Results 201 to 210 of about 176,809 (302)

Color Alleviation in Hybrid Electrospun‐Electrosprayed Magnetic Paper

Macromolecular Rapid Communications, EarlyView.
A combined electrospinning/electrospraying fabrication approach enables the chromatic alleviation of the brown Color of Fe3O4 nanoparticles, by encapsulating them within polymer‐based electrosprayed microparticles that are sandwiched between electrospun fibrous layers.
Stefanos Savva, Andreas Hadjianastasi, Viktoria Theodorou, Kyriaki Louka, Vlad Mircea Socoliuc, Rodica Paula Turcu, Septimiu Cassian Tripon, Theodora Krasia‐Christoforou   +7 more
wiley   +1 more source

Endothelial indoleamine 2,3-dioxygenase 1 drives high-tryptophan diet-mediated thrombosis in cancer-bearing mice. [PDF]

Blood Vessel Thromb Hemost
Jose A, Lotfollahzadeh S, Natrakul A, Patel A, Sethuraman K, Przekop K, Del Carmen Piqueras M, Ranga A, Cabral HJ, Fillmore N, Ravid K, Chitalia VC.   +11 more
europepmc   +1 more source

Keeping It Native: Non‐Denaturing Approaches to Top‐Down Protein Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics and top‐down mass spectrometry approaches provide direct characterization of proteoforms; the specific molecular forms of proteins, including post‐translational modifications, truncations, alternative splicing, and sequence variants.
Michael Xiao, Edvaldo Vasconcelos Soares Maciel, Frederik Lermyte, Owen S. Skinner   +3 more
wiley   +1 more source

A noncanonical meiotic cohesin complex associates with specific MCM complexes to promote cohesion establishment and homolog bias. [PDF]

Sci Adv
Ma L, Jin Q, Hu D, Lin X, Fan Z, Yan R.
europepmc   +1 more source

Altered Cerebrospinal Fluid Tryptophan–Kynurenine Pathway Metabolism in Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Alterations in tryptophan–kynurenine (TRP‐KYN) metabolism, which is associated with neuroinflammation, remain unclear in multiple system atrophy (MSA). Objective The aim was to investigate cerebrospinal fluid (CSF) TRP metabolites in MSA and their associations with other biomarkers.
Ryunosuke Nagao, Kazuya Kawabata, Yasuaki Mizutani, Sayuri Shima, Akihiro Ueda, Mizuki Ito, Yasuhiro Maeda, Akihiro Mouri, Hirohisa Watanabe   +8 more
wiley   +1 more source

ATXN8OS Intermediate Expansion Acts as a Genetic Modifier in Spinocerebellar Ataxia Type 48 (SCA48/STUB1)

Movement Disorders, EarlyView.
Abstract Background Association between monoallelic STUB1 variant and expanded ATXN8OS alleles was recently reported, suggesting a pathogenic interaction that may influence spinocerebellar ataxia type 48 (SCA48) phenotype. Objectives We investigated the frequency and clinical impact of ATXN8OS in a large cohort of STUB1 carriers compared to individuals
Charlotte Mouraux, Jean‐Loup Méreaux, Claire‐Sophie Davoine, Léna Guillot Noel, Emilien Petit, Quentin Thomas, Adem Nasraoui, Anna Heinzmann, Claire Ewenczyk, Alexis Brice, Alexandra Durr, Giulia Coarelli   +11 more
wiley   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

The gut microbiota-tryptophan metabolism-immune axis in inflammatory bowel disease: Mechanisms and therapeutic prospects. [PDF]

Hum Vaccin Immunother
Wang T, Wang X, Yuan W.
europepmc   +1 more source