Results 121 to 130 of about 21,207 (299)

Susceptibility of cultured human trophoblasts to infection with human immunodeficiency virus type 1

, 1991
Primary cultures of essentially pure human term trophoblasts were studied to determine their ability to support the expression of complete proviral clones of human immunodeficiency virus (HIV) and their permissiveness to this virus.
Juhl, C., Spire, B., Zachar, V.; id_orcid, Norskov-Lauritsen, N., Chermann, J. C., Ebbesen, P.   +5 more
core   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

IL-10 reduces levels of apoptosis in Toxoplasma gondii-infected trophoblasts.

, 2013
BACKGROUND: To analyze the effects of IL-10 on the HLA-G expression and the apoptosis of trophoblasts infected with Toxoplasma gondii. METHODS: T. gondii-infected or uninfected human trophoblasts and immortalized human placental BeWo cells were cultured ...
Xuemei Hu, Mingdong Zhao, Haixia Zhang, Xiaoyu Zhai, Yang Liu, Ruijin Zhang, Xiaoyan Xu   +6 more
core   +1 more source

Immunophenotypic assessment of pure embryonal carcinoma and yolk sac tumour suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche

Histopathology, EarlyView.
Immunohistochemical analysis of transcription factors in GCNIS associated with pure EC and YST suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche. In these tumors, reprogramming may occur immediately upon invasion of the stroma or within seminiferous tubules but outside the spermatogonial niche (i.e., in intratubular ...
Daisy Maharjan, Květoslava Michalová, Joao Lobo, Jennifer Gordetsky, Fiona MacLean, Ankur R Sangoi, Daniel Berney, Chia‐Sui Kao, Costantino Ricci, Adeboye O Osunkoya, Maria Rosaria Raspollini, Geert JLH van Leenders, Muhammad T Idrees, Lee Ann Baldridge, Thomas M Ulbright, Andres M Acosta   +15 more
wiley   +1 more source

Effect of formaldehyde exposure on oxidative status in human trophoblasts.

, 2015
(A) The mRNA expression of OXSR1, catalase, GPx-3, GSR, SOD1 and SOD2 in trophoblasts with or without (control) formaldehyde exposure for 24 h. The mRNA data are expressed as the level of each mRNA marker normalized by actin beta mRNA expression (ACTB). (
Guillaume Pidoux (771871), Fatima Ferreira (163114), Patrice Thérond (372067), Christelle Simasotchi (771872), Pascale Gerbaud (86939), Jean Guibourdenche (297022), Danièle Evain-Brion (86941), Sophie Gil (771873)   +7 more
core   +1 more source

Marked attenuation of P63 expression in plasmacytoid urothelial carcinoma with expanded immunohistochemical framework including E‐cadherin, P120, HER2 and TRPS1

Histopathology, EarlyView.
Plasmacytoid urothelial carcinoma demonstrates marked attenuation of p63 expression together with frequent disruption of the E‐cadherin–p120 adhesion complex, supporting its characteristic discohesive growth pattern. Standardized HER2 scoring identifies a substantial positive subset, highlighting diagnostic pitfalls and potential therapeutic relevance ...
Busra Yaprak Bayrak, Kemal Kosemehmetoglu, Busra Ozbek, Sercan Simsek, Murat Oktay, Ganime Coban, Dilara Irem Arslan Kahraman, Egemen Akıncıoglu, Melek Buyukgok, Selin Colak, Hatice Nese Dogan, Burak Gurel, Selva Kabul, Kerem Karaca, Elif Ozsagir, Ece Ozturk, Havva Serap Toru, Gupse Turan, Nazif Alperen Yıldırım, Ozlem Nur Yıldız, Yasemin Yuyucu Karabulut, Liang Cheng, Mahmut Akgul   +22 more
wiley   +1 more source

Guidance for Specialised Cancer Nursing of People With Gynaecological Cancers: A Scoping Review

Journal of Clinical Nursing, EarlyView.
ABSTRACT Background Gynaecological cancer nurses are crucial to the delivery of quality, specialised care to meet the needs of people with these cancers. The extent of evidence‐based guidance to support nursing care is unknown. Aim To identify and describe existing international guidance for specialised gynaecological cancer nursing care.
Natalie Williams, Georgia Halkett, Tracey Moroney, Sharon MacLean, Olivia Cook   +4 more
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

The role of side-population trophoblasts in normal and abnormal placentation

, 2019
The human placenta is a fetal organ that is vital for healthy growth of the baby. Adequate placentation requires the normal function of specialised epithelial cells called trophoblasts, of which there are three main populations: cytotrophoblasts ...
Gamage, Teena
core  

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source