Results 221 to 230 of about 176,809 (302)

The Supporting Scaffold as a Structural Module for Plant Cystatin Design

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein engineering approaches have been proposed to improve the inhibitory potency of cystatins against plant pest digestive Cys proteases, typically involving point mutations in the N‐terminal trunk or inhibitory loops known to interact with the target protease.
Jonathan Tremblay   +4 more
wiley   +1 more source

Local electrostatics governs tryptophan oxidation and enables rational stability engineering in antibodies. [PDF]

open access: yesMAbs
Lenka S   +18 more
europepmc   +1 more source

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

open access: yesPest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti   +3 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

open access: yesPhytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko   +3 more
wiley   +1 more source

Liquiritigenin Ameliorates High‐Fat Diet‐Induced Hepatic Steatosis by Promoting Lipid Droplet Catabolism via PLIN2‐ATGL Regulation

open access: yesPhytotherapy Research, EarlyView.
Liquiritigenin promotes expression of CGI‐58 and enhances lipolysis by down‐regulating expression of PLIN2, thereby facilitating the catabolism of larger‐sized lipid droplets and producing smaller‐sized lipid droplets, resulting in enhanced activity of lipophagy and ameliorated hepatic steatosis. ABSTRACT Metabolic‐associated fatty liver disease (MAFLD)
Zhuoya Xu   +7 more
wiley   +1 more source

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