Results 21 to 30 of about 40,342 (338)

Uterine spiral artery remodeling involves endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions. [PDF]

open access: yes, 2005
Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers.
Ashton, SV   +6 more
core   +1 more source

The Immunology of Syncytialized Trophoblast [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Multinucleate syncytialized trophoblast is found in three forms in the human placenta. In the earliest stages of pregnancy, it is seen at the invasive leading edge of the implanting embryo and has been called primitive trophoblast. In later pregnancy, it is represented by the immense, multinucleated layer covering the surface of placental villi and by ...
Danny J. Schust   +6 more
openaire   +3 more sources

Chorion laeve trophoblasts of preeclamptic fetal membranes: histochemically detectable enzyme activities do not change at a subcellular level

open access: yesEuropean Journal of Histochemistry, 2009
We examined the subcellular localization of ADPdegrading activity and cytochrome c oxidase (CCO) activity in chorion laeve trophoblasts from term and near term human fetal membranes, and compared them with those from severe preeclamptic fetal membranes ...
S Matsubara   +5 more
doaj   +1 more source

Investigation into the Role of Forkhead Box A1 (FOXA1) in Late-Onset Preeclampsia of a Prospective Cohort Study and Its Actions on Trophoblast Invasion and Migration

open access: yesClinical and Experimental Obstetrics & Gynecology, 2023
Background: The primary objective was to investigate how Forkhead Box A1 (FOXA1) contributes to late-onset preeclampsia (LOPE) and its impact on trophoblast invasion and migration.
Juan Zhu   +8 more
doaj   +1 more source

Transcriptional factor PU.1 regulates decidual C1q expression in early pregnancy in human [PDF]

open access: yes, 2015
"Copyright: © 2015 Madhukaran, Kishore, Jamil, Teo, Choolani and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Choolani, M   +5 more
core   +2 more sources

Interferon gamma is involved in apoptosis of trophoblast cells at the maternal–fetal interface following Toxoplasma gondii infection

open access: yesInternational Journal of Infectious Diseases, 2015
Objective: To assess whether interferon gamma (IFN-γ) secreted by decidual natural killer (dNK) cells at the maternal–fetal interface is involved in the apoptosis of trophoblast cells (trophoblasts) following Toxoplasma gondii infection.
Ling Zhang   +8 more
doaj   +1 more source

Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP. [PDF]

open access: yes, 2019
Subversion of endoplasmic reticulum (ER) function is a feature shared by multiple intracellular bacteria and viruses, and in many cases this disruption of cellular function activates pathways of the unfolded protein response (UPR).
Atluri, Vidya L   +14 more
core   +1 more source

Functional Analysis of p21Cip1/CDKN1A and Its Family Members in Trophoblastic Cells of the Placenta and Its Roles in Preeclampsia

open access: yesCells, 2021
Preeclampsia (PE), a gestational hypertensive disease originating from the placenta, is characterized by an imbalance of various cellular processes.
Nina-Naomi Kreis   +7 more
doaj   +1 more source

Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy. [PDF]

open access: yes, 2010
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Brosnihan, KB   +12 more
core   +1 more source

From Coxiella burnetii Infection to Pregnancy Complications: Key Role of the Immune Response of Placental Cells

open access: yesPathogens, 2021
The infection of pregnant animals and women by Coxiella burnetii, an intracellular bacterium, compromises both maternal health and foetal development. The placenta is targeted by C.
Sandra Madariaga Zarza   +2 more
doaj   +1 more source

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