Results 11 to 20 of about 7,144 (202)
Tropoelastin and Elastin Assembly [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience, and cell interactivity to a broad range of elastic tissues.
Jazmin Ozsvar +9 more
doaj +4 more sources
Dill Extract Induces Elastic Fiber Neosynthesis and Functional Improvement in the Ascending Aorta of Aged Mice with Reversal of Age-Dependent Cardiac Hypertrophy and Involvement of Lysyl Oxidase-Like-1 [PDF]
Biomolecules, 2020 Elastic fibers (90% elastin, 10% fibrillin-rich microfibrils) are synthesized only in early life and adolescence mainly by the vascular smooth muscle cells through the cross-linking of its soluble precursor, tropoelastin.
Wassim Fhayli +7 more
doaj +4 more sources
Small StructuresElastin‐like polypeptides (ELPs), genetically programmable biomaterials derived from natural tropoelastin, exhibit unique reversible self‐assembly and aggregation behaviors driven by sequence‐encoded phase transitions.
Yang Yuan +9 more
doaj +2 more sources
Biomolecular Changes Upon Ablative Laser Therapy of the Skin: A Scoping Review. [PDF]
Int J Dermatol(Fractional) ablative laser therapy results in a wound healing response characterized by an inflammatory phase, dermal matrix degradation, and remodeling, collagenesis and elastogenesis. This is characterized by an increase in metalloproteinases, collagen type I, III, VII, and tropoelastin.
Debeuf MPH +4 more
europepmc +2 more sources
Circulation: Cardiovascular Imaging, 2018 Background: Elastolysis and ineffective elastogenesis favor the accumulation of tropoelastin, rather than cross-linked elastin, in atherosclerotic plaques. We developed gadolinium-labeled tropoelastin-specific magnetic resonance contrast agents for tropoelastin imaging in animal models. Methods
Phinikaridou, Alkystis +6 more
+10 more sources
Biochemistry of tropoelastin [PDF]
European Journal of Biochemistry, 1998 Elastic fibres are an important component of the extracellular matrix and are made of two major components : the more abundant cross‐linked elastic protein elastin and the multi‐component microfibrils. The biosynthesis of elastic fibres is a complex process involving the interplay of many diverse proteins and genes with elastin as the major component ...
B, Vrhovski, A S, Weiss
openaire +2 more sources
Radioimmunological identification of tropoelastin [PDF]
Biochemical Journal, 1976 Antiserum was prepared in sheep against insoluble elastin isolated from embryonic-chick aortae. In an indirect immunoprecipitation test, the antiserum reacted quantitatively with small amounts of radioactively labelled purified tropoelastin prepared from embryonic-chick aortae. The antiserum did not cross-react with chick procollagen, and the antiserum
P, Christner +3 more
openaire +2 more sources
Molecular Therapy: Nucleic Acids, 2023 Loss of elastin due to aging, disease, or injury can lead to impaired tissue function. In this study, de novo tropoelastin (TE) synthesis is investigated in vitro and in vivo using different TE-encoding synthetic mRNA variants after codon optimization ...
Sonia Golombek +14 more
doaj +1 more source
Archives of Medical Science, 2020 Introduction Androgenetic alopecia (AGA) or male pattern baldness is a polygenic disease with a high prevalence in the Caucasian population, with psychosocial implications. However, the molecular mechanisms involved are unknown. The aim of this study was
Miguel A. Ortega +7 more
doaj +1 more source
Frontiers in Genetics, 2021 Latent TGFβ binding protein-4 (LTBP4) is a multi-domain glycoprotein, essential for regulating the extracellular bioavailability of TGFβ and assembly of elastic fibre proteins, fibrillin-1 and tropoelastin.
Yasmene F. Alanazi +7 more
doaj +1 more source