Results 191 to 200 of about 163,766 (299)

Linkage of kynurenine pathway metabolites to neuroinflammation in drug-naive children with attention-deficit/hyperactivity disorder: A cross-sectional, case-control study. [PDF]

World J Clin Pediatr
Ünal K, Taş Torun Y, Erol ME, Özbaş C, Kurt ZK.   +4 more
europepmc   +1 more source

Altered Cerebrospinal Fluid Tryptophan–Kynurenine Pathway Metabolism in Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Alterations in tryptophan–kynurenine (TRP‐KYN) metabolism, which is associated with neuroinflammation, remain unclear in multiple system atrophy (MSA). Objective The aim was to investigate cerebrospinal fluid (CSF) TRP metabolites in MSA and their associations with other biomarkers.
Ryunosuke Nagao, Kazuya Kawabata, Yasuaki Mizutani, Sayuri Shima, Akihiro Ueda, Mizuki Ito, Yasuhiro Maeda, Akihiro Mouri, Hirohisa Watanabe   +8 more
wiley   +1 more source

A metabolic constraint in de novo NAD+ synthesis drives mucosal inflammation in IBD. [PDF]

J Crohns Colitis
Wehkamp L, Harris DMM, Kim NM, Alsaadi AI, Wu Q, Oumari M, Taubenheim J, Volk V, Credidio G, Koncina E, Mukherjee PK, Tran F, Mekdoud T, Yu M, Sievers LK, Pavlidis P, Powell N, Wang S, Fung I, Waetzig GH, Rousseaux C, Desreumaux P, Rieder F, Letellier E, Waschina S, Meyer TF, Adolph T, D'Haens G, Kaleta C, Feuerhake F, Verstockt B, McReynolds MR, Rosenstiel P, Schreiber S, Aden K.   +34 more
europepmc   +1 more source

Modeling n‐Butyl Acrylate Polymerization using Complementary Modeling Techniques

Macromolecular Reaction Engineering, EarlyView.
Two different simulation methods are used for the radical polymerization of nBA: deterministic in Predici and stochastic with mcPolymer. It has been successfully implemented across a wide temperature range. It turns out that the partially different implementation of chain‐length‐dependent termination and β‐scission are important for obtaining ...
Marco Drache, Inka Helmer, Sebastian Klepatz, Kristina Maria Zentel   +3 more
wiley   +1 more source

Antipathogenic carbon dots synthesized from fluorescent amino acids and their photodynamic activity. [PDF]

Discov Nano
Suner SS, Sahiner M, Torres JH, Sahiner N.   +3 more
europepmc   +1 more source

Assessing trade‐off risk between crop production and vertebrate biodiversity in three African countries

People and Nature, EarlyView.
Abstract Governments worldwide are committed to eliminating hunger and conserving biodiversity, reflected in United Nations Sustainable Development Goals 2 (Zero Hunger) and 15 (Life on Land). Expanding agricultural lands to meet growing food demands often threatens biodiversity, creating potential trade‐offs between these objectives. To understand the
Abbie S. A. Chapman, Selase Kofi Adanu, Carole Dalin, Adam Devenish, Geoffrey H. Griffiths, Elizabeth J. Z. Robinson, Barbara Adolph, Phil Franks, Tagel Gebrehiwot, Jacob Mwitwa, Nathalie Seddon, Joseph A. Tobias, Tim Newbold   +12 more
wiley   +1 more source

Extracellular ATP drives tryptophan metabolism and aryl hydrocarbon receptor activation to promote cellular senescence. [PDF]

J Biol Chem
Volonte D, Mullett SJ, Gelhaus SL, Galbiati F.   +3 more
europepmc   +1 more source

Enabling Variant Proteogenomic Assay Development Through a Peptide Target Selection Pipeline and Web Application

PROTEOMICS, EarlyView.
ABSTRACT The quantification of key protein variants can guide precision oncology to enable better identification of driver mutations. Bottom‐up assays infer parent protein levels through the quantification of surrogate peptides. Assay methods designed for absolute quantification of protein variants, such as multiple reaction monitoring mass ...
Constantinos Blidjios, Pallab Bhowmick, Vincent R. Richard, Yassene Mohammed, Christoph H. Borchers   +4 more
wiley   +1 more source

Prognostic Stratification and Subtyping of Glioblastoma Using Transient Receptor Potential Channels. [PDF]

Hum Mutat
Sun R, Zhu L, Lu Z, Wang Z, Feng S, Zhao J.   +5 more
europepmc   +1 more source

Unveiling the health‐promoting potential of Sudanese sorghum landraces: A legacy rooted in Eastern Sudan, Kassala, and the Red Sea States

PLANTS, PEOPLE, PLANET, EarlyView.
Sorghum is a staple food for hundreds of millions of people in dry regions worldwide, and improving its nutritional quality is vital for global food and health security under climate change. In this study, we evaluated traditional Sudanese sorghum varieties grown in eastern deltas to better understand their natural health‐promoting properties. We found
Khitma A. Sir Elkhatim, Manhal Gobara Hamid, Ahmed Khalifa, Mahbubjon Rahmatov, Mohammed Elsafy, Tilal Abdelhalim   +5 more
wiley   +1 more source