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Osmomechanical-Sensitive TRPV Channels in Mammals
2017Within the transient receptor potential (TRP) superfamily of ion channels (Cosens and Manning, 1969; Montell and Rubin, 1989; Wong et al., 1989; Hardie and Minke, 1992; Zhu et al., 1995), the TRPV subfamily stepped into the limelight in 1997 (Colbert et al., 1997; Caterina et al., 1997), when its founding members, OSM-9 in Caenorhabditis elegans and ...
Carlene Moore, Wolfgang B. Liedtke
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Fevers, TRPV channels, and birth defects
Science, 2017Reproductive Biology Cardiac and craniofacial birth defects are common, but many cannot be attributed to specific mutations. An environmental trigger associated with these birth defects is maternal fever during the first trimester. Using chick and zebrafish embryos, Hutson et al.
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Link Between TRPV Channels and Mast Cell Function
2007Mast cells are tissue-resident immune effector cells. They respond to diverse stimuli by releasing potent biological mediators into the surrounding tissue, and initiating inflammatory responses that promote wound healing and infection clearance. In addition to stimulation via immunological routes, mast cells also respond to polybasic secretagogues and ...
H, Turner, K A, del Carmen, A, Stokes
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Pymetrozine activates TRPV channels of brown planthopper Nilaparvata lugens
Pesticide Biochemistry and Physiology, 2019The commercial insecticide pymetrozine has been extensively used for brown planthopper control in East Asia. The transient receptor potential vanilloid (TRPV) channel, which consists of two proteins, Nanchung (Nan) and Inactive (Iav), has recently been shown to be the molecular target of pymetrozine in the fruit fly (Drosophila melanogaster) and pea ...
Li-Xiang Wang +8 more
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TRPV Channels’ Role in Osmotransduction and Mechanotransduction
2007In signal transduction of metazoan cells, transient receptor potential (TRP) ion channels have been identified that respond to diverse external and internal stimuli, among them osmotic and mechanical stimuli. This chapter will summarize findings on the TRPV subfamily, both its vertebrate and invertebrate members.
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Acta bio-medica : Atenei Parmensis, 2009
Vanilloids are natural molecules identified in a plethora of foods normally ingested through the diet. They mediate apoptosis through a direct pathway (independent of TRPV-1, the receptor for vanilloids) and through an indirect pathway, i.e., thanks to the interaction with TRPV-1 and the successive intracellular calcium growth [Ca2+]i. Some vanilloids,
Ziglioli, Francesco +5 more
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Vanilloids are natural molecules identified in a plethora of foods normally ingested through the diet. They mediate apoptosis through a direct pathway (independent of TRPV-1, the receptor for vanilloids) and through an indirect pathway, i.e., thanks to the interaction with TRPV-1 and the successive intracellular calcium growth [Ca2+]i. Some vanilloids,
Ziglioli, Francesco +5 more
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TRPV channels as insecticide targets
2016 International Congress of Entomology, 2016openaire +1 more source