Results 71 to 80 of about 19,950,370 (208)

The phosphorylation sites of troponin T from white skeletal muscle and the effects of interaction with troponin C on their phosphorylation by phosphorylase kinase.

Biochemical Journal, 1977
1. The phosphorylation of troponin T from rabbit white sketetal muscle is catalysed by phosphorylase kinase, but not at a significant rate by bovine 3':5'-cyclic AMP-dependent protein kinase. 2.
A. Moir, H. Cole, S. Perry
semanticscholar   +1 more source

Anthracycline-Induced Cardiotoxicity: Cardiac Monitoring by Continuous Wave-Doppler Ultrasound Cardiac Output Monitoring and Correlation to Echocardiography [PDF]

, 2012
Background: Anthracyclines are agents with a well-known cardiotoxicity. The study sought to evaluate the hemodynamic response to an anthracycline using real-time continuous-wave (CW)-Doppler ultrasound cardiac output monitoring (USCOM) and ...
Andreas Hausmann, Cardinale D, Cardinale D, Cardinale D, Cardinale D, Cheitlin MD, Cheitlin MD, Cooper LT, Cooper LT, Dey I, Dorothee Baur, Elliott P, Goorin AM, Gustafsson F, Hans Joachim Stemmler, Iwanaga Y, Jain D, Johanna Tischer, Kinnunen P, Knobloch K, Knobloch K, Knobloch K, Koh E, Lipshultz SE, Meinardi MT, Mueller C, Mueller C, Mueller T, Patricia Suhl, Petra Stieber, Rademaker MT, Ryberg M, Sandra Geiger, Sophia Horster, Steinherz LJ, Stemmler HJ, Tan HL, Urek R, van Lelyveld-Haas LE, Veronika Lange   +39 more
core   +1 more source

A Functional and Structural Study of Troponin C Mutations Related to Hypertrophic Cardiomyopathy*

Journal of Biological Chemistry, 2009
Recently four new hypertrophic cardiomyopathy mutations in cardiac troponin C (cTnC) (A8V, C84Y, E134D, and D145E) were reported, and their effects on the Ca2+ sensitivity of force development were evaluated (Landstrom, A. P., Parvatiyar, M. S., Pinto, J.
J. Pinto, Michelle S. Parvatiyar, Michelle A. Jones, Jingsheng Liang, M. Ackerman, J. Potter   +5 more
semanticscholar   +1 more source

Mouse Models of Cardiomyopathies Caused by Mutations in Troponin C. [PDF]

Int J Mol Sci, 2023
Tikunova SB, Thuma J, Davis JP.
europepmc   +1 more source

Biosensors for cardiac biomarkers detection: a review [PDF]

, 2012
The cardiovascular disease (CVD) is considered as a major threat to global health. Therefore, there is a growing demand for a range of portable, rapid and low cost biosensing devices for the detection of CVD.
Gurbuz, Yasar, Gürbüz, Yaşar, Kolkar Mohammed, Javed Hussain Niazi, Qureshi, Anjum   +3 more
core   +1 more source

Solution Structure of Human Cardiac Troponin C in Complex with the Green Tea Polyphenol, (−)-Epigallocatechin 3-Gallate*

Journal of Biological Chemistry, 2009
Heart muscle contraction is regulated by Ca2+ binding to the thin filament protein troponin C. In cardiovascular disease, the myofilament response to Ca2+ is often altered.
I. M. Robertson, Monica X. Li, B. Sykes
semanticscholar   +1 more source

YTnC2, an improved genetically encoded green calcium indicator based on toadfish troponin C. [PDF]

FEBS Open Bio, 2023
Subach OM, Vlaskina AV, Agapova YK, Nikolaeva AY, Varizhuk AM, Podgorny OV, Piatkevich KD, Patrushev MV, Boyko KM, Subach FV.   +9 more
europepmc   +1 more source

Risk stratification in non-ST elevation acute coronary syndromes: risk scores, biomarkers and clinical judgment [PDF]

, 2015
Undifferentiated chest pain is one of the most common reasons for emergency department attendance and admission to hospitals. Non-ST elevation acute coronary syndrome (NSTE-ACS) is an important cause of chest pain, and accurate diagnosis and risk ...
Berry, Colin, Corcoran, David, Grant, Patrick   +2 more
core   +2 more sources

A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility.

Biophysical Journal, 2008
Troponin C (TnC) belongs to the superfamily of EF-hand (helix-loop-helix) Ca(2+)-binding proteins and is an essential component of the regulatory thin filament complex.
C. Lim, Haijun Yang, Mingfeng Yang, Chien‐Kao Wang, Jianru Shi, Eric A. Berg, D. Pimentel, J. Gwathmey, R. Hajjar, M. Helmes, C. Costello, Shuanghong Huo, R. Liao   +12 more
semanticscholar   +1 more source

Computational Exploration and Characterization of Potential Calcium Sensitizing Mutations in Cardiac Troponin C. [PDF]

J Chem Inf Model, 2022
Hantz ER, Lindert S.
europepmc   +1 more source