Results 271 to 280 of about 163,766 (299)
Some of the next articles are maybe not open access.
Advances in TRP channel drug discovery: from target validation to clinical studies
Nature Reviews Drug Discovery, 2021Ari Koivisto +2 more
exaly
2010
In the normal human body pancreatic β-cells spend most of the time in a READY mode rather than in an OFF mode. When in the READY mode, normal β-cells can be easily SWITCHED ON by a variety of apparently trivial stimuli. In the READY mode β-cells are highly excitable because of their high input resistance.
openaire +2 more sources
In the normal human body pancreatic β-cells spend most of the time in a READY mode rather than in an OFF mode. When in the READY mode, normal β-cells can be easily SWITCHED ON by a variety of apparently trivial stimuli. In the READY mode β-cells are highly excitable because of their high input resistance.
openaire +2 more sources
2007
Pain is initiated when noxious stimuli excite the peripheral terminals of specialized primary afferent neurons called nociceptors. Many molecules are involved in conversion of the noxious stimuli to the electrical signals in the nociceptor endings. Among them, TRP channels play important roles in detecting noxious stimuli.
openaire +2 more sources
Pain is initiated when noxious stimuli excite the peripheral terminals of specialized primary afferent neurons called nociceptors. Many molecules are involved in conversion of the noxious stimuli to the electrical signals in the nociceptor endings. Among them, TRP channels play important roles in detecting noxious stimuli.
openaire +2 more sources
Structural Pharmacology of TRP Channels
Journal of Molecular Biology, 2021Vera Y Moiseenkova-Bell
exaly
TRP Channels as Potential Drug Targets
Annual Review of Pharmacology and Toxicology, 2018Magdalene M Moran
exaly
Transient receptor potential (TRP) channels: a clinical perspective
British Journal of Pharmacology, 2014Arpad Szallasi
exaly
TRP-channels as key integrators of lipid pathways in nociceptive neurons
Progress in Lipid Research, 2014Marco Sisignano +2 more
exaly