Results 1 to 10 of about 12,042,484 (342)

Role of Admission Troponin‐T and Serial Troponin‐T Testing in Predicting Outcomes in Severe Sepsis and Septic Shock

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundTroponin‐T elevation is seen commonly in sepsis and septic shock patients admitted to the intensive care unit. We sought to evaluate the role of admission and serial troponin‐T testing in the prognostication of these patients.
Saraschandra Vallabhajosyula, Ankit Sakhuja, Jeffrey B. Geske, Mukesh Kumar, Joseph T. Poterucha, Rahul Kashyap, Kianoush Kashani, Allan S. Jaffe, Jacob C. Jentzer   +8 more
doaj   +2 more sources

Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T [PDF]

International Journal of Biological Sciences, 2006
Protein dephosphorylation by protein phosphatase 1 (PP1), acting in concert with protein kinase C (PKC) and protein kinase A (PKA), is a pivotal regulatory mechanism of protein phosphorylation.
Brian H Crawford, Robert L. Raynor, Nathan M. Jideama, A K M A Hussain   +3 more
doaj   +4 more sources

Anti–Cardiac Troponin Autoantibodies Are Specific to the Conformational Epitopes Formed by Cardiac Troponin I and Troponin T in the Ternary Troponin Complex [PDF]

Clinical Chemistry, 2017
Abstract BACKGROUND Autoantibodies to cardiac troponins (TnAAbs) could negatively affect cardiac troponin I (cTnI) measurements by TnAAbs-sensitive immunoassays. We investigated the epitope specificity of TnAAbs and its influence on cTnI immunodetection in patients with acute myocardial infarction ...
Alexandra V Vylegzhanina, Kogan Ae, Olga V Antipova, Ekaterina V. Koshkina, Anastasia V. Bereznikova, A.N. Kara, Ivan A Katrukha, Alexey G. Katrukha   +7 more
openaire   +4 more sources

Cardiac troponin T as a serum biomarker of respiratory impairment in amyotrophic lateral sclerosis [PDF]

Annals of Clinical and Translational Neurology
Objective Informative biomarkers are an urgent need in the management of amyotrophic lateral sclerosis. Serum cardiac troponin T is elevated in the majority of amyotrophic lateral sclerosis patients and increases with disease progression.
Teresa Koch, Rachel Fabian, Leonie Weinhold, Franz‐W. Koch, Saman Barakat, Sergio Castro‐Gomez, Torsten Grehl, Sarah Bernsen, Patrick Weydt   +8 more
doaj   +2 more sources

Troponin Cut-Offs for Acute Myocardial Infarction in Patients with Impaired Renal Function—A Systematic Review and Meta-Analysis

Diagnostics, 2022
Identifying acute myocardial infarction in patients with renal disease is notoriously difficult, due to atypical presentation and chronically elevated troponin.
Jan Kampmann, James Heaf, Christian Backer Mogensen, Andreas Kristian Pedersen, Jeff Granhøj, Hans Mickley, Frans Brandt   +6 more
doaj   +1 more source

Renal Elimination of Troponin T and Troponin I [PDF]

Clinical Chemistry, 2003
Cardiovascular complications represent the predominant cause of death in patients in the terminal stage of renal failure. Increased concentrations of cardiac troponin T (cTnT) may be a valuable predictor of cardiac risk (1)(2). However, cardiac troponin I (cTnI), clinical symptoms, and electrocardiogram (ECG) indications may be absent in patients with ...
Andreas Lun, Pranav Sinha, Rolfdieter Krause, Claudia Altermann, Gernot Asmus, Rainer Möbes, Friedrich Priem, Berthold Hocher, Reinhard Ziebig, Hartmut Kern, Babette Lorenz   +10 more
openaire   +3 more sources

Impact of genotype and phenotype on cardiac biomarkers in patients with transthyretin amyloidosis - Report from the Transthyretin Amyloidosis Outcome Survey (THAOS). [PDF]

PLoS ONE, 2017
AIM:Cardiac troponins and natriuretic peptides are established for risk stratification in light-chain amyloidosis. Data on cardiac biomarkers in transthyretin amyloidosis (ATTR) are lacking.
Arnt V Kristen, Mathew S Maurer, Claudio Rapezzi, Rajiv Mundayat, Ole B Suhr, Thibaud Damy, THAOS investigators   +6 more
doaj   +1 more source

Troponin T and Survival following Cardiac Surgery in Patients Supported with Extracorporeal Membrane Oxygenation for Post-Cardiotomy Shock

Diagnostics, 2023
Background: While troponin is an established biomarker of cardiac injury, its prognostic significance in post-cardiotomy cardiogenic shock patients supported by venoarterial extracorporeal membrane oxygenation (PCCS–VA-ECMO) remains unclear.
Małgorzata Celińska-Spodar, Marta Załęska Kocięcka, Ilona Kowalik, Piotr Kołsut, Ewa Sitkowska-Rysiak, Jarosław Szymański, Janina Stępińska   +6 more
doaj   +1 more source

The Prognostic Significance of Troponin I and Troponin T [PDF]

Academic Emergency Medicine, 1998
Abstract. Objectives: To determine and compare the prognostic abilities of early, single‐sample measurements of cardiac troponin I (cTn‐I), cardiac troponin T (cTn‐T), creatine kinase‐MB (CK‐MB) among ED patients with possible myocardial ischemia. Methods: Prospective collection of clinical and serologic data using an identity‐unlinked technique from
Edward S. Bessman, Daniel W. Chan, Dai J. Li, Gabor D. Kelen, Jennifer L. Cox, Gary B. Green   +5 more
openaire   +3 more sources

Troponin

Neonatal Network, 2013
Troponin T and I can be found within the myocardial filaments. Measuring these cardiac troponin levels in full-term newborns and premature infants has not become a common practice in the neonatal intensive care unit and newborn nurseries. Research studies are discovering that an elevation in troponin T and I levels can be directly correlated with the ...
Daniele, Ottinger, Patricia, Nash
openaire   +5 more sources