Results 101 to 110 of about 40,342 (338)

The impact and management of hyperemesis gravidarum: Current and future perspectives

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy affecting around 1%–3% of pregnancies worldwide and is the most common reason for hospital admission in early pregnancy. HG can have lasting consequences for both pregnant individuals and their offspring.
L. M. van der Minnen, I. J. Grooten, C. Dean, J. Trovik, R. C. Painter   +4 more
wiley   +1 more source

Use of the Abbott i‐STAT®1 point of care device for hCG quantification in early pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives To evaluate the use of the Abbott i‐STAT®1 point‐of‐care‐test (POCT) device for measurement of human chorionic gonadotropin (hCG) to support the management of early pregnancy complications in a remote early pregnancy unit (EPU). Methods Women attending the EPU who required an hCG blood test were invited to take part in the study ...
Caroline Joyce, Paula M. O'Shea, Rebecca Lynch, Seán J. Costelloe, Tommie V. McCarthy, John Coulter, Deirdre Hayes‐Ryan, Keelin O'Donoghue   +7 more
wiley   +1 more source

The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat [PDF]

, 2016
Women with chronic hypertension are at increased risk of maternal and fetal morbidity and mortality. We have previously characterized the stroke-prone spontaneously hypertensive rat (SHRSP) as a model of deficient uterine artery function and adverse ...
Beattie, Elisabeth, Delles, Christian, Graham, Delyth, Guzik, Tomasz, Morgan, Hannah, Nosalski, Ryszard, Small, Heather Yvonne   +6 more
core   +1 more source

A Preliminary Association Study of H19 Non‐Coding Gene Variants With Risk of Non‐Hodgkin Lymphoma: A Case–Control Study and Computational Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
Non‐Hodgkin lymphoma (NHL) is a kind of frequently occurring malignant tumor of the lymphoid hematopoietic system in the world. NHL comprises a large group of diverse lymphoid malignancies involving either the lymph nodes or extra nodal sites. It is more prevalent in males living in more developed countries over the age of 60 years.
Sara Kashani, Hoseinali Sasan, Behrouz Mollashahi, Gholamreza Bahari, Seyed Mahdi Hashemi, Mohsen Taheri   +5 more
wiley   +1 more source

Macrophage and Preeclampsia: Macrophage Polarization Imbalance at the Maternal‐Fetal Interface

Journal of Clinical Laboratory Analysis, EarlyView.
The development and progression of preeclampsia (PE) are associated with immune‐inflammatory responses induced by placental dysfunction. The polarization imbalance of decidual macrophages, particularly the increase in M1 polarization, exacerbates placental inflammation.
Yao Wei, Yang Su, Cheng Liu, Xiaolong Ma, Zihui Ling, Yilin Wang, Rui Qiao   +6 more
wiley   +1 more source

Is intermediate risk really intermediate? Comparison of karyotype and non‐invasive prenatal testing results of pregnancies at intermediate risk of trisomy 21 on maternal serum screening

Journal of Genetic Counseling, Volume 34, Issue 2, April 2025.
Abstract The purpose of this study was to assess the additional contribution of karyotyping compared with genome‐wide non‐invasive prenatal testing (NIPT) for pregnancies at intermediate risk for trisomy 21 (T21), calculated using the maternal serum screening without major structural anomalies detected through sonography.
Gul Alkan Bulbul, Emine Kirtis, Hulya Kandemir, Cem Yasar Sanhal, Sezin Yakut Uzuner, Sibel Berker Karauzum, Ibrahim Inanc Mendilcioglu   +6 more
wiley   +1 more source

β3‐Adrenoceptor Agonism to Mimic the Biological Effects of Intrauterine Hypoxia: Taking Great Strides Toward a Pharmacological Artificial Placenta

Medicinal Research Reviews, Volume 45, Issue 3, Page 842-866, May 2025.
ABSTRACT At different stages of life, from embryonic to postnatal, varying oxygen concentrations modulate cellular gene expression by enhancing or repressing hypoxia‐inducible transcription factors. During embryonic/fetal life, these genes encode proteins involved in adapting to a low‐oxygen environment, including the induction of specific enzymes ...
Luca Filippi, Francesca Innocenti, Francesca Pascarella, Rosa Teresa Scaramuzzo, Riccardo Morganti, Paola Bagnoli, Maurizio Cammalleri, Massimo Dal Monte, Maura Calvani, Alessandro Pini   +9 more
wiley   +1 more source

The role of DNA methylation in human trophoblast differentiation

Epigenetics, 2018
The placenta is a vital fetal exchange organ connecting mother and baby. Specialised placental epithelial cells, called trophoblasts, are essential for adequate placental function.
Teena K. J. B. Gamage, William Schierding, Daniel Hurley, Peter Tsai, Jackie L. Ludgate, Chandrakanth Bhoothpur, Lawrence W. Chamley, Robert J. Weeks, Erin C. Macaulay, Joanna L. James   +9 more
doaj   +1 more source

Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface [PDF]

, 2009
Plasma concentrations of biologically active vitamin D (1,25- (OH)2D) are tightly controlled via feedback regulation of renal 1-hydroxylase (CYP27B1; positive) and 24-hydroxylase (CYP24A1; catabolic) enzymes.
Albertson, Anderson, Arai, Avila, Barrera, Barrera, Bock, Bodnar, Boris Novakovic, Carter, Chaddha, Chiu, Chung, Coan, d'Alesio, Danielle Evain-Brion, Davis, Deeb, DeLuca, Delvin, Delvin, Diaz, Dimitriadis, Dodds, Du, Dusso, Eva Dimitriadis, Evans, Evans, Fischer, Friso, Holick, Hong Kiat Ng, Jeffrey M. Craig, Jennings, Kim, Kohler, Kovacs, Kumar, Lauridsen, Leader, Lechner, Li, Liu, Lohnes, Lopez, Lopez, Makin, Malloy, Mandy Sibson, Masuda, Muller, Murayama, Nelen, Nelen, Nelen, Novakovic, Ohyama, Pattillo, Pattillo, Paulson, Pavan, Peehl, Pendas-Franco, Pospechova, Rahnama, Rakyan, Richard Saffery, Ron, Ross, Ross, Ruth Morley, Salle, Seely, Serman, Shih Ie, Sikora, Siu-Caldera, Soundararajan, Stephan Beck, Stephanou, Sung, Tapia, Tashiro, Taylor, Thierry Fournier, Thomas Down, Tsang, Ursula Manuelpillai, Valdivielso, van der Molen, Vardhman Rakyan, Vigano, von Rango, Whitfield, Wietrzyk, Wong, Wong, Xie, Zehnder, Zhang, Zhou   +101 more
core   +3 more sources

S‐Methyl Methanethiosulfonate, the Main Human Metabolite of S‐Methyl‐L‐Cysteine Sulfoxide, Alters Energy Metabolism in Prostate Cancer Cells

Molecular Nutrition &Food Research, Volume 69, Issue 8, April 2025.
In this study, we show that the sulfur compound commonly found in cruciferous and allium vegetables and the main human metabolite of S‐methyl‐L‐cysteine sulfoxide, called S‐methyl methanethiosulfonate (MMTSO), alters energy metabolism in DU145 prostate cancer cells.
Gemma Beasy, Federico Bernuzzi, Priscilla Day‐Walsh, Perla Tronsco‐Rey, Marianne Defernez, Shikha Saha, Richard F. Mithen, Maria H. Traka, Paul A. Kroon   +8 more
wiley   +1 more source