Tropomyosin receptor kinase (TRK) biology and the role of NTRK gene fusions in cancer
Annals of Oncology, 2019 The tropomyosin receptor kinase (TRK) family of receptor tyrosine kinases are encoded by NTRK genes and have a role in the development and normal functioning of the nervous system. Since the discovery of an oncogenic NTRK gene fusion in colorectal cancer
A. Amatu +5 more
semanticscholar +1 more source
Actin, α-actinin, and tropomyosin interaction in the structural organization of actin filaments in nonmuscle cells [PDF]
, 1975 During the spreading of a population of rat embryo cells, approximately 40% of the cells develop a strikingly regular network which precedes the formation of the straight actin filament bundles seen in the fully spread out cells.
Lazarides, Elias
core +1 more source
The isolation of differentially expressed cDNA clones from the filarial nematode Brugia pahangi [PDF]
, 1999 A cDNA library constructed from 3 day post-infective L3 of the filarial nematode Brugia pahangi was screened by differential hybridization with cDNA probes prepared from different life-cycle stages.
Devaney, E. +4 more
core +1 more source
Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta [PDF]
, 2010 IgA and IgE activity against Teladorsagia circumcincta was investigated in a flock of Texel lambs following natural, mixed nematode infection among lambs.
Bishop, S.C. +6 more
core +1 more source
Specific fluorescent labeling of chicken myofibril Z-line proteins catalyzed by guinea pig liver transglutaminase [PDF]
, 1979 Guinea pig liver transglutaminase has been found to catalyze the covalent incorporation of dansylcadaverine into chicken skeletal muscle myofibril proteins.
Gard, David L., Lazarides, Elias
core +1 more source
Actin–tropomyosin distribution in non-muscle cells
Journal of Muscle Research and Cell Motility, 2019 The interactions of cytoskeletal actin filaments with myosin family motors are essential for the integrity and function of eukaryotic cells. They support a wide range of force-dependent functions.
D. Manstein +3 more
semanticscholar +1 more source
Thin filament dysfunctions caused by mutations in tropomyosin Tpm3.12 and Tpm1.1
Journal of Muscle Research and Cell Motility, 2019 Tropomyosin is the major regulator of the thin filament. In striated muscle its function is to bind troponin complex and control the access of myosin heads to actin in a Ca2+-dependent manner.
J. Moraczewska
semanticscholar +1 more source
Turkish Journal of Agriculture: Food Science and Technology, 2023 While shellfish species are widely consumed due to their nutritional advantages, they are also among the top eight food items for food-borne allergies.
Elif Tuğçe Aksun Tümerkan
doaj +1 more source
Distortion of the Actin A-Triad Results in Contractile Disinhibition and Cardiomyopathy
Cell Reports, 2017 Striated muscle contraction is regulated by the movement of tropomyosin over the thin filament surface, which blocks or exposes myosin binding sites on actin.
Meera C. Viswanathan +7 more
doaj +1 more source
Magnetic susceptibility anisotropy of myocardium imaged by cardiovascular magnetic resonance reflects the anisotropy of myocardial filament α-helix polypeptide bonds. [PDF]
, 2015 BackgroundA key component of evaluating myocardial tissue function is the assessment of myofiber organization and structure. Studies suggest that striated muscle fibers are magnetically anisotropic, which, if measurable in the heart, may provide a tool ...
Dibb, Russell, Liu, Chunlei, Qi, Yi
core +1 more source