Results 81 to 90 of about 6,247 (194)
Lack of TRPC1 channels impairs skeletal muscle regeneration [PDF]
, 2010 We have previously showed in vitro that Ca2+ entry through TRPC1 ion channels regulates myoblasts migration and differentiation by activating calpain, a Ca2+-dependent protease which cleaves myristoylated alanine-rich C-kinase substrate (MARCKS) protein ...
Gailly, Philippe +5 more
core
Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology
Advanced Science, Volume 13, Issue 33, 15 June 2026.Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu +4 more
wiley +1 more source
The FASEB Journal, 2009 Prolonged exposure to aveolar hypoxia causes pulmonary hypertension (PAH) and right heart hypertrophy. Hypoxic PAH is associated with alterations in Ca 2+ homeostasis in pulmonary arterial smooth muscle cells (PASMCs).
Xiao‐Ru Yang +3 more
openaire +1 more source
Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1−/- mice [PDF]
, 2019 We have previously provided pharmacological evidence that stimulation of calcium-sensing receptors (CaSR) induces endothelium-dependent relaxations of rabbit mesenteric arteries through activation of heteromeric TRPV4/TRPC1 channels and nitric oxide (NO)
Kazi S. Jahan (7489502) +5 more
core +1 more source
The effect of chronic constriction injury after a period of endurance training on the expression of TRPC1 and TRPC3 in the plantaris muscle of male Wistar rats [PDF]
فصلنامه ابن سینا, 2023 Background and aims: Due to the role of TRPC1/3 in muscle atrophy, this study aimed to investigate the effect of Chronic Constriction Injury (CCI) after a period of endurance training on TRPC1/3 gene expression in the plantaris muscle of male Wistar rats.
Abdolreza Kazemi +3 more
doaj
Smart Medicine, Volume 5, Issue 3, June 2026.Magnetic fields modulate macrophage‐cancer crosstalk through the STING‐TRPC1 axis. Exposure reprograms macrophages toward the anti‐cancer phenotype. Exposing cancer cells modulates cancer secretome to promote polarization and selective recruitment of M1‐tumoricidal macrophages, enhancing cancer immunogenicity.
Viresh Krishnan Sukumar +7 more
wiley +1 more source
Die Rolle von TRPC1 in CA1-Neuronen des murinen Hippocampus [PDF]
, 2011 Die klassischen (classical) "transient receptor potential"-Kanäle (TRPC1-TRPC7) bilden eine Familie von nichtselektiven Kationenkanälen, die Phospholipase C-abhängig aktiviert werden und in verschiedensten Geweben exprimiert werden.(z.B.
Kepura, Frauke, Homberg, Uwe (Prof. Dr.)
core +1 more source
Advanced Materials, Volume 38, Issue 26, 8 May 2026.A bioinspired nanozyme—triphenylphosphonium (TPP)‐dendritic mesoporous silica nanoparticle (DMSN)‐Fe/Cu—mimics mitochondrial complex IV and targets mitochondria to regulate cellular energy metabolism. This approach markedly boosts bone regeneration in vivo, as demonstrated by enhanced bone volume and mineral density in critical‐sized bone defects rat ...
Yuwen Wang +16 more
wiley +1 more source
Specific association of the gene product of PKD2 with the TRPC1 channel [PDF]
Proceedings of the National Academy of Sciences, 1999 The function(s) of the genes ( PKD1 and PKD 2) responsible for the majority of cases of autosomal dominant polycystic kidney disease is unknown. While PKD1 encodes a large integral membrane protein containing several structural motifs found in known proteins involved ...
Tsiokas, Leonidas +5 more
openaire +3 more sources
British Journal of Pharmacology, Volume 183, Issue 9, Page 2139-2165, May 2026.Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi +14 more
wiley +1 more source