Results 61 to 70 of about 21,086 (158)

TFAP2C is a key regulator of intrauterine trophoblast cell invasion and deep hemochorial placentation

JCI Insight
Transcription factor AP-2 gamma (TFAP2C) has been identified as a key regulator of the trophoblast cell lineage and hemochorial placentation. The rat possesses deep placentation characterized by extensive intrauterine trophoblast cell invasion, which ...
Esteban M. Dominguez, Ayelen Moreno-Irusta, Regan L. Scott, Khursheed Iqbal, Michael J. Soares   +4 more
doaj   +1 more source

KRT6A Is a Biomarker of PAS Progression and Enhances the Invasive Ability of Trophoblast Cells

Cells
Placenta Accreta Spectrum (PAS) is a severe obstetric disorder characterized by excessive trophoblast invasion into the uterine myometrium, leading to life-threatening hemorrhage at delivery.
Zhirong Guo, Jiaqi Huang, Weiran Zheng, Ruochong Dou, Xinrui Yang, Huixia Yang, Jingmei Ma   +6 more
doaj   +1 more source

Mechanism of microRNA‐152 Regulating Decidual Natural Killer Cell Viability and Affecting Trophoblast Cell Invasiveness via the HLA‐G/KIR2DL4 Axis

Kaohsiung Journal of Medical Sciences
Trophoblast cells are specialized placental epithelial cells essential for pregnancy maintenance. miR‐152 is implicated in trophoblast cell regulation and pregnancy failure.
Yang Yang, Sai Liu, Xiao‐Ming Zhu, You‐Yi Chen, Jing Zhao, Yu‐Fei Yuan, Yuan Ma   +6 more
doaj   +1 more source

KLF4 regulates trophoblast function and associates with unexplained recurrent spontaneous abortion

Journal of Translational Medicine
Background Recurrent spontaneous abortion (RSA) is defined as two or more consecutive spontaneous abortions before 20 weeks with the same spouse [1].
Yiling Tan, Jiayu Wang, Chunming Liu, Shujuan Wu, Mengqi Zhou, Yan Zhang, Tailang Yin, Jing Yang   +7 more
doaj   +1 more source

RETRACTED ARTICLE: Antiphospholipid antibodies inhibit the migration and invasion of trophoblast cells by suppressing the JNK/C-Jun/MMP1 signaling pathway

Journal of Translational Medicine
Background Antiphospholipid syndrome (APS) is an autoimmune disease primarily manifested by recurrent thrombosis and pregnancy-related complications.
Qingchen Wang, Weimin Feng, Yuan Tan, Jiao Qiao, Hongchao Liu, Qi Liu, He Wang, Qian Zhang, Jingjin Tao, Zhongxin Li, Boxin Yang, Zhen Xu, Chong Wang, Shuo Yang, Liyan Cui   +14 more
doaj   +1 more source

Hyperglycosylated-hCG: Its Role in Trophoblast Invasion and Intrauterine Growth Restriction. [PDF]

Cells, 2023
Herghelegiu CG, Veduta A, Stefan MF, Magda SL, Ionascu I, Radoi VE, Oprescu DN, Calin AM.   +7 more
europepmc   +1 more source

IFITM1 inhibits trophoblast invasion and is induced in placentas associated with IFN-mediated pregnancy diseases. [PDF]

iScience, 2023
Degrelle SA, Buchrieser J, Dupressoir A, Porrot F, Loeuillet L, Schwartz O, Fournier T.   +6 more
europepmc   +1 more source

GDF15 deficiency hinders human trophoblast invasion to mediate pregnancy loss through downregulating Smad1/5 phosphorylation. [PDF]

iScience, 2023
Zeng YT, Liu WF, Zheng PS, Li S.
europepmc   +1 more source

Extravillous trophoblast invasion and decidualization in cesarean scar pregnancies. [PDF]

Acta Obstet Gynecol Scand, 2022
Gao L, Chen H, Liu J, Wang M, Lin F, Yang G, Lash GE, Li P.   +7 more
europepmc   +1 more source

H3K27me3-modulated Hofbauer cell BMP2 signalling enhancement compensates for shallow trophoblast invasion in preeclampsia. [PDF]

EBioMedicine, 2023
Deng J, Zhao HJ, Zhong Y, Hu C, Meng J, Wang C, Lan X, Wang X, Chen ZJ, Yan J, Wang W, Li Y.   +11 more
europepmc   +1 more source