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> “The River Eddy Whirls” > > – The Lady of Shalott , Lord Alfred Tennyson (1842) In this issue of Circulation: Cardiovascular Interventions , Herrmann et al1 report data from a contemporary registry from the Mayo clinic. The study examined the relationship between the magnitude of periprocedural myonecrosis with percutaneous coronary intervention ...
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Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen+5 more
core +1 more source
Background Metformin has favorable effects on cardiovascular outcomes in both newly onset and advanced type 2 diabetes, as previously reported findings from the UK Prospective Diabetes Study and the HOME trial have demonstrated.
Johanna M. G. Stultiens+7 more
doaj +1 more source
We read with interest the report of Kontos et al. ([1][1]), which showed that any detectable troponin I in the serum of patients admitted with chest pain was associated with worse outcomes. We recently reported the results of a similar study involving troponin T levels ([2][2]), and we found ...
Nisha Chandra-Strobos+1 more
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Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis. [PDF]
BACKGROUND: Elevated serum cardiac troponin T (cTnT) and I (cTnI) can occur in patients with chronic kidney disease. Differences in cTn concentrations between cTnT and cTnI have been reported but the mechanism of such discrepancy has not been ...
Adams+32 more
core +1 more source
Are troponins confusing? [PDF]
The cardiospecificity and sensitivity of cardiac troponin measurement has proved to be a two edged sword for the laboratory and the clinician The ability to measure the cardiac specific markers, cardiac troponin T (cTnT) and cardiac troponin I (cTnI) (the cardiac troponins), has produced a paradigm shift in the assessment of patients with suspected ...
P O Collinson, P J Stubbs
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Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
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Background: Unsuspected morbidity and mortality in cerebrovascular stroke (CVS) patients remain a serious issue in critical medicine field. Patients with CVS are at increased risk of developing cardiac complications which explains the high morbidity and ...
Mohammed Amin+3 more
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Troponin and anti-troponin autoantibody levels in patients with ventricular noncompaction. [PDF]
Ventricular hypertrabeculation/noncompaction is a morphologic and functional anomaly of myocardium characterized by prominent trabeculae accompanied by deep recessus.
Hatice Betül Erer+8 more
doaj +1 more source
Prognostic role of high-sensitivity cardiac troponin T in patients with cardiac sarcoidosis: insights from ILLUMINATE-CS. [PDF]
Abstract Aims The prognostic role of high‐sensitivity cardiac troponin T (hs‐cTnT) as a biomarker in patients with cardiac sarcoidosis (CS) has yet to be fully determined, especially when compared with B‐type natriuretic peptide (BNP). Methods and Results In this post‐hoc analysis of the ILLUMINATE‐CS (ILLUstration of the Management and prognosIs of ...
Baba Y+10 more
europepmc +2 more sources