Results 81 to 90 of about 2,192 (170)
, 2002 To test the hypothesis that early interventional treatment with insulin-like growth factor-1 (IGF-1) alleviates subsequent development of dilated cardiomyopathy, cardiac-specific IGF-1 expression was introduced by selective cross-breeding into a ...
Sandra Witt +11 more
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Tropomodulin caps the pointed ends of actin filaments. [PDF]
The Journal of cell biology, 1994 Many proteins have been shown to cap the fast growing (barbed) ends of actin filaments, but none have been shown to block elongation and depolymerization at the slow growing (pointed) filament ends. Tropomodulin is a tropomyosin-binding protein originally isolated from red blood cells that has been localized by immunofluorescence staining to a site at ...
A, Weber +3 more
openaire +2 more sources
European Journal of Heart Failure, Volume 27, Issue 11, Page 2313-2324, November 2025.The analysis workflow, findings and potential clinical consequences of iron deficiency in heart failure (HF). From 881 patients with worsening HF, whole blood transcriptome was analysed using the Affymetrix Human Transcriptome Array (HTA) 2.0. Subjects were stratified according to their transferrin saturation (TSAT) levels as iron‐deficient (TSAT <20%)
Niels Grote Beverborg +17 more
wiley +1 more source
, 2004 Recently, important differences between myofibrillogenesis in cultured cardiomyocytes vs. the three-dimensional setting in situ could be determined. We investigated thin filament assembly in situ by confocal microscopy of whole-mount preparations of ...
Ehler, E, Perriard, J C, Fowler, V M
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MOLECULAR MECHANISMS OF ISOFORM-DEPENDENT INTERACTIONS OF PROTEINS FROM THE TROPOMODULIN FAMILY WITH THEIR BINDING PARTNERS [PDF]
, 2016 Actin filaments are major components of the cytoskeleton in eukaryotic cells and are involved in vital cellular functions such as cell motility and muscle contraction.
Colpan, Mert
core +4 more sources
Super‐Resolution Microscopy in Tissue Engineering
Advanced Materials Interfaces, Volume 12, Issue 19, October 6, 2025.Super‐resolution microscopy (SRM) has advanced tissue engineering by providing nanoscale insights into cellular interactions. It reveals detailed cell membrane structures, tracks vesicle and virus entry, and visualizes the cytoskeleton. SRM also improves understanding of cell migration, facilitating tissue regeneration, vascularization, immune ...
Navid Rabiee +2 more
wiley +1 more source
Tropomodulin Protects α-Catenin-Dependent Junctional-Actin Networks under Stress during Epithelial Morphogenesis [PDF]
, 2012 Summaryα-catenin is central to recruitment of actin networks to the cadherin-catenin complex [1, 2], but how such networks are subsequently stabilized against stress applied during morphogenesis is poorly understood.
Lynch, Allison M. +7 more
core +1 more source
, 2010 The short actin filaments in the red blood cell (RBC) membrane skeleton are capped at their pointed ends by tropomodulin 1 (Tmod1) and coated with tropomyosin (TM) along their length.
Kuypers, F A +15 more
core +2 more sources
Advanced Science, Volume 12, Issue 37, October 6, 2025.Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang +6 more
wiley +1 more source
, 2009 . Tropomodulin 1 (TMOD1) is a member of the tropomodulin family, which are highly conserved capping proteins of the pointed ends of the erythrocyte membrane and sarcomeric actin filaments.
S. Zhao +6 more
core +1 more source