Results 71 to 80 of about 19,854,960 (401)
PLoS ONE, 2020 BackgroundDespite the use of high-sensitive cardiac troponin there remains a group of high-sensitive cardiac troponin negative patients with unstable angina with a non-neglectable risk for future adverse cardiovascular events, emphasising the need for ...
Mirthe Dekker +10 more
doaj +1 more source
BMJ Open, 2022 Objective Cardiac troponin is used as a prognostic biomarker after cardiac surgery. However, numerous confounding elements, such as inflammation, liver and renal function biomarkers, have been associated with troponin variations.
Arthur Clement +3 more
doaj +1 more source
Ca2(+)-dependent interactions between the C-helix of troponin-C and troponin-I. Photocross-linking and fluorescence studies using a recombinant troponin-C. [PDF]
Journal of Biological Chemistry, 1990 We have used in vitro mutagenesis to synthesize in Escherichia coli a recombinant rabbit skeletal troponin-C (designated as TnC57) in which Cys-98 was replaced with leucine, and Ala-57 in the C-helix of the N-terminal domain was replaced with cysteine.
John Gergely +3 more
openaire +2 more sources
Journal of Biological Chemistry, 2010 In this study we explore the mechanisms by which a double mutation (E59D/D75Y) in cardiac troponin C (CTnC) associated with dilated cardiomyopathy reduces the Ca2+-activated maximal tension of cardiac muscle. Studying the single mutants (i.e.
David Dweck +3 more
semanticscholar +1 more source
Advanced Materials, EarlyView.This study presents an implantable reinforced cardiac patch (RCPatch) combining volumetrically 3D‐printed metamaterials with melt‐electrowritten (MEW) meshes. The design integrates tunable stiff polymer structures with soft, cell‐laden hydrogels. The RCPatch withstands suturing, intraventricular pressure, and cardiac contraction in a large animal ...
Lewis S. Jones +12 more
wiley +1 more source
Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications
Advanced Materials, EarlyView.Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi +7 more
wiley +1 more source
Molecular dynamics simulations of the cardiac troponin complex performed with FRET distances as restraints. [PDF]
PLoS ONE, 2014 Cardiac troponin (cTn) is the Ca(2+)-sensitive molecular switch that controls cardiac muscle activation and relaxation. However, the molecular detail of the switching mechanism and how the Ca(2+) signal received at cardiac troponin C (cTnC) is ...
Jayant James Jayasundar +4 more
doaj +1 more source
Cats with thermal burn injuries from California wildfires show echocardiographic evidence of myocardial thickening and intracardiac thrombi. [PDF]
, 2020 Recent increases in the prevalence and severity of wildfires in some regions have resulted in an increased frequency of veterinary burn patients. Few studies exist regarding diagnostics and management of burn wounds in veterinary patients and current ...
Epstein, Steven E +4 more
core
Utility of B-type natriuretic peptide in predicting medium-term mortality in patients undergoing major non-cardiac surgery [PDF]
, 2007 We assessed the ability of pre-operative B-type natriuretic peptide (BNP) levels to predict medium-term mortality in patients undergoing major noncardiac surgery.
Amiri, Amir R. +5 more
core +1 more source
The Bionic Interface: Considering the Material Mediated Electrical Stimulation of Stem Cells
Advanced Materials, EarlyView.Electrical stimulation directs stem cell fate in tissue engineering. Cellular responses are influenced by membrane properties, intrinsic cell state, material charge‐transport characteristics, and the applied electrical signal. Additionally, a material’s ability to inject, store, and redistribute charge further modulates these responses.
Kaiwen Zhang +6 more
wiley +1 more source