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Loss of Endothelial TRPC1 Induces Aortic Hypercontractility and Hypertension
Circulation ResearchBACKGROUND: The increasing prevalence of obesity-related cardiovascular diseases demands a better understanding of the contribution of different cell types to vascular function for developing new treatment strategies. Previous studies have established a fundamental role of TRPC1 (transient receptor potential channel canonical ...
Yifei Zhu +8 more
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TRPC1: a core component of store-operated calcium channels
Biochemical Society Transactions, 2007The TRPC (transient receptor potential canonical) proteins are activated in response to agonist-stimulated PIP2 (phosphatidylinositol 4,5-bisphosphate) hydrolysis and have been suggested as candidate components of the elusive SOC (store-operated calcium channel). TRPC1 is currently the strongest candidate component of SOC.
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Function of the Porcine TRPC1 Gene in Myogenesis and Muscle Growth
Cells, 2021Ran Zhang, Ruixue Nie, Yu Fu
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TRPC1 Associates With BK Ca Channel to Form a Signal Complex in Vascular Smooth Muscle Cells
Circulation Research, 2009, Xiaoqiang Yao, Yu Huang
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TRPC1 protein forms only one type of native store-operated channels in HEK293 cells
Biochimie, 2013Vladimir Vigont +2 more
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