Results 161 to 170 of about 6,247 (194)

Mechanosensitive Ion Channels: Molecular Hubs Integrating Skeletal Muscle Adaptation and Systemic Homeostasis. [PDF]

open access: yesInt J Biol Sci
Zhao C   +10 more
europepmc   +1 more source

Piezo1-induced durotaxis of pancreatic stellate cells depends on TRPC1 and TRPV4 channels.

open access: yesJ Cell Sci
Budde I   +11 more
europepmc   +1 more source

TRPC1 channels regulate directionality of migrating cells [PDF]

open access: yesPflugers Archiv European Journal of Physiology, 2008
Cell migration depends on the generation of structural asymmetry and on different steps: protrusion and adhesion at the front and traction and detachment at the rear part of the cell. The activity of Ca(2+) channels coordinate these steps by arranging intracellular Ca(2+) signals along the axis of movement.
Peter Dieterich, Schwab A, Nilius B
exaly   +6 more sources

TRPC1 Is Essential for In Vivo Angiogenesis in Zebrafish [PDF]

open access: yesCirculation Research, 2010
Rationale : Wiring vascular and neural networks are known to share common molecular signaling pathways. Activation of transient receptor potential type C channels (TRPCs) has recently been shown to
Jiu-Lin Du
exaly   +6 more sources

TRPC1: The housekeeper of the hippocampus

open access: yesCell Calcium
The non-selective cation channel TRPC1 is highly expressed in the brain. Recent research shows that neuronal TRPC1 forms heteromeric complexes with TRPC4 and TRPC5, with a small portion existing as homotetramers, primarily in the ER. Given that most studies have focused on the role of heteromeric TRPC1/4/5 complexes, it is crucial to investigate the ...
Oleksandra Tiapko   +2 more
exaly   +3 more sources
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TRPC1 exacerbate metastasis in gastric cancer via ciRS-7/miR-135a-5p/TRPC1 axis

Biochemical and Biophysical Research Communications, 2020
Metastasis is frequently occurred in end-stage GC. Nevertheless, the initiation and progression of metastasis in GC remains unclear. The transient receptor potential canonical (TRPC) has been confirmed to be crucial for metastasis in many kinds of tumors, including GC. However, the molecular mechanisms regulating TRPC1 is unclear.
Mudan Ren
exaly   +3 more sources

Upregulation of TRPC1 in the development of cardiac hypertrophy

Journal of Molecular and Cellular Cardiology, 2007
The importance of Ca(2+) entry in the cardiac hypertrophic response is well documented, but the actual Ca(2+) entry channels remain unknown. Transient receptor potential (TRP) proteins are thought to form either homo- or heteromeric Ca(2+) entry channels that are involved in the proliferation and differentiation of various cells.
Takayoshi, Ohba   +9 more
openaire   +2 more sources

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