Results 21 to 30 of about 19,950,370 (208)

Micro-mechanical response and power-law exponents from the longitudinal fluctuations of F-actin solutions [PDF]

Soft Matter, 2023,19, 3652-3660, 2022
We investigate the local fluctuations of filamentous actin (F-actin), with focus on the skeletal thin filament, using single-particle optical trapping interferometry. This experimental technique allows us to detect the Brownian motion of a tracer bead immersed in a complex fluid with nanometric resolution at the microsecond time-scale.
arxiv   +1 more source

Effect of helium pre- or postconditioning on signal transduction kinases in patients undergoing coronary artery bypass graft surgery [PDF]

, 2016
Background: The noble gas helium induces pre- and postconditioning in animals and humans. Volatile anesthetics induce cardioprotection in humans undergoing coronary artery bypass graft (CABG) surgery.
Brevoord, Daniel, De Hert, Stefan, de Mol, Bas A, Hollmann, Markus W, Kerindongo, Raphaela P, Preckel, Benedikt, Schlack, Wolfgang S, Smit, Kirsten F, van Dieren, Susan, Weber, Nina C   +9 more
core   +12 more sources

Tissue-specific interactions of TNI isoforms with other TN subunits and tropomyosins in C. elegans: The role of the C- and N-terminal extensions [PDF]

, 2007
The aim of this study is to investigate the function of the C-terminal extension of three troponin I isoforms, that are unique to the body wall muscles of Caenorhabditis elegans and to understand the molecular interactions within the TN complex between ...
al-Hillawi, Anyanful, Chong, Cummins, Farah, Fisher, Frederick Anokye-Danso, Gavin, Gordon, Grand, Grand, Hiroaki Kagawa, Hitchcock-DeGregori, Jha, Kagawa, Kagawa, Maira, Md. Ziaul Amin, Myers, Ohtsuki, Pearlstone, Perry, Perry, Razia Ruksana, Ruksana, Sheng, Syska, Takeda, Tanaka, Terami, Tetsuya Bando, Vassylyev, Walhout, Ward, Yasuji Sakube, Yasuo Takashima   +35 more
core   +1 more source

Cardiac troponin I as compared to troponin T for the detection of myocardial damage in horses [PDF]

, 2015
Background: Different cardiac troponin I (cTnI) assays give different results. Only 1 manufacturer has marketed troponin T (cTnT) assays. Therefore, cTnT often is preferred for detection of myocardial infarction in human patients.
De Clercq, Dominique, Decloedt, Annelies, Van Der Vekens, Nicky, van Loon, Gunther, Ven, Sofie   +4 more
core   +1 more source

Cardiac biomarkers by point-of-care testing - back to the future? [PDF]

, 2020
The measurement of the cardiac troponins (cTn), cardiac troponin T (cTnT) and cardiac troponin I (cTnI) are integral to the management of patients with suspected acute coronary syndromes (ACS).
Collinson, P
core   +1 more source

Prediction of cardiovascular disease risk by cardiac biomarkers in 2 United Kingdom cohort studies: does utility depend on risk thresholds for treatment? [PDF]

, 2016
We tested the predictive ability of cardiac biomarkers N-terminal pro B-type natriuretic peptide (NT-proBNP), high-sensitivity troponin T, and midregional pro adrenomedullin for cardiovascular disease (CVD) events using the British Regional Heart Study ...
Hart, Carole, McConnachie, Alex, Murray, Heather, Papacosta, Olia, Preiss, David, Ramsay, Sheena, Sattar, Naveed, Upton, Mark, Wannamethee, Goya, Watt, Graham, Welsh, Paul, Whincup, Peter   +11 more
core   +1 more source

Fluorescent probes of the orientation of myosin regulatory light chains in relaxed, rigor, and contracting muscle. [PDF]

, 1996
The orientation of the light-chain region of myosin heads in relaxed, rigor, and isometrically contracting fibers from rabbit psoas muscle was studied by fluorescence polarization. Cysteine 108 of chicken gizzard myosin regulatory light chain (cgRLC) was
Irving, M., Kendrick-Jones, J., Ling, Nicholas, Shrimpton, C., Sleep, J.   +4 more
core   +2 more sources

The Generic Isogeny Decomposition of the Prym Variety of a Cyclic Branched Covering [PDF]

Geometriae Dedicata (2022), 2021
Let $f\colon S'\longrightarrow S$ be a cyclic branched covering of smooth projective surfaces over $\mathbb{C}$ whose branch locus $\Delta\subset S$ is a smooth ample divisor. Pick a very ample complete linear system $|\mathcal{H}|$ on $S$, such that the polarized surface $(S, |\mathcal{H}|)$ is not a scroll nor has rational hyperplane sections.
arxiv   +1 more source

Structural and functional consequences of the cardiac troponin C L48Q Ca(2+)-sensitizing mutation.

Biochemistry, 2012
Calcium binding to the regulatory domain of cardiac troponin C (cNTnC) causes a conformational change that exposes a hydrophobic surface to which troponin I (cTnI) binds, prompting a series of protein-protein interactions that culminate in muscle ...
Dan D. Wang, I. M. Robertson, Monica X. Li, M. E. McCully, M. L. Crane, Z. Luo, A. Tu, V. Daggett, B. Sykes, M. Regnier   +9 more
semanticscholar   +1 more source

A Mutation in TNNC1-encoded Cardiac Troponin C, TNNC1-A31S, Predisposes to Hypertrophic Cardiomyopathy and Ventricular Fibrillation*

Journal of Biological Chemistry, 2012
Background: Cardiac troponin C mutations are rare causes of HCM. A novel mutation in TNNC1 gene was identified in a pediatric HCM patient. Results: Functional characterization demonstrated increased myofilament Ca2+ affinity.
Michelle S. Parvatiyar, A. P. Landstrom, Cícero Figueiredo-Freitas, J. Potter, M. Ackerman, J. Pinto   +5 more
semanticscholar   +1 more source