Results 151 to 160 of about 1,414,547 (185)

Role of transient receptor potential channels on pathogenesis and treatment of psoriasis. [PDF]

Inflammopharmacology
da Silva AM, Nassini R, De Logu F, Ferreira J.   +3 more
europepmc   +1 more source

Itching, Ionic Channels, Immune System, Magnesium and Antioxidants. [PDF]

Clin Cosmet Investig Dermatol
Sastre MC, Soler JM, Umbert I.
europepmc   +1 more source

Gustatory function of Aedes aegypti opsins and TRPA1 in avoiding a natural insect repellent. [PDF]

Curr Biol
Chandel A, Dhavan P, Ganguly A, Singh R, Aguilar D, Lu Z, Chen Q, Montell C.   +7 more
europepmc   +1 more source

Schwann Cell TRPA1, a Proalgesic Ion Channel, Mediates Neuroinflammation and Fibromyalgia-Associated Behaviours in Mice. [PDF]

J Neurochem
Brum ES, Fialho MFP, de Araújo DSM, Landini L, Marini M, De Logu F, Nassini R, Oliveira SM.   +7 more
europepmc   +1 more source

Age-dependent alterations of TRPA1 and urocortin 1 signaling in the Edinger-Westphal nucleus in a mouse model of Alzheimer's disease. [PDF]

Sci Rep
Prókay AP, Konkoly J, Kormos V, Biró-Sütő T, Kriszta G, Szentmártoni HP, Berta G, Gaszner B, Zelena D, Pintér E.   +9 more
europepmc   +1 more source

Drosophila melanogaster mitigates gastro-oral infections by stimulating pathogen expulsion. [PDF]

BMC Microbiol
Verma S, Bhattacharyya S, Tare M, Marathe SA.   +3 more
europepmc   +1 more source

Agonist-Induced Changes in Ca2+ Permeation through the Nociceptor Cation Channel TRPA1 [PDF]

Biophysical Journal, 2010
The Ca(2+)-permeable cation channel TRPA1 acts as an ionotropic receptor for various pungent compounds and as a noxious cold sensor in sensory neurons. It is unclear what proportion of the TRPA1-mediated current is carried by Ca(2+) ions and how the permeation pathway changes during stimulation.
Thomas Voets, Karel Talavera, Bernd Nilius   +2 more
exaly   +5 more sources

Nicotine activates the chemosensory cation channel TRPA1 [PDF]

Nature Neuroscience, 2009
Topical application of nicotine, as used in nicotine replacement therapies, causes irritation of the mucosa and skin. This reaction has been attributed to activation of nicotinic acetylcholine receptors (nAChRs) in chemosensory neurons. In contrast with this view, we found that the chemosensory cation channel transient receptor potential A1 (TRPA1) is ...
Jeroen Vanoirbeek, Thomas Voets, Rudi Vennekens   +2 more
exaly   +7 more sources

Effects of N-glycosylation of the human cation channel TRPA1 on agonist-sensitivity [PDF]

Bioscience Reports, 2016
Determining the functional significance of post-translational modifications advances our understanding of many broadly-expressed proteins, and particularly ion channels. The enzymes that catalyse these modifications are often expressed in a cell-type specific manner, resulting in considerable structural diversity among post-translationally modified ...
Hanns Ulrich Zeilhofer, Marcy Zenobi-Wong, Mario A Acuna   +2 more
exaly   +6 more sources

Synthetic cation channel: reconstructing the ion permeation pathway of TRPA1 in an artificial system

RSC Advances
The carboxyl-modified ion permeation pathway in TRPA1 channel protein was reconstructed in an artificial system. The transport activity of this artificial channel is tunable via external pH due to the carboxyl groups in the ion permeation pathway.
Junbiao Chang, Pengyang Xin, Gongming Zhu   +2 more
exaly   +3 more sources