Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. [PDF]
PLoS ONE, 2012 The contractile response of the heart can be altered by disease-related protein modifications to numerous contractile proteins. By utilizing an IAANS labeled fluorescent troponin C, [Formula: see text], we examined the effects of ten disease-related ...
Bin Liu +4 more
doaj +1 more source
Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study [PDF]
, 2018 Aims: To test the prognostic value of emerging biomarkers in the Reduction of Events by Darbepoetin Alfa in Heart Failure (RED-HF) trial. Methods and results: Circulating cardiac [N-terminal pro-B-type natriuretic peptide (NT-proBNP), and high ...
Alehagen +34 more
core +4 more sources
Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]
, 2014 Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core +2 more sources
Troponins, Acute Coronary Syndrome and Renal Disease: From Acute Kidney Injury Through End-stage Kidney Disease [PDF]
, 2019 The diagnosis of acute coronary syndromes (ACS) is heavily dependent on cardiac biomarker assays, particularly cardiac troponins. ACS, particularly non-ST segment elevation MI, are more common in patients with acute kidney injury, chronic kidney disease (
Banerjee, A, Banerjee, D, Ferrett, C
core +2 more sources
Which diagnostic tests are most useful in a chest pain unit protocol? [PDF]
, 2005 Background The chest pain unit (CPU) provides rapid diagnostic assessment for patients with acute, undifferentiated chest pain, using a combination of electrocardiographic (ECG) recording, biochemical markers and provocative cardiac testing.
Angelini, K. +4 more
core +3 more sources
PLoS ONE, 2021 BackgroundThe treatment of myopericarditis is different than that of acute myocardial infarction (AMI). However, since their clinical presentation is frequently similar it may be difficult to distinguish between these entities despite a disparate ...
Simcha R Meisel +13 more
doaj +1 more source
The 99th percentile of reference population for cTnI and cTnT assay: Methodology, pathophysiology and clinical implications [PDF]
, 2017 According to recent international guidelines, including the 2012 Third Universal Definiton of Myocardial Infarction by the Joint ESC/ACCF/AHA/WHF Task Force, an increase in cardiac troponin (cTn) levels over the 99th percentile upper reference limit ...
Clerico, Aldo +6 more
core +1 more source
The isolation of differentially expressed cDNA clones from the filarial nematode Brugia pahangi [PDF]
, 1999 A cDNA library constructed from 3 day post-infective L3 of the filarial nematode Brugia pahangi was screened by differential hybridization with cDNA probes prepared from different life-cycle stages.
Devaney, E. +4 more
core +1 more source
ST2 and Multimarker Testing in Acute Decompensated Heart Failure [PDF]
, 2015 Most data on heart failure biomarkers have been derived from patient cohorts with chronic disease. However, risk prediction in patients admitted with acute decompensated heart failure (ADHF) remains a challenge.
Antoni, Md +7 more
core +1 more source
Analysis of myofibrillar and sarcoplasmic proteins in pork meat by capillary gel electrophoresis
Foods and Raw Materials, 2018 Myofibrillar and sarcoplasmic proteins were extracted from pork meat (M. Longissimus dorsi) and then separated by capillary gel electrophoresis (CGE). Migration time and peak areas of individual protein molecules in the electropherogram were analysed ...
Radoslav Grujić, Danica Savanović
doaj +1 more source