ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley +8 more
wiley +1 more source
HIF2α-induced lysyl oxidase safeguards successful pregnancy by remodelling collagens at the feto-maternal interface. [PDF]
Aikawa S +13 more
europepmc +1 more source
Guidance for Specialised Cancer Nursing of People With Gynaecological Cancers: A Scoping Review
ABSTRACT Background Gynaecological cancer nurses are crucial to the delivery of quality, specialised care to meet the needs of people with these cancers. The extent of evidence‐based guidance to support nursing care is unknown. Aim To identify and describe existing international guidance for specialised gynaecological cancer nursing care.
Natalie Williams +4 more
wiley +1 more source
Recent insights into the immunobiology of congenital cytomegalovirus infection. [PDF]
Enninga EAL, Schleiss MR, Bierle CJ.
europepmc +1 more source
Actinomycin Derivatives: Structural Diversification and Biological Activities
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley +1 more source
Semaglutide Induces Oxidative Stress and Differentially Modulates mTOR-Dependent Growth and Invasion in Human Trophoblast Cell Models: Implications for Placental Function. [PDF]
Thurmond E +7 more
europepmc +1 more source
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon +5 more
wiley +1 more source
SIRT1-NCOR2 Corepressor Modulates Trophoblast-Macrophage Interactions in Preeclampsia. [PDF]
Liu Z +8 more
europepmc +1 more source
Placental ischemia in pre‐eclampsia initiates cytokine‐driven endothelial dysfunction, angiogenic imbalance, oxidative stress, and thromboinflammation. Elevated TNF‐α, IL‐6, IL‐17, sFlt‐1, and complement activation promote vasoconstriction, thrombosis, and cardiovascular instability.
Emmanuel Ifeanyi Obeagu
wiley +1 more source
SUMOylation Inhibitor TAK-981 Alleviates Hallmark Features of Preeclampsia Related to High Glucocorticoid Exposure by Inhibiting Placental Oxidative Stress in Rats. [PDF]
Xiao S +6 more
europepmc +1 more source

