelle, Tachibana, Masahito, Clepper, Lisa, Woodward, Joy, Gokhale, Sumita, Wolf, Don, Hennebold, Jon, Hurlbut, William, Grompe, Markus, Mitalipov, Shoukhrat   +10 more
openaire   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, Volume 16, Issue 6, Page 1102-1114, June 2026.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Regulated mitochondrial DNA replication during oocyte maturation is essential for successful porcine embryonic development. [PDF]

, 2006
Cellular ATP is mainly generated through mitochondrial oxidative phosphorylation, which is dependent on mitochondrial DNA (mtDNA). We have previously demonstrated the importance of oocyte mtDNA for porcine and human fertilization.
Alexander, Jan, Altieri, Andrea, Barregård, Lars, Bignami, Margherita, Brüschweiler, Beat, Ceccatelli, Sandra, Cottrill, Bruce, Dall'Asta, Chiara, Dinovi, Michael, Edler, Lutz, EFSA Panel on Contaminants in the Food Chain (CONTAM), Eriksen, Gunnar Sundstøl, Grasl-Kraupp, Bettina, Hogstrand, Christer, Hoogenboom, Laurentius (Ron), Knutsen, Helle Katrine, Nebbia, Carlo Stefano, Oswald, Isabelle P., Petersen, Annette, Roldán-Torres, Ruth, Rose, Martin, Roudot, Alain-Claude, Schwerdtle, Tanja, Taranu, Ionelia, Vleminckx, Christiane, Vollmer, Günter, Wallace, Heather   +26 more
core   +6 more sources

Exposure to Gestational Intermittent Hypoxia Does Not Impair the Metabolic Function or Accelerate the Biological Ageing Process of Offspring of Either Sex

Journal of Sleep Research, Volume 35, Issue 3, June 2026.
ABSTRACT Obstructive sleep apnea (OSA), marked by intermittent hypoxia, is associated with obesity, type 2 diabetes and metabolic associated fatty liver disease. In pregnancy, it remains underdiagnosed despite links to gestational diabetes, hypertension, and foetal growth restriction.
Esther Valverde‐Perez, Margarida B. Almeida, Joana F. Sacramento, Elena Olea, Jesus Prieto‐Lloret, Asuncion Rocher, Silvia V. Conde   +6 more
wiley   +1 more source

Cell lineage specification and its regulation mechanisms during mammalian preimplantation development

浙江大学学报. 农业与生命科学版, 2018
Preimplantation development refers to the early embryonic development between fertilization and implantation. During this short developmental window (4.5 days of mouse), a series of morphological and developmental changes take place. In morphology, three
WANG Han, ZHAO Panpan, ZHANG Kun
doaj   +1 more source

Handmade Biopsy for Genotyping of In Vitro‐Produced Bovine Embryos

Anatomia, Histologia, Embryologia, Volume 55, Issue 3, May 2026.
ABSTRACT Blastocyst biopsy allows genomic selection of pre‐implantation bovine embryos, reducing generation interval and enhancing the genetic gain. We aimed to evaluate the suitability of a simple biopsy procedure, performed by hands, using a splitting microblade and a stereoscope, on in vitro‐produced embryos. Crossbred Bos taurus x B.
Luiz Sergio Almeida Camargo, Carolina Capobiango Romano Quintão, Julia Medeiros Cruz Lima de Martins, Marcos Vinicius Gualberto Barbosa Silva, Agostinho Jorge Reis dos Camargo, Celio Freitas, Daniele Ribeiro Lima de Reis, Marco Antonio Machado, Clara Slade Oliveira   +8 more
wiley   +1 more source

Temporal Regulation of Ovine Interferon-tau Gene by the Transcription Factor Eomesodermin in the Peri-Implantation Period

Journal of Animal Reproduction and Biotechnology, 2019
Interferon tau (IFNT) regulation, an anti-luteolytic factor produced by conceptuses of the ruminant ungulates, is essential for the maintenance of early pregnancy, but a definitive mechanism for its temporal transcription has not been elucidated.
Min-Su Kim, Hyun-Joo Lim, Ji Hwan Lee, Tae Young Hur , Jun Kyu Son   +4 more
doaj   +1 more source